Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   P8P68_RS01365 Genome accession   NZ_CP121467
Coordinates   285543..286193 (+) Length   216 a.a.
NCBI ID   WP_000452009.1    Uniprot ID   A0AAX3TJY5
Organism   Streptococcus sp. D7B5     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 280543..291193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS01350 (P8P68_01350) - 281376..283430 (+) 2055 WP_278276025.1 G5 domain-containing protein -
  P8P68_RS01355 (P8P68_01355) ald 283619..284731 (-) 1113 WP_049501030.1 alanine dehydrogenase -
  P8P68_RS01360 (P8P68_01360) - 284907..285476 (+) 570 WP_000443757.1 GNAT family N-acetyltransferase -
  P8P68_RS01365 (P8P68_01365) comEA/celA/cilE 285543..286193 (+) 651 WP_000452009.1 helix-hairpin-helix domain-containing protein Machinery gene
  P8P68_RS01370 (P8P68_01370) comEC/celB 286177..288417 (+) 2241 WP_000084755.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  P8P68_RS01375 (P8P68_01375) infC 288637..289167 (+) 531 WP_000848185.1 translation initiation factor IF-3 -
  P8P68_RS01380 (P8P68_01380) rpmI 289200..289400 (+) 201 WP_001125942.1 50S ribosomal protein L35 -
  P8P68_RS01385 (P8P68_01385) rplT 289452..289811 (+) 360 WP_000124830.1 50S ribosomal protein L20 -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23135.27 Da        Isoelectric Point: 5.5171

>NTDB_id=812198 P8P68_RS01365 WP_000452009.1 285543..286193(+) (comEA/celA/cilE) [Streptococcus sp. D7B5]
MEVIIEKIKEYKIIVICAGLGLALGGFFLLKPTSQTSVKETNLQAEVAAVSKDSSSEKEVNKEEKEESPEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEVASQQTASGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=812198 P8P68_RS01365 WP_000452009.1 285543..286193(+) (comEA/celA/cilE) [Streptococcus sp. D7B5]
ATGGAAGTCATTATCGAAAAAATCAAAGAGTATAAAATCATTGTCATCTGTGCTGGTTTGGGTTTAGCCTTAGGCGGATT
TTTCCTGTTAAAACCAACTTCACAAACATCTGTGAAAGAAACAAATTTGCAGGCTGAAGTCGCAGCTGTTTCAAAGGATT
CATCGTCTGAAAAAGAAGTGAACAAGGAAGAGAAGGAAGAATCTCCTGAACAAGATCTGATAACAGTAGATGTCAAAGGT
GCTGTTAAATCGCCAGGGATTTATGACTTGCCAGTAGGTAGTCGTGTCAATGATGCTGTTCAAAAGGCGGGTGGCTTGAC
AGAGCAAGCAGACAGCAAATCGCTCAATCTAGCTCAGAAAGTTAGTGATGAAGCTCTGGTTTACGTTCCAACTAAGGGAG
AAGAAGTAGCTAGTCAACAGACTGCTTCTGGGACGGCCTCTTCGACGAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAAGGACTTGGTGGCAAACGAGCCCAGGATATTATCGACCATCGTGAGGCAAATGG
CAAATTCAAGTCGGTAGATGAATTAAAGAAAGTCTCTGGCATTGGCGCAAAGACCATAGAAAAGCTAAAAGATTATGTCA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(151-214)

SLBB domain (SLBB)

(76-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

93.056

100

0.931
  comEA/celA/cilE Streptococcus mitis NCTC 12261

92.593

100

0.926
  comEA/celA/cilE Streptococcus pneumoniae Rx1

92.13

100

0.921
  comEA/celA/cilE Streptococcus pneumoniae D39

92.13

100

0.921
  comEA/celA/cilE Streptococcus pneumoniae R6

92.13

100

0.921
  comEA/celA/cilE Streptococcus mitis SK321

89.352

100

0.894
  comEA Lactococcus lactis subsp. cremoris KW2

44.053

100

0.463
  comEA Latilactobacillus sakei subsp. sakei 23K

34.335

100

0.37
  comEA Staphylococcus aureus MW2

35.616

100

0.361