Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   QA712_RS03795 Genome accession   NZ_CP121539
Coordinates   674441..675916 (-) Length   491 a.a.
NCBI ID   WP_012898208.1    Uniprot ID   -
Organism   Lactococcus lactis strain MA5     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 669441..680916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA712_RS03775 (QA712_03755) murG 669451..670524 (-) 1074 WP_003130746.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  QA712_RS03780 (QA712_03760) murD 670734..672086 (-) 1353 WP_332528999.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  QA712_RS03785 (QA712_03765) - 672544..672885 (-) 342 WP_010906046.1 P-II family nitrogen regulator -
  QA712_RS03790 (QA712_03770) - 673017..674258 (-) 1242 WP_033898637.1 ammonium transporter -
  QA712_RS03795 (QA712_03775) covS 674441..675916 (-) 1476 WP_012898208.1 HAMP domain-containing histidine kinase Regulator
  QA712_RS03800 (QA712_03780) covR 675925..676617 (-) 693 WP_003130756.1 response regulator transcription factor Regulator
  QA712_RS03805 (QA712_03785) - 676773..677302 (-) 530 Protein_624 YceD family protein -
  QA712_RS03810 (QA712_03790) - 677433..677678 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  QA712_RS03815 (QA712_03795) - 677833..678297 (-) 465 WP_372757653.1 hypothetical protein -
  QA712_RS03820 (QA712_03800) - 678378..678740 (-) 363 WP_047205918.1 TIGR02328 family protein -
  QA712_RS03825 (QA712_03805) - 678976..679380 (-) 405 WP_047205917.1 hypothetical protein -
  QA712_RS03830 (QA712_03810) - 679493..680329 (-) 837 WP_332528996.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56205.12 Da        Isoelectric Point: 4.8253

>NTDB_id=812850 QA712_RS03795 WP_012898208.1 674441..675916(-) (covS) [Lactococcus lactis strain MA5]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=812850 QA712_RS03795 WP_012898208.1 674441..675916(-) (covS) [Lactococcus lactis strain MA5]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACTGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATAAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCGACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCACGTTTACAATGATATGATGTTGAAGATGAAGGCATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCACGAGTTAAGAACACCCTTAGCTGTCTTGGATGGACATATTAACTTGCTAAATC
GGTGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTCGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGTCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGTTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTAATTACTGTTTCTGAGGATGAACAGTTTGTGATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAACGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTACCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

ArlS sensor domain (ArlS_N)

(54-185)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

99.796

100

0.998