Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   QJV49_RS02915 Genome accession   NZ_CP124538
Coordinates   607684..609159 (-) Length   491 a.a.
NCBI ID   WP_225512071.1    Uniprot ID   A0AA49IIV7
Organism   Lactococcus sp. NH2-7C     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 602684..614159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QJV49_RS02895 (QJV49_02895) murG 602816..603889 (-) 1074 WP_225512075.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  QJV49_RS02900 (QJV49_02900) murD 604105..605457 (-) 1353 WP_225512074.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  QJV49_RS02905 (QJV49_02905) - 605788..606129 (-) 342 WP_225512073.1 P-II family nitrogen regulator -
  QJV49_RS02910 (QJV49_02910) - 606261..607502 (-) 1242 WP_225512072.1 ammonium transporter -
  QJV49_RS02915 (QJV49_02915) covS 607684..609159 (-) 1476 WP_225512071.1 HAMP domain-containing histidine kinase Regulator
  QJV49_RS02920 (QJV49_02920) covR 609168..609860 (-) 693 WP_225512070.1 response regulator transcription factor Regulator
  QJV49_RS02925 (QJV49_02925) - 610016..610546 (-) 531 WP_225512069.1 DUF177 domain-containing protein -
  QJV49_RS02930 (QJV49_02930) - 610677..610922 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  QJV49_RS02935 (QJV49_02935) - 611078..611542 (-) 465 WP_225512068.1 hypothetical protein -
  QJV49_RS02940 (QJV49_02940) - 611624..611986 (-) 363 WP_225512067.1 TIGR02328 family protein -
  QJV49_RS02945 (QJV49_02945) - 612451..613287 (-) 837 WP_255597715.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56181.11 Da        Isoelectric Point: 4.8681

>NTDB_id=826311 QJV49_RS02915 WP_225512071.1 607684..609159(-) (covS) [Lactococcus sp. NH2-7C]
MKKLFTFNKKKETVGESSTKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=826311 QJV49_RS02915 WP_225512071.1 607684..609159(-) (covS) [Lactococcus sp. NH2-7C]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAGGGGAAAGTTCAACTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATCAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAACGGTGAGTCTGAAGGAATGAGTTTGGGGAG
TATTATTGGCACACGGAAAGCTTTTTATATTTATGATTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GCTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCGGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAATCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATAGTCGCTCAGATGATTGGTTATTTCATGGCTAATTATTTTA
TGAAACCATTGGAAAAACTTTATCAGGGTATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCACGTTTACAACGATATGATGTTGAAGATGAAGGCATATCTCGAACAGCA
AAATCGATTTGTTTCTGATGTTTCTCATGAATTAAGAACACCCTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGTCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCACTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGTCTTATTTATCCAA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGCTTACGAATTCTGTTAGATAATGCTGCTAAATATTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCCGAGGATGAACAGTTTGTGATTACGAGTGTGTCTGACAAAGGAATTGGAAT
TTCAGAAGAGGATATTAATCATCTTTTTGAACGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTACCAATTTTAGCTCGATTGGCCGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACTCTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

ArlS sensor domain (ArlS_N)

(54-185)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

99.185

100

0.992