Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QFX58_RS03640 Genome accession   NZ_CP123745
Coordinates   724594..725310 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 1.7     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 719594..730310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX58_RS03620 - 720688..721638 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  QFX58_RS03625 - 721787..723271 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  QFX58_RS03630 - 723268..724227 (+) 960 WP_001253312.1 carbohydrate kinase -
  QFX58_RS03635 - 724415..724522 (-) 108 WP_001790167.1 hypothetical protein -
  QFX58_RS03640 agrA 724594..725310 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  QFX58_RS03645 agrC 725329..726621 (-) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  QFX58_RS03650 agrD 726646..726786 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  QFX58_RS03655 agrB 726783..727352 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  QFX58_RS03660 hld 727642..727722 (+) 81 WP_000046022.1 delta-hemolysin -
  QFX58_RS03665 - 728319..729104 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  QFX58_RS03670 - 729465..730091 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=822244 QFX58_RS03640 WP_000688492.1 724594..725310(-) (agrA) [Staphylococcus aureus strain 1.7]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=822244 QFX58_RS03640 WP_000688492.1 724594..725310(-) (agrA) [Staphylococcus aureus strain 1.7]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1