Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   P8P68_RS01370 Genome accession   NZ_CP121467
Coordinates   286177..288417 (+) Length   746 a.a.
NCBI ID   WP_000084755.1    Uniprot ID   A0A1X1IBY7
Organism   Streptococcus sp. D7B5     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 281177..293417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS01350 (P8P68_01350) - 281376..283430 (+) 2055 WP_278276025.1 G5 domain-containing protein -
  P8P68_RS01355 (P8P68_01355) ald 283619..284731 (-) 1113 WP_049501030.1 alanine dehydrogenase -
  P8P68_RS01360 (P8P68_01360) - 284907..285476 (+) 570 WP_000443757.1 GNAT family N-acetyltransferase -
  P8P68_RS01365 (P8P68_01365) comEA/celA/cilE 285543..286193 (+) 651 WP_000452009.1 helix-hairpin-helix domain-containing protein Machinery gene
  P8P68_RS01370 (P8P68_01370) comEC/celB 286177..288417 (+) 2241 WP_000084755.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  P8P68_RS01375 (P8P68_01375) infC 288637..289167 (+) 531 WP_000848185.1 translation initiation factor IF-3 -
  P8P68_RS01380 (P8P68_01380) rpmI 289200..289400 (+) 201 WP_001125942.1 50S ribosomal protein L35 -
  P8P68_RS01385 (P8P68_01385) rplT 289452..289811 (+) 360 WP_000124830.1 50S ribosomal protein L20 -
  P8P68_RS01390 (P8P68_01390) - 289987..291651 (+) 1665 WP_278276026.1 molecular chaperone HscC -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 84688.00 Da        Isoelectric Point: 8.8963

>NTDB_id=812199 P8P68_RS01370 WP_000084755.1 286177..288417(+) (comEC/celB) [Streptococcus sp. D7B5]
MSQWIKNFPIPLIYLSFLLLWLYYAILGASYLALLGFVFLLVCLFFQFPWKPAGKVLAICGVFGFWFLFQNWQQTQVSQD
LVGYVEKVRISPDTIKVNGDSLSFRGKAEGHTFQVYYKLQSEEEKELFQTLTDLHEIELEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLTIKSIQSMKQVSSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFVYPVTQFNLVFEWLENIIRLVSQLASRPLVFGQPNAWLLILLLVSLALVYDMRKNIKRLAGFSLFIVGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKVEASKKIEDWQEKATTSNAQRTLIPYLKSRGVDKIDQLILTNTDK
EHIGDLLEVTKAFHIGEILVSKGSLTQKEFVAELEASQTKVRSVTVGDNLLIFGSQLEVLSSRKIGDGDRDASLVLYGKL
LDKHFLFTGNLKEKGEKDLLKHYPDLEVDVLKAGQHGAKTSSNPVFLEKLKPEITLISVGKNNHTKFPHQETLTRLESIK
SKIYRTDQQGAIRFKGWNSWRIETVR

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=812199 P8P68_RS01370 WP_000084755.1 286177..288417(+) (comEC/celB) [Streptococcus sp. D7B5]
ATGTCACAGTGGATTAAGAATTTCCCTATCCCCCTAATCTATCTGAGCTTTCTGTTGCTCTGGCTTTACTATGCCATTTT
AGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTCGTCTGTCTCTTTTTCCAATTTCCTTGGAAACCGGCTG
GAAAAGTTCTAGCGATTTGTGGAGTTTTTGGATTTTGGTTTCTGTTTCAAAACTGGCAACAGACACAAGTGAGTCAAGAC
TTGGTTGGCTATGTTGAAAAGGTGAGGATTTCACCAGATACCATCAAAGTCAATGGGGATAGTCTGTCCTTTCGGGGCAA
GGCTGAGGGTCACACCTTCCAAGTTTACTATAAACTCCAGTCCGAGGAAGAGAAAGAGCTCTTTCAGACCTTAACAGACC
TTCATGAGATTGAACTAGAAGGAAAACTTTCGGAACCCGAAGGGCAGAGGAATTTTGGTGGCTTTAACTACCAAGCCTAT
CTGAAGACTCAAGGAATTTACCAAACTTTGACTATCAAGAGTATCCAGTCAATGAAACAGGTTAGCAGTTGGGATATAGG
AGAAAATCTGTCTAGTTTACGTCGAAAGGCTGTAGTTTGGATCAAGATGCACTTTCCAGATCCTATGCGCAACTATATGA
CAGGTCTTCTTTTAGGACATTTGGACACGGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTTGGAATTATCCATCTC
TTTGCCTTGTCTGGTATGCAGGTGGGCTTCTTTATGGATGCCTTTAAGAAACTCCTCTTACGATTGGGCTTGACTCAAGA
AAAGTTGAAGTGGCTAACCTATCCCTTTTCCCTTATCTATGCAGGTCTGACAGGATTTTCAGCTTCGGTCATTCGTAGTC
TCTTACAAAAGTTACTAGCCCAACATGGTGTTAAGGGCTTGGACAATTTTGCCTTAACAGTCCTTGTCCTCTTTATCATC
ATGCCCAACTTTTTCCTAACAGCAGGAGGAGTCTTGTCTTGCGCTTATGCTTTTATCTTGACCATGACAAGCAAAGAAGG
GGAGGGACTCAAGGCTGTTGCCAGAGAAAGTCTGGTCATTTCTTTGGGAATATTACCCATTCTATCCTTTTATTTTGCAG
AATTTCAGCCTTGGTCTATTCTTTTGACCTTTGTCTTTTCCTTTCTGTTTGATGTGGTCTTCTTACCGCTTTTGTCCATC
TTATTCATCCTGTCTTTTGTTTACCCAGTCACTCAGTTTAACCTTGTCTTTGAGTGGTTGGAGAACATCATTCGCTTGGT
ATCGCAGCTGGCAAGCAGGCCTCTGGTCTTTGGTCAACCCAACGCATGGCTGTTGATTCTACTGTTAGTTTCATTAGCCT
TGGTCTATGACATGAGGAAAAACATCAAAAGACTAGCAGGATTCAGTCTCTTTATTGTGGGGCTCTTTTTCCTGACCAAG
CATCCACTTGAAAATGAAATTACCATGCTGGATGTAGGGCAAGGGGAGAGTATTTTCCTACGGGATGTGACTGGTAAAAC
CATTCTCATAGATGTTGGTGGTAAGGTAGAAGCTAGTAAGAAAATCGAGGACTGGCAAGAAAAGGCGACAACCAGCAATG
CCCAGAGAACCTTGATTCCCTATCTTAAAAGTCGAGGAGTAGACAAGATTGACCAGCTGATTTTGACAAATACAGATAAG
GAGCATATTGGAGATTTGCTGGAGGTGACCAAGGCTTTCCATATCGGGGAGATTTTAGTATCAAAAGGAAGTTTGACACA
GAAGGAATTTGTGGCAGAACTAGAAGCAAGCCAAACCAAGGTACGCAGTGTGACAGTAGGAGATAACTTGCTAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTTCAAGGAAAATTGGAGATGGGGATCGTGATGCTTCCCTGGTTCTTTATGGAAAACTC
TTGGATAAGCACTTTCTCTTCACAGGAAATTTGAAAGAGAAGGGAGAGAAGGACTTGCTGAAGCATTATCCTGACCTAGA
GGTGGATGTCTTGAAAGCGGGCCAACATGGTGCTAAAACCTCATCCAATCCAGTTTTCCTCGAAAAACTCAAACCAGAGA
TTACTCTCATTTCAGTTGGAAAAAACAATCATACGAAATTTCCCCATCAGGAAACCTTGACACGACTGGAAAGTATCAAG
AGTAAGATTTACCGAACTGACCAGCAAGGGGCTATCCGCTTTAAAGGATGGAATAGTTGGAGAATTGAAACGGTTCGATA
A

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-693)

Competence protein (Competence)

(216-458)

Domain of unknown function (DUF4131) (DUF4131)

(29-176)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1IBY7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis NCTC 12261

87.114

99.866

0.87
  comEC/celB Streptococcus mitis SK321

86.997

100

0.87
  comEC/celB Streptococcus pneumoniae TIGR4

86.059

100

0.861
  comEC/celB Streptococcus pneumoniae Rx1

85.523

100

0.855
  comEC/celB Streptococcus pneumoniae D39

85.523

100

0.855
  comEC/celB Streptococcus pneumoniae R6

85.523

100

0.855
  comEC Lactococcus lactis subsp. cremoris KW2

44.939

99.33

0.446