Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   QA712_RS03800 Genome accession   NZ_CP121539
Coordinates   675925..676617 (-) Length   230 a.a.
NCBI ID   WP_003130756.1    Uniprot ID   S6EZK2
Organism   Lactococcus lactis strain MA5     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 670925..681617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA712_RS03785 (QA712_03765) - 672544..672885 (-) 342 WP_010906046.1 P-II family nitrogen regulator -
  QA712_RS03790 (QA712_03770) - 673017..674258 (-) 1242 WP_033898637.1 ammonium transporter -
  QA712_RS03795 (QA712_03775) covS 674441..675916 (-) 1476 WP_012898208.1 HAMP domain-containing histidine kinase Regulator
  QA712_RS03800 (QA712_03780) covR 675925..676617 (-) 693 WP_003130756.1 response regulator transcription factor Regulator
  QA712_RS03805 (QA712_03785) - 676773..677302 (-) 530 Protein_624 YceD family protein -
  QA712_RS03810 (QA712_03790) - 677433..677678 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  QA712_RS03815 (QA712_03795) - 677833..678297 (-) 465 WP_372757653.1 hypothetical protein -
  QA712_RS03820 (QA712_03800) - 678378..678740 (-) 363 WP_047205918.1 TIGR02328 family protein -
  QA712_RS03825 (QA712_03805) - 678976..679380 (-) 405 WP_047205917.1 hypothetical protein -
  QA712_RS03830 (QA712_03810) - 679493..680329 (-) 837 WP_332528996.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26684.36 Da        Isoelectric Point: 5.1273

>NTDB_id=812851 QA712_RS03800 WP_003130756.1 675925..676617(-) (covR) [Lactococcus lactis strain MA5]
MTSKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEATSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=812851 QA712_RS03800 WP_003130756.1 675925..676617(-) (covR) [Lactococcus lactis strain MA5]
ATGACTTCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCGCGATTCGTCTCATTAGAATTGGAGCATGAGGG
CTATGCGACTGAGATTAAAGATAATGGTCGATCTGGTCTTGAAGAAGCAACTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGACGGTTTTGAGGTAGCTCGTCGTTTACGAAAAGAAAAAGATACACCAATCATTATGATG
ACGGCACGTGATTCAACGATGGACCGTGTTGCTGGTCTTGATATTGGGGCTGATGATTATATCACTAAACCTTTTGCGAT
TGAGGAACTTTTGGCGCGTGTTCGTGCTTTCTTCCGTCGTGAAGAGCATGGTCATGCCGTTGAACGTGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGACAAAACGAATCGCACAGTTCATCGTGGTAAAAAAGTAATTGATTTAACACGTCGTGAG
TATGACCTCCTTTTGACATTGATGCAAAATGTTGGCGATGTTGTGACTCGTGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACAGAAACAAATGTTGTGGATGTTTATATTCGTTATCTTAGAAATAAAATTGATGTTGAAGGTCAAGATA
GCTATATTCAAACTGTTCGTGGCTTAGGTTATGTAATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6EZK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

100

100

1
  covR Streptococcus salivarius strain HSISS4

68.421

99.13

0.678
  vicR Streptococcus mutans UA159

45.887

100

0.461
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.435
  ciaR Streptococcus mutans UA159

37.611

98.261

0.37
  ciaR Streptococcus pneumoniae Rx1

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae D39

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae R6

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae TIGR4

36.726

98.261

0.361