Detailed information NTG0812686

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: RUW23_RS18930
• Genome accession: NZ_CP136014
• Coordinates: 4024423..4025640 (-)
• Length: 405 a.a.
• NCBI ID: WP_003161763.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain R18-20
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 4019423..4030640

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RUW23_RS18885 (RUW23_18885)	-	4019607..4020056 (-)	450	WP_003094670.1	MOSC domain-containing protein	-
RUW23_RS18890 (RUW23_18890)	-	4020053..4020682 (-)	630	WP_003094668.1	DUF1780 domain-containing protein	-
RUW23_RS18895 (RUW23_18895)	-	4020815..4021240 (+)	426	WP_009875877.1	GNAT family N-acetyltransferase	-
RUW23_RS18900 (RUW23_18900)	-	4021237..4021707 (+)	471	WP_003094664.1	hypothetical protein	-
RUW23_RS18905 (RUW23_18905)	-	4021704..4022393 (+)	690	WP_003103868.1	energy-coupling factor ABC transporter permease	-
RUW23_RS18910 (RUW23_18910)	-	4022499..4022708 (+)	210	WP_003094660.1	hypothetical protein	-
RUW23_RS18915 (RUW23_18915)	yacG	4022745..4022945 (-)	201	WP_003094656.1	DNA gyrase inhibitor YacG	-
RUW23_RS18920 (RUW23_18920)	coaE	4022942..4023553 (-)	612	WP_003112838.1	dephospho-CoA kinase	-
RUW23_RS18925 (RUW23_18925)	pilD	4023550..4024422 (-)	873	WP_023084740.1	type IV prepilin peptidase/methyltransferase PilD	Machinery gene
RUW23_RS18930 (RUW23_18930)	pilC	4024423..4025640 (-)	1218	WP_003161763.1	type II secretion system F family protein	Machinery gene
RUW23_RS18935 (RUW23_18935)	pilB	4025644..4027344 (-)	1701	WP_003107297.1	type IV-A pilus assembly ATPase PilB	Machinery gene
RUW23_RS18940 (RUW23_18940)	pilA/pilAI	4027575..4028039 (+)	465	WP_023129290.1	pilin	Machinery gene
RUW23_RS18945 (RUW23_18945)	-	4028197..4029510 (+)	1314	WP_223697243.1	O-antigen ligase family protein	-
RUW23_RS18955 (RUW23_18955)	nadC	4029691..4030539 (-)	849	WP_003116246.1	carboxylating nicotinate-nucleotide diphosphorylase	-

Sequence

Protein

• Length: 405 a.a.
• Molecular weight: 43998.80 Da
• Isoelectric Point: 9.8103

>NTDB_id=812686 RUW23_RS18930 WP_003161763.1 4024423..4025640(-) (pilC) [Pseudomonas aeruginosa strain R18-20]
MADKALKTSVFVWEGTDKKGTKVKGELSSQNPTLVKAQLRKQGITPVKVRKKGISLLGAGKKIKPMDIALFTRQMSTMMA
AGVPLLQSFDIISEGFDNPNMRKLVEEIKQEVAGGNSLANSLRKKPQYFDSLYCNLVDAGEQSGALETLLDRVATYKEKT
EALKAKIKKAMTYPIAVIVVAIIVSAILLIKVVPQFQSVFEGFGAELPAFTQMVINISNVLQEWWLLVLLMMGGAGFLLN
HAYKRSEKFRDATDRTVLKLPIVGAILYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFRDAVGKIKQDVSTGM
QLNFSMRTTNIFPSMAIQMTAIGEESGALDDMLAKVAGFYEQEVDNAVDNLTALMEPMIMAVLGVLVGGLIIAMYLPIFQ
LGNVV

Nucleotide

• Length: 1218 bp

>NTDB_id=812686 RUW23_RS18930 WP_003161763.1 4024423..4025640(-) (pilC) [Pseudomonas aeruginosa strain R18-20]
ATGGCGGACAAAGCGTTAAAGACCAGTGTCTTCGTATGGGAAGGCACTGACAAGAAAGGCACCAAGGTCAAGGGCGAGCT
GTCCAGCCAGAACCCGACCCTGGTCAAGGCGCAACTGCGCAAGCAGGGCATCACGCCGGTCAAGGTCCGCAAGAAAGGCA
TCTCCCTGCTGGGGGCGGGGAAGAAGATCAAGCCTATGGACATCGCCCTGTTCACCCGCCAGATGTCCACCATGATGGCC
GCCGGCGTGCCGCTGCTGCAGTCGTTCGACATCATCAGCGAAGGCTTCGACAATCCGAACATGCGCAAGCTGGTGGAGGA
GATCAAGCAGGAAGTCGCCGGCGGCAACAGCCTGGCCAACTCGCTGCGCAAGAAGCCGCAGTACTTCGACTCGCTCTACT
GCAACCTGGTGGACGCCGGCGAACAATCCGGCGCCCTGGAAACCCTGCTCGACCGGGTCGCCACCTACAAGGAAAAGACC
GAGGCGCTGAAGGCCAAGATCAAGAAGGCCATGACCTACCCGATCGCGGTGATCGTCGTCGCCATCATCGTTTCGGCGAT
CCTACTGATCAAGGTGGTGCCGCAGTTCCAGTCGGTGTTCGAGGGCTTCGGCGCCGAACTGCCGGCCTTCACCCAAATGG
TCATCAATATCTCCAACGTGCTCCAGGAATGGTGGCTCCTGGTACTGCTGATGATGGGCGGCGCCGGCTTCCTGCTGAAC
CACGCCTACAAGCGTTCGGAGAAGTTCCGCGACGCCACCGACCGCACGGTACTGAAGCTGCCTATCGTCGGCGCCATCCT
CTACAAATCCGCCGTGGCACGCTACGCGCGGACGCTGTCGACCACCTTCGCCGCCGGCGTGCCATTGGTGGAAGCCCTCG
ACTCGGTTTCCGGCGCCACCGGCAACGTGGTGTTCAGGGACGCGGTGGGCAAGATCAAGCAGGACGTGTCCACCGGCATG
CAGCTGAACTTCTCCATGCGCACCACCAACATCTTCCCCAGCATGGCCATCCAGATGACCGCCATCGGCGAGGAGTCGGG
CGCGCTGGACGACATGCTGGCCAAGGTCGCTGGCTTCTACGAGCAGGAAGTGGATAATGCCGTGGACAACCTGACCGCCC
TGATGGAACCGATGATCATGGCGGTCCTCGGGGTCCTGGTCGGTGGCCTGATCATCGCCATGTACCTGCCGATCTTCCAG
CTGGGCAACGTCGTCTAA

Domains

Predicted by InterProScan.

• Type II secretion system (T2SS), protein F (T2SSF) (276-397)

• Type II secretion system (T2SS), protein F (T2SSF) (71-194)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Pseudomonas stutzeri DSM 10701	78.765	100	0.788
pilC	Acinetobacter baylyi ADP1	61.275	100	0.617
pilC	Acinetobacter baumannii D1279779	60.644	99.753	0.605
pilC	Legionella pneumophila strain ERS1305867	54.293	97.778	0.531
pilG	Neisseria gonorrhoeae MS11	46.287	99.753	0.462
pilG	Neisseria meningitidis 44/76-A	45.771	99.259	0.454
pilC	Vibrio cholerae strain A1552	41.728	100	0.417
pilC	Vibrio campbellii strain DS40M4	40.898	99.012	0.405
pilC	Thermus thermophilus HB27	38.155	99.012	0.378