Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   QBL76_RS08775 Genome accession   NZ_CP122304
Coordinates   1873158..1874405 (+) Length   415 a.a.
NCBI ID   WP_096709822.1    Uniprot ID   A0A366UD95
Organism   Enterococcus hirae strain DSM 20160     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1868158..1879405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QBL76_RS08755 (QBL76_08755) - 1868424..1869692 (+) 1269 WP_123875116.1 pitrilysin family protein -
  QBL76_RS08760 (QBL76_08760) - 1869685..1870974 (+) 1290 WP_088745198.1 pitrilysin family protein -
  QBL76_RS08765 (QBL76_08765) - 1871205..1872095 (+) 891 WP_010720624.1 RodZ domain-containing protein -
  QBL76_RS08770 (QBL76_08770) pgsA 1872264..1872842 (+) 579 WP_010720623.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QBL76_RS08775 (QBL76_08775) cinA 1873158..1874405 (+) 1248 WP_096709822.1 competence/damage-inducible protein A Machinery gene
  QBL76_RS08780 (QBL76_08780) recA 1874511..1875551 (+) 1041 WP_010720621.1 recombinase RecA Machinery gene
  QBL76_RS08785 (QBL76_08785) rny 1876121..1877677 (+) 1557 WP_010720620.1 ribonuclease Y -
  QBL76_RS08790 (QBL76_08790) proC 1877838..1878644 (-) 807 WP_088745196.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 45756.12 Da        Isoelectric Point: 4.7334

>NTDB_id=815041 QBL76_RS08775 WP_096709822.1 1873158..1874405(+) (cinA) [Enterococcus hirae strain DSM 20160]
MKSEIIAVGTELLLGQVVNTNATFLSEQLADLGIDVYYQTVVGDNPDRLESLLQLAETRSDLIILCGGLGPTEDDLTKEV
TAKHLGEELIQNTEGYKKLLAFFETTKRKMTENNLQQSQIIDGGIALPNRTGLALGTFYQTADHVYLLLPGPPSELKPMF
IEQARPLLEQNFPSEEMLISKVLRFYGIGESQLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTKDKHAGNQALLALE
EKVLARVGEYFYGYGDDNSLPKVVVELLKERNQTITAAESLTAGAFQSALGEISGVSQVFPGGFITYSLETKSEFLHIDD
ALLKQHGTVSQECAEQMAIQARNLAKTDYAISFTGVAGPDTLEGQPAGTVWIAVATSEGEVISQKYQFTRDRSHIRNSAV
MQGFDLIRRQLLRKK

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=815041 QBL76_RS08775 WP_096709822.1 1873158..1874405(+) (cinA) [Enterococcus hirae strain DSM 20160]
ATGAAATCAGAAATCATAGCAGTAGGGACAGAACTTTTACTAGGACAAGTAGTCAACACGAATGCCACGTTTTTATCCGA
ACAGTTAGCAGACCTCGGGATTGATGTGTATTATCAAACGGTGGTTGGTGATAATCCCGACCGCTTAGAATCATTACTCC
AATTAGCAGAAACCAGAAGTGACTTGATCATTTTATGTGGAGGGTTGGGACCGACAGAAGACGACCTGACGAAAGAAGTT
ACTGCGAAACATCTAGGGGAAGAATTGATCCAAAACACCGAAGGCTATAAAAAATTGTTAGCATTTTTTGAAACGACCAA
GCGTAAAATGACTGAAAATAATTTACAACAATCACAAATCATCGATGGGGGGATTGCTTTACCTAATCGCACAGGCTTAG
CATTAGGTACGTTCTATCAAACAGCAGACCATGTCTATCTCTTGTTACCTGGACCACCGAGCGAATTAAAGCCAATGTTC
ATTGAACAAGCTCGCCCATTATTGGAGCAAAACTTTCCATCTGAAGAAATGCTGATCTCAAAAGTTTTACGTTTTTACGG
TATCGGGGAATCCCAACTAGTCACAGAATTAAAAGACTTGATTGAAACACAGATCAACCCAACGATTGCCCCTTACGCAA
AACCTAACGAAGTCACTTTACGATTAACTGTGAAGACCAAAGACAAACATGCAGGAAACCAAGCCTTACTTGCTTTGGAA
GAAAAAGTATTGGCGAGAGTAGGTGAGTACTTCTATGGATATGGTGATGATAATTCATTGCCTAAAGTGGTCGTAGAATT
ATTAAAGGAAAGAAACCAAACAATTACTGCTGCAGAAAGTTTGACTGCTGGAGCCTTTCAATCAGCTTTGGGAGAGATCT
CTGGTGTTTCTCAAGTCTTCCCAGGAGGCTTCATTACCTATTCTTTAGAAACTAAATCAGAATTTTTACACATCGATGAT
GCACTATTGAAGCAGCATGGAACCGTCAGCCAAGAATGTGCAGAACAAATGGCTATCCAAGCACGTAATTTAGCAAAAAC
AGATTATGCGATTTCGTTTACTGGAGTGGCTGGACCAGATACCTTAGAAGGACAGCCAGCTGGAACAGTTTGGATCGCGG
TTGCAACAAGTGAAGGGGAGGTCATTTCGCAGAAATACCAATTTACCAGAGACCGTTCTCATATAAGGAATAGCGCAGTA
ATGCAAGGATTTGATCTCATTAGAAGACAACTATTAAGAAAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-411)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A366UD95

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

53.589

100

0.54
  cinA Streptococcus pneumoniae TIGR4

52.619

100

0.533
  cinA Streptococcus pneumoniae Rx1

52.381

100

0.53
  cinA Streptococcus mitis SK321

52.381

100

0.53
  cinA Streptococcus pneumoniae R6

52.381

100

0.53
  cinA Streptococcus pneumoniae D39

52.381

100

0.53
  cinA Streptococcus mitis NCTC 12261

51.905

100

0.525
  cinA Bacillus subtilis subsp. subtilis str. 168

47.458

99.518

0.472
  cinA Streptococcus suis isolate S10

43.095

100

0.436