Detailed information NTG0818441

Bioinformatically predicted

Overview

• Name: comGA/cglA/cilD
• Type: Machinery gene
• Locus tag: R4703_RS04890
• Genome accession: NZ_CP137100
• Coordinates: 876113..877054 (-)
• Length: 313 a.a.
• NCBI ID: WP_000249559.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain LYP
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 871113..882054

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4703_RS04860	-	871361..871636 (-)	276	WP_050202804.1	hypothetical protein	-
R4703_RS04865	-	871797..872549 (+)	753	WP_219566337.1	XRE family transcriptional regulator	-
R4703_RS04870	-	872551..873315 (+)	765	WP_219576745.1	hypothetical protein	-
R4703_RS04875	-	873622..875067 (+)	1446	WP_317818056.1	recombinase family protein	-
R4703_RS04885	comGB/cglB	875149..876165 (-)	1017	WP_073177425.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4703_RS04890	comGA/cglA/cilD	876113..877054 (-)	942	WP_000249559.1	competence type IV pilus ATPase ComGA	Machinery gene
R4703_RS04895	-	877130..877495 (-)	366	WP_000286415.1	DUF1033 family protein	-
R4703_RS04900	-	877762..879017 (+)	1256	WP_370657740.1	ISL3 family transposase	-
R4703_RS04905	-	879066..880124 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
R4703_RS04910	nagA	880287..881438 (-)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 35489.42 Da
• Isoelectric Point: 6.1829

>NTDB_id=818441 R4703_RS04890 WP_000249559.1 876113..877054(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain LYP]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHGLSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide

• Length: 942 bp

>NTDB_id=818441 R4703_RS04890 WP_000249559.1 876113..877054(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain LYP]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGCTCGGCTCGGAAAAAAGGGGCGCAAGACATTTATTTTGTCCCCAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGAAGTGGTAAGACGACCTTGATGCATGGATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGATATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (9-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	98.403	100	0.984
comGA/cglA/cilD	Streptococcus pneumoniae D39	98.403	100	0.984
comGA/cglA/cilD	Streptococcus pneumoniae R6	98.403	100	0.984
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	98.403	100	0.984
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	96.805	100	0.968
comGA	Streptococcus gordonii str. Challis substr. CH1	78.065	99.042	0.773
comGA	Streptococcus mutans UA159	66.238	99.361	0.658
comGA	Streptococcus mutans UA140	66.238	99.361	0.658
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	62.581	99.042	0.62
comGA	Lactococcus lactis subsp. cremoris KW2	55.128	99.681	0.55
comGA	Latilactobacillus sakei subsp. sakei 23K	41.912	86.901	0.364