Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   R2B38_RS12640 Genome accession   NZ_CP137549
Coordinates   2891994..2892674 (-) Length   226 a.a.
NCBI ID   WP_318016317.1    Uniprot ID   -
Organism   Streptomyces sp. N50     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 2886994..2897674
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2B38_RS12630 (R2B38_12630) - 2889463..2890470 (+) 1008 WP_318016316.1 hypothetical protein -
  R2B38_RS12635 (R2B38_12635) clpX 2890548..2891834 (-) 1287 WP_033285988.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  R2B38_RS12640 (R2B38_12640) clpP 2891994..2892674 (-) 681 WP_318016317.1 ATP-dependent Clp protease proteolytic subunit Regulator
  R2B38_RS12645 (R2B38_12645) clpP 2892725..2893327 (-) 603 WP_033285987.1 ATP-dependent Clp protease proteolytic subunit Regulator
  R2B38_RS12650 (R2B38_12650) tig 2893666..2895033 (-) 1368 WP_318016318.1 trigger factor -
  R2B38_RS12665 (R2B38_12665) - 2895728..2895922 (-) 195 WP_318016319.1 hypothetical protein -
  R2B38_RS12670 (R2B38_12670) - 2896223..2897329 (+) 1107 WP_318016320.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24915.30 Da        Isoelectric Point: 4.5528

>NTDB_id=822244 R2B38_RS12640 WP_318016317.1 2891994..2892674(-) (clpP) [Streptomyces sp. N50]
MNNFPGNGLNDLARGEYTAPAAESRYVIPRFVERTSQGVREYDPYAKLFEERVIFLGVQIDDASANDVMAQLLCLESMDP
DRDISIYINSPGGSFTALTAIYDTMQFVKPDVQTVCMGQAASAAAVLLAAGTPGKRMALPNARVLIHQPYSETGRGQVSD
LEIAANEILRMRAQLEDMLAKHSTTPLDKIREDIERDKILTAEDALAYGLIDQIISTRKMNNADVR

Nucleotide


Download         Length: 681 bp        

>NTDB_id=822244 R2B38_RS12640 WP_318016317.1 2891994..2892674(-) (clpP) [Streptomyces sp. N50]
GTGAACAACTTCCCCGGCAACGGCCTGAACGACCTCGCACGCGGCGAATACACGGCTCCCGCCGCCGAGTCCCGTTACGT
GATCCCGCGCTTCGTGGAGCGCACCTCGCAGGGCGTCCGTGAGTACGACCCGTACGCGAAGCTCTTCGAGGAGCGCGTGA
TCTTCCTCGGTGTCCAGATCGACGACGCGTCGGCCAACGACGTCATGGCGCAGCTGCTGTGCCTGGAGTCGATGGACCCG
GACCGCGACATCTCCATCTACATCAACAGCCCGGGCGGCTCCTTCACGGCCCTGACTGCGATCTACGACACGATGCAGTT
CGTGAAGCCGGACGTCCAGACGGTCTGCATGGGCCAGGCCGCGTCCGCCGCCGCCGTCCTGCTGGCGGCCGGTACGCCGG
GCAAGCGCATGGCGCTGCCGAACGCGCGCGTGCTGATCCACCAGCCGTACAGCGAGACGGGCCGGGGCCAGGTCTCCGAC
CTCGAGATCGCGGCCAACGAGATCCTCCGCATGCGTGCCCAGCTGGAGGACATGCTGGCCAAGCACTCGACGACCCCGCT
GGACAAGATCCGCGAGGACATCGAGCGCGACAAGATCCTCACGGCCGAGGATGCCCTGGCGTACGGCCTGATCGACCAGA
TCATCTCCACCCGGAAGATGAACAACGCCGACGTCCGCTGA

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(37-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

52.632

84.071

0.442
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

50.532

83.186

0.42
  clpP Streptococcus mutans UA159

44.724

88.053

0.394
  clpP Streptococcus pyogenes JRS4

45.641

86.283

0.394
  clpP Streptococcus pyogenes MGAS315

45.641

86.283

0.394
  clpP Streptococcus pneumoniae Rx1

44.898

86.726

0.389
  clpP Streptococcus pneumoniae D39

44.898

86.726

0.389
  clpP Streptococcus pneumoniae R6

44.898

86.726

0.389
  clpP Streptococcus pneumoniae TIGR4

44.898

86.726

0.389
  clpP Streptococcus thermophilus LMG 18311

45.128

86.283

0.389
  clpP Streptococcus thermophilus LMD-9

45.128

86.283

0.389
  clpP Lactococcus lactis subsp. cremoris KW2

44.388

86.726

0.385
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

43.367

86.726

0.376