Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   P1T45_RS10885 Genome accession   NZ_CP119427
Coordinates   2066051..2067322 (-) Length   423 a.a.
NCBI ID   WP_003108931.1    Uniprot ID   -
Organism   Streptococcus parauberis strain KSP45     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2056630..2084736 2066051..2067322 within 0


Gene organization within MGE regions


Location: 2056630..2084736
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1T45_RS10830 (P1T45_10835) nrdG 2056630..2057244 (-) 615 WP_003104313.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  P1T45_RS10835 (P1T45_10840) - 2057259..2057753 (-) 495 WP_003108940.1 GNAT family N-acetyltransferase -
  P1T45_RS10840 (P1T45_10845) - 2057734..2058696 (-) 963 WP_003108938.1 Gfo/Idh/MocA family protein -
  P1T45_RS10845 (P1T45_10850) - 2058720..2058869 (-) 150 WP_003108936.1 hypothetical protein -
  P1T45_RS10850 (P1T45_10855) nrdD 2058959..2061148 (-) 2190 WP_003102395.1 anaerobic ribonucleoside-triphosphate reductase -
  P1T45_RS10855 (P1T45_10860) - 2061248..2062806 (-) 1559 Protein_2089 DUF2079 domain-containing protein -
  P1T45_RS10860 (P1T45_10865) - 2062955..2063272 (-) 318 WP_003104776.1 DUF1292 domain-containing protein -
  P1T45_RS10865 (P1T45_10870) ruvX 2063283..2063701 (-) 419 Protein_2091 Holliday junction resolvase RuvX -
  P1T45_RS10870 (P1T45_10875) - 2063698..2063967 (-) 270 WP_003104158.1 IreB family regulatory phosphoprotein -
  P1T45_RS10875 (P1T45_10880) spx 2064081..2064479 (-) 399 WP_003104943.1 transcriptional regulator Spx -
  P1T45_RS10880 (P1T45_10885) recA 2064832..2065971 (-) 1140 WP_003102546.1 recombinase RecA Machinery gene
  P1T45_RS10885 (P1T45_10890) cinA 2066051..2067322 (-) 1272 WP_003108931.1 competence/damage-inducible protein A Machinery gene
  P1T45_RS10890 (P1T45_10895) - 2067711..2068262 (-) 552 WP_096633379.1 DNA-3-methyladenine glycosylase I -
  P1T45_RS10895 (P1T45_10900) ruvA 2068266..2068859 (-) 594 WP_003108930.1 Holliday junction branch migration protein RuvA -
  P1T45_RS10900 (P1T45_10905) - 2068861..2070084 (-) 1224 WP_003103803.1 MFS transporter -
  P1T45_RS10905 (P1T45_10910) mutL 2070095..2072071 (-) 1977 WP_003108928.1 DNA mismatch repair endonuclease MutL -
  P1T45_RS10910 (P1T45_10915) - 2072168..2073313 (-) 1146 WP_003108925.1 site-specific integrase -
  P1T45_RS10915 (P1T45_10920) - 2074019..2074216 (-) 198 Protein_2101 helix-turn-helix domain-containing protein -
  P1T45_RS10920 (P1T45_10925) - 2074334..2074540 (+) 207 WP_003108921.1 helix-turn-helix transcriptional regulator -
  P1T45_RS10925 (P1T45_10930) - 2074800..2075024 (+) 225 WP_003108919.1 hypothetical protein -
  P1T45_RS10930 (P1T45_10935) - 2075012..2075245 (+) 234 WP_003108917.1 hypothetical protein -
  P1T45_RS10935 (P1T45_10940) - 2075258..2075530 (+) 273 WP_003108915.1 AlpA family transcriptional regulator -
  P1T45_RS10940 (P1T45_10945) - 2075540..2076058 (+) 519 WP_233847624.1 hypothetical protein -
  P1T45_RS10945 (P1T45_10950) - 2076201..2077760 (+) 1560 WP_003108911.1 hypothetical protein -
  P1T45_RS10950 (P1T45_10955) - 2078043..2078357 (+) 315 WP_003108909.1 hypothetical protein -
  P1T45_RS10955 (P1T45_10960) - 2078347..2078556 (+) 210 WP_308695474.1 hypothetical protein -
  P1T45_RS10960 (P1T45_10965) - 2078546..2078737 (+) 192 WP_146264510.1 hypothetical protein -
  P1T45_RS10965 (P1T45_10970) - 2078891..2079235 (+) 345 WP_037620317.1 hypothetical protein -
  P1T45_RS10970 (P1T45_10975) - 2079232..2079465 (+) 234 WP_037620315.1 hypothetical protein -
  P1T45_RS10975 (P1T45_10980) - 2079467..2079817 (+) 351 WP_003108903.1 hypothetical protein -
  P1T45_RS10980 (P1T45_10985) - 2079832..2080065 (+) 234 WP_003108902.1 hypothetical protein -
  P1T45_RS10985 (P1T45_10990) - 2080238..2080660 (+) 423 WP_003108901.1 hypothetical protein -
  P1T45_RS10990 (P1T45_10995) - 2080674..2081093 (+) 420 WP_003108900.1 DUF1492 domain-containing protein -
  P1T45_RS10995 (P1T45_11000) - 2081099..2081533 (+) 435 WP_003108899.1 DUF1492 domain-containing protein -
  P1T45_RS11000 (P1T45_11005) - 2081694..2082356 (-) 663 WP_003108897.1 hypothetical protein -
  P1T45_RS11005 (P1T45_11010) - 2082552..2083052 (-) 501 WP_308695475.1 hypothetical protein -
  P1T45_RS11010 (P1T45_11015) - 2083046..2083462 (-) 417 WP_308695478.1 hypothetical protein -
  P1T45_RS11015 (P1T45_11020) - 2084122..2084736 (+) 615 WP_003107889.1 CadD family cadmium resistance transporter -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46135.82 Da        Isoelectric Point: 4.8894

>NTDB_id=799272 P1T45_RS10885 WP_003108931.1 2066051..2067322(-) (cinA) [Streptococcus parauberis strain KSP45]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAEIGVDVYYHTAVGDNEIRLLNILEVASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGLSLVFDREASQKLDQFFSSRSESSRTPNNERQAQLIEGSKPIQNITGLAVGGLIEKAGVTYVVLPGPPSEMKPM
VNQYLLPLLLNEETKLYSRVLRFFGIGESQLVTILADLIANQLDPTIASYAKIGEVTLRLSTKSDSQELAYQKLDQLESQ
IKAISTIDGQLLGDLLYGYGEDNSLARETFQLLKKADKTITAAESLTAGLFQSKIADFPGSSSIFNGGFVTYSIEEKAKM
LEIPFADLQRKGVVSDYTAKQMANQARLLTESDIGVSLTGVAGPDFLEGQQAGTVFIGISTKEKVESYKVLIGGRSRSDV
RYIACLHAFNLVRKTLLNTQNLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=799272 P1T45_RS10885 WP_003108931.1 2066051..2067322(-) (cinA) [Streptococcus parauberis strain KSP45]
ATGAAAGCTGAATTAATTGCAGTCGGAACAGAAATCTTGACCGGTCAAATAGTTAATACGAACGCACAGTTTTTATCAGA
AAAAATGGCAGAGATTGGAGTTGATGTCTATTATCATACAGCAGTAGGCGATAATGAAATCAGATTATTAAATATCCTTG
AAGTTGCAAGTAAACGTAGTGATTTAGTGATATTATGTGGCGGTTTGGGACCTACTGAGGATGATTTGACTAAACAAACG
CTAGCTAAGTTTTTAGGTCTGTCATTGGTCTTTGACAGAGAAGCTAGTCAAAAACTGGACCAATTTTTTTCCTCTCGGTC
TGAGAGTTCTAGAACTCCAAATAATGAGAGGCAAGCACAGTTGATTGAAGGGTCCAAACCTATTCAAAACATTACAGGTC
TAGCTGTTGGTGGTTTAATCGAAAAAGCTGGTGTAACTTATGTCGTCTTACCTGGACCGCCTAGTGAAATGAAACCAATG
GTTAATCAGTATCTACTACCACTGTTGCTGAATGAGGAAACTAAACTCTACTCTCGTGTTTTACGTTTTTTTGGAATTGG
AGAAAGCCAATTAGTTACTATTTTAGCTGATCTTATTGCAAATCAATTAGACCCAACAATTGCTTCCTATGCCAAAATCG
GCGAGGTAACATTGCGCTTGTCAACTAAGTCTGATTCTCAAGAGCTAGCTTATCAAAAATTGGATCAATTAGAAAGTCAG
ATTAAGGCCATTTCAACTATAGATGGACAATTATTAGGAGACTTATTATATGGATATGGTGAGGATAATAGCCTGGCGCG
TGAGACTTTCCAGTTGTTAAAAAAAGCAGATAAGACAATTACAGCTGCAGAAAGTTTAACAGCAGGGCTATTCCAATCTA
AAATTGCTGATTTTCCAGGGTCATCCAGTATTTTTAACGGTGGATTTGTTACCTATAGTATCGAAGAAAAGGCAAAAATG
TTAGAGATTCCATTTGCTGATTTACAACGAAAAGGTGTTGTTAGTGATTATACTGCTAAACAAATGGCTAATCAAGCACG
ACTCTTAACTGAAAGTGATATTGGTGTTAGCTTAACTGGCGTTGCTGGTCCGGATTTCTTGGAAGGACAACAAGCAGGAA
CAGTTTTTATTGGTATTTCGACAAAAGAAAAAGTAGAATCATATAAGGTACTAATTGGCGGCAGGAGTCGCTCAGATGTC
AGATATATAGCTTGCTTACATGCCTTCAACCTAGTCCGAAAAACTTTATTAAATACCCAAAATTTGTTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-244)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

70.813

98.818

0.7
  cinA Streptococcus mutans UA159

69.74

100

0.697
  cinA Streptococcus mitis NCTC 12261

70.574

98.818

0.697
  cinA Streptococcus pneumoniae TIGR4

69.617

98.818

0.688
  cinA Streptococcus pneumoniae Rx1

69.378

98.818

0.686
  cinA Streptococcus pneumoniae R6

69.378

98.818

0.686
  cinA Streptococcus pneumoniae D39

69.139

98.818

0.683
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

46.172

98.818

0.456