Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   P8P68_RS06275 Genome accession   NZ_CP121467
Coordinates   1292451..1293467 (-) Length   338 a.a.
NCBI ID   WP_000355379.1    Uniprot ID   -
Organism   Streptococcus sp. D7B5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1287451..1298467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS06235 (P8P68_06235) - 1288024..1288611 (+) 588 WP_084851076.1 Ltp family lipoprotein -
  P8P68_RS06240 (P8P68_06240) - 1288685..1289996 (+) 1312 Protein_1197 IS3 family transposase -
  P8P68_RS06245 (P8P68_06245) - 1289990..1290616 (-) 627 WP_278275776.1 class I SAM-dependent methyltransferase -
  P8P68_RS06250 (P8P68_06250) comGG/cglG 1290649..1291062 (-) 414 WP_049490203.1 competence type IV pilus minor pilin ComGG Machinery gene
  P8P68_RS06255 (P8P68_06255) comGF/cglF 1291040..1291501 (-) 462 WP_049490202.1 competence type IV pilus minor pilin ComGF Machinery gene
  P8P68_RS06260 (P8P68_06260) comGE/cglE 1291464..1291766 (-) 303 WP_000413367.1 competence type IV pilus minor pilin ComGE Machinery gene
  P8P68_RS06265 (P8P68_06265) comGD/cglD 1291729..1292163 (-) 435 WP_049519116.1 competence type IV pilus minor pilin ComGD Machinery gene
  P8P68_RS06270 (P8P68_06270) comGC/cglC 1292126..1292449 (-) 324 WP_000735798.1 competence type IV pilus major pilin ComGC Machinery gene
  P8P68_RS06275 (P8P68_06275) comGB/cglB 1292451..1293467 (-) 1017 WP_000355379.1 competence type IV pilus assembly protein ComGB Machinery gene
  P8P68_RS06280 (P8P68_06280) comGA/cglA/cilD 1293415..1294356 (-) 942 WP_000249575.1 competence type IV pilus ATPase ComGA Machinery gene
  P8P68_RS06285 (P8P68_06285) - 1294426..1294791 (-) 366 WP_000286396.1 DUF1033 family protein -
  P8P68_RS06290 (P8P68_06290) nagA 1294946..1296097 (-) 1152 WP_001134447.1 N-acetylglucosamine-6-phosphate deacetylase -
  P8P68_RS06295 (P8P68_06295) - 1296238..1298055 (-) 1818 WP_278275777.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38486.54 Da        Isoelectric Point: 9.4306

>NTDB_id=812236 P8P68_RS06275 WP_000355379.1 1292451..1293467(-) (comGB/cglB) [Streptococcus sp. D7B5]
MDISQVFRPKRKKLATAKQKKIITLFNNLFSSGFHLVDIISFLGRSALLEKDYVAQMHQGLAQGKSFSEMMDSLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLSKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRSSKMRVFSMLARIPFLGIFVQTYLTAYYAREWGNMISQGMELMQIFQIMQEQGSQLFNEI
GQDLAQALQNGREFSQTIATYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=812236 P8P68_RS06275 WP_000355379.1 1292451..1293467(-) (comGB/cglB) [Streptococcus sp. D7B5]
ATGGACATATCACAAGTCTTCAGGCCGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACCCTGTTTAA
CAATCTCTTCTCCAGTGGCTTTCATTTGGTGGATATTATTTCTTTCTTGGGAAGAAGTGCCCTGCTAGAAAAGGACTATG
TGGCCCAGATGCACCAAGGCTTGGCTCAGGGGAAATCTTTCTCAGAGATGATGGACAGCTTGGGCTTTTCAAGTGCTATT
GTGACCCAATTATCCCTAGCTGAAGTGCATGGAAATCTTCACCTGAGTCTGGGGAAGATAGAAGAATATCTGGATAATTT
GTCCAAGGTCAAGAAAAAGTTAATCGAAGTGGCGACCTATCCTCTGATTTTGCTGGGATTTCTCCTGCTAATCATGCTGG
GGTTGAGAAACTATCTACTTCCTCAACTGGACAGTAGCAATATCGCCACTCAAATCATCGGCAATCTGCCACAAATATTT
CTGGGACTAGTGTTGGTTTGCTCTCTATCTTTGCTTTTAGCTCTCACTTTTTACAAAAGAAGTTCCAAGATGCGGGTCTT
CTCGATGTTAGCGCGGATTCCCTTTCTAGGAATCTTTGTCCAGACTTATCTGACAGCTTATTATGCGCGTGAATGGGGCA
ATATGATTTCGCAGGGGATGGAGCTGATGCAGATTTTTCAGATCATGCAGGAACAAGGCTCACAGCTCTTTAACGAAATC
GGTCAAGATTTGGCTCAAGCCCTGCAAAATGGCCGCGAATTTTCTCAAACCATAGCGACCTATCCTTTCTTTAAAAAGGA
GTTGAGTCTCATCATCGAGTATGGGGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATCTGGTGCAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATCGTT
TTACTTTATGCGGCAATGCTTATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

92.308

100

0.923
  comGB/cglB Streptococcus mitis NCTC 12261

91.42

100

0.914
  comGB/cglB Streptococcus pneumoniae Rx1

89.645

100

0.896
  comGB/cglB Streptococcus pneumoniae D39

89.645

100

0.896
  comGB/cglB Streptococcus pneumoniae R6

89.645

100

0.896
  comGB/cglB Streptococcus pneumoniae TIGR4

89.645

100

0.896
  comYB Streptococcus gordonii str. Challis substr. CH1

73.512

99.408

0.731
  comYB Streptococcus mutans UA140

58.934

94.379

0.556
  comYB Streptococcus mutans UA159

58.934

94.379

0.556
  comGB Lactococcus lactis subsp. cremoris KW2

51.775

100

0.518