Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC/comC2   Type   Regulator
Locus tag   P8P68_RS07150 Genome accession   NZ_CP121467
Coordinates   1457718..1457843 (+) Length   41 a.a.
NCBI ID   WP_000799678.1    Uniprot ID   -
Organism   Streptococcus sp. D7B5     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1452718..1462843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS07125 (P8P68_07125) dnaA 1453181..1454542 (-) 1362 WP_000660625.1 chromosomal replication initiator protein DnaA -
  P8P68_RS07130 (P8P68_07130) spo0J 1454759..1455517 (-) 759 WP_049478005.1 ParB/RepB/Spo0J family partition protein Regulator
  P8P68_RS07135 (P8P68_07135) htrA 1455575..1456771 (-) 1197 WP_042903085.1 S1C family serine protease Regulator
  P8P68_RS07140 (P8P68_07140) rlmH 1456957..1457436 (+) 480 WP_042903084.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  P8P68_RS07150 (P8P68_07150) comC/comC2 1457718..1457843 (+) 126 WP_000799678.1 competence-stimulating peptide ComC Regulator
  P8P68_RS07155 (P8P68_07155) comD 1457864..1459183 (+) 1320 WP_049490808.1 competence system sensor histidine kinase ComD Regulator
  P8P68_RS07160 (P8P68_07160) comE 1459180..1459932 (+) 753 WP_000866079.1 competence system response regulator transcription factor ComE Regulator
  P8P68_RS07175 (P8P68_07175) - 1460168..1460710 (-) 543 WP_049477913.1 TetR-like C-terminal domain-containing protein -

Sequence

Protein


Download         Length: 41 a.a.        Molecular weight: 4960.73 Da        Isoelectric Point: 10.3052

>NTDB_id=812243 P8P68_RS07150 WP_000799678.1 1457718..1457843(+) (comC/comC2) [Streptococcus sp. D7B5]
MKNTVKLEQFKEVTEAELQEIRGGDWRISETIRNLIFPRRK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=812243 P8P68_RS07150 WP_000799678.1 1457718..1457843(+) (comC/comC2) [Streptococcus sp. D7B5]
ATGAAAAATACAGTAAAGTTGGAACAATTTAAAGAGGTAACAGAGGCAGAATTGCAGGAGATTCGGGGTGGAGATTGGAG
AATTTCAGAAACAATTCGTAATCTTATTTTTCCAAGAAGAAAGTAA

Domains

Predicted by InterProScan.

COMC family (ComC)

(1-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

56.098

100

0.561
  comC/comC2 Streptococcus pneumoniae TIGR4

56.098

100

0.561
  comC Streptococcus mitis SK321

56.098

100

0.561
  comC/comC1 Streptococcus pneumoniae R6

53.659

100

0.537
  comC/comC1 Streptococcus pneumoniae G54

53.659

100

0.537
  comC/comC1 Streptococcus pneumoniae D39

53.659

100

0.537
  comC/comC1 Streptococcus pneumoniae Rx1

53.659

100

0.537
  comC Streptococcus mitis NCTC 12261

47.5

97.561

0.463
  comC/comC2 Streptococcus gordonii strain NCTC7865

43.243

90.244

0.39
  comC/comC1 Streptococcus gordonii str. Challis substr. CH1

39.474

92.683

0.366