Detailed information NTG0809357

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: LLHP_RS11845
• Genome accession: NZ_CP120921
• Coordinates: 2265067..2266092 (-)
• Length: 341 a.a.
• NCBI ID: WP_050595614.1
• Uniprot ID: A0A1V0PEJ1
• Organism: Lactococcus cremoris subsp. cremoris HP
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2260067..2271092

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLHP_RS11800 (LLHP_11845)	-	2260208..2261017 (-)	810	WP_011677177.1	metal ABC transporter permease	-
LLHP_RS11805 (LLHP_11850)	-	2261010..2261747 (-)	738	WP_011677178.1	metal ABC transporter ATP-binding protein	-
LLHP_RS11810 (LLHP_11855)	-	2261926..2262768 (-)	843	WP_011677179.1	metal ABC transporter solute-binding protein, Zn/Mn family	-
LLHP_RS11815 (LLHP_11860)	-	2262765..2263202 (-)	438	WP_011677180.1	zinc-dependent MarR family transcriptional regulator	-
LLHP_RS11820 (LLHP_11865)	comGG	2263282..2263509 (-)	228	WP_228764408.1	competence protein ComGG	Machinery gene
LLHP_RS11825 (LLHP_11870)	comGF	2263605..2264051 (-)	447	WP_011836043.1	competence type IV pilus minor pilin ComGF	Machinery gene
LLHP_RS11830 (LLHP_11875)	comGE	2264014..2264250 (-)	237	WP_014573335.1	competence type IV pilus minor pilin ComGE	Machinery gene
LLHP_RS11835 (LLHP_11880)	comGD	2264282..2264470 (-)	189	WP_014573336.1	hypothetical protein	Machinery gene
LLHP_RS11840 (LLHP_11885)	comGC	2264672..2265022 (-)	351	WP_050574187.1	competence type IV pilus major pilin ComGC	Machinery gene
LLHP_RS11845 (LLHP_11890)	comGB	2265067..2266092 (-)	1026	WP_050595614.1	competence type IV pilus assembly protein ComGB	Machinery gene
LLHP_RS11850 (LLHP_11895)	comGA	2265992..2266972 (-)	981	WP_032951299.1	competence type IV pilus ATPase ComGA	Machinery gene
LLHP_RS11855 (LLHP_11900)	-	2267087..2270917 (-)	3831	Protein_2310	PolC-type DNA polymerase III	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 38420.20 Da
• Isoelectric Point: 9.9840

>NTDB_id=809357 LLHP_RS11845 WP_050595614.1 2265067..2266092(-) (comGB) [Lactococcus cremoris subsp. cremoris HP]
MQTDILRLLRPKGKKLALIKQAKLIQLMGNLLNNGFHLGEVINFLALSKLVEKEFVFKMHQGLSSGNSLSEILDSLSCSK
NVVTQLALVEVHGNLVGTMQLVELHLKKQLKVKKKLIEVATYPVVLLVFLIGIMWGLKNYLLPQIDKGNNFATLLINHLP
LVFFSVGALIVLLTSLSIIIFKHLSALTNFTFLVKVPLVSSFIRLYLTAYFSREWGNLIAQGVELRQIIELMKKQKIRIF
AEVGIKLDLGLKAGQNFEQAVNHFSIFLPELSLMIEYGAIKDKLGLELSVYADECWEQFFSKIDRLMQLIQPLIFIFVAL
MIVLLYAAMSLPIYSNMGSGI

Nucleotide

• Length: 1026 bp

>NTDB_id=809357 LLHP_RS11845 WP_050595614.1 2265067..2266092(-) (comGB) [Lactococcus cremoris subsp. cremoris HP]
ATGCAAACGGACATCTTACGGCTATTGAGGCCGAAAGGGAAAAAATTAGCATTAATCAAGCAAGCAAAATTGATACAACT
GATGGGGAATCTTTTGAATAATGGTTTCCATTTGGGAGAAGTTATCAATTTTTTAGCTTTATCAAAATTAGTAGAAAAAG
AGTTTGTATTCAAAATGCACCAAGGTCTCAGTTCTGGAAATTCATTATCTGAAATTTTAGATAGTCTCTCTTGTTCTAAA
AATGTTGTGACACAACTTGCTTTGGTAGAAGTGCATGGGAATTTAGTAGGAACCATGCAATTGGTAGAACTGCATTTAAA
AAAGCAGCTTAAGGTCAAAAAGAAATTAATTGAAGTGGCAACTTATCCAGTTGTATTGTTGGTATTTCTCATTGGAATTA
TGTGGGGCTTGAAAAATTATTTATTACCTCAAATTGATAAGGGAAATAATTTTGCTACTTTATTAATTAATCATTTACCG
CTAGTATTTTTTTCTGTTGGTGCTTTAATCGTTTTACTGACAAGTTTATCAATAATAATATTCAAACATCTTTCAGCACT
CACTAATTTTACTTTTTTGGTTAAAGTTCCATTAGTAAGTTCTTTTATCCGCTTGTATTTGACCGCTTATTTCTCCAGAG
AATGGGGAAATTTAATTGCTCAAGGAGTTGAATTGCGACAAATAATAGAATTGATGAAAAAGCAGAAAATTCGCATTTTT
GCGGAAGTTGGAATTAAACTTGATTTGGGTTTGAAGGCTGGTCAGAATTTTGAGCAAGCTGTCAATCATTTTTCGATTTT
TTTACCAGAACTTTCTTTGATGATTGAGTACGGCGCGATTAAAGATAAATTAGGGTTGGAGCTTTCTGTTTATGCTGATG
AATGTTGGGAACAATTCTTTTCTAAGATAGACCGTCTAATGCAATTAATACAACCCCTTATTTTTATTTTTGTTGCTTTG
ATGATTGTCTTATTGTATGCAGCGATGTCGTTACCCATTTATTCTAATATGGGTTCTGGAATTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (211-332)

• Type II secretion system (T2SS), protein F (T2SSF) (25-143)

3D structure

• AlphaFold DB: A0A1V0PEJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Lactococcus lactis subsp. cremoris KW2	97.361	100	0.974
comYB	Streptococcus gordonii str. Challis substr. CH1	51.039	98.827	0.504
comGB/cglB	Streptococcus pneumoniae D39	50.299	97.947	0.493
comGB/cglB	Streptococcus pneumoniae R6	50.299	97.947	0.493
comGB/cglB	Streptococcus pneumoniae Rx1	50.299	97.947	0.493
comGB/cglB	Streptococcus pneumoniae TIGR4	50.299	97.947	0.493
comGB/cglB	Streptococcus mitis SK321	50	97.947	0.49
comGB/cglB	Streptococcus mitis NCTC 12261	49.102	97.947	0.481
comYB	Streptococcus mutans UA140	50.955	92.082	0.469
comYB	Streptococcus mutans UA159	50.318	92.082	0.463