Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   PYH61_RS06290 Genome accession   NZ_CP118776
Coordinates   1227670..1227987 (+) Length   105 a.a.
NCBI ID   WP_070045385.1    Uniprot ID   A0AAX3W128
Organism   Mammaliicoccus lentus strain 7074     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1222670..1232987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYH61_RS06250 (PYH61_06250) - 1222794..1222985 (+) 192 WP_017000229.1 YqgQ family protein -
  PYH61_RS06255 (PYH61_06255) - 1222982..1223953 (+) 972 WP_239724182.1 ROK family glucokinase -
  PYH61_RS06260 (PYH61_06260) - 1223953..1224267 (+) 315 WP_017000231.1 MTH1187 family thiamine-binding protein -
  PYH61_RS06265 (PYH61_06265) - 1224297..1224536 (-) 240 WP_017000232.1 DUF2759 domain-containing protein -
  PYH61_RS06270 (PYH61_06270) - 1224634..1225266 (+) 633 WP_017000233.1 MBL fold metallo-hydrolase -
  PYH61_RS06275 (PYH61_06275) - 1225331..1225579 (-) 249 WP_017000234.1 DUF2626 family protein -
  PYH61_RS06280 (PYH61_06280) comGA 1225732..1226628 (+) 897 WP_135031058.1 competence type IV pilus ATPase ComGA Machinery gene
  PYH61_RS06285 (PYH61_06285) comGB 1226625..1227665 (+) 1041 WP_239724184.1 competence type IV pilus assembly protein ComGB -
  PYH61_RS06290 (PYH61_06290) comGC 1227670..1227987 (+) 318 WP_070045385.1 competence type IV pilus major pilin ComGC Machinery gene
  PYH61_RS06295 (PYH61_06295) comGD 1227987..1228415 (+) 429 WP_017000239.1 competence type IV pilus minor pilin ComGD -
  PYH61_RS06300 (PYH61_06300) comGE 1228399..1228674 (+) 276 WP_017000240.1 competence type IV pilus minor pilin ComGE -
  PYH61_RS06305 (PYH61_06305) comGF 1228688..1229083 (+) 396 WP_239724188.1 competence type IV pilus minor pilin ComGF -
  PYH61_RS06310 (PYH61_06310) - 1229319..1229837 (+) 519 WP_064205405.1 shikimate kinase -
  PYH61_RS06315 (PYH61_06315) gcvT 1230000..1231088 (+) 1089 WP_103269518.1 glycine cleavage system aminomethyltransferase GcvT -
  PYH61_RS06320 (PYH61_06320) gcvPA 1231100..1232443 (+) 1344 WP_103269519.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence


Protein


Download         Length: 105 a.a.        Molecular weight: 11590.66 Da        Isoelectric Point: 7.8266

>NTDB_id=795164 PYH61_RS06290 WP_070045385.1 1227670..1227987(+) (comGC) [Mammaliicoccus lentus strain 7074]
MKNIKFFKKEEGFTLIEMLIVLLIISILLIIIIPNISKQSETVKSTGCQAQVKMVAGQVEAYTLKHDAKPNSINDLVSDG
FIKENQLTCKSGQNIVLNNGEVVAQ

Nucleotide


Download         Length: 318 bp        

>NTDB_id=795164 PYH61_RS06290 WP_070045385.1 1227670..1227987(+) (comGC) [Mammaliicoccus lentus strain 7074]
ATGAAAAATATAAAGTTTTTTAAAAAAGAAGAAGGCTTCACGTTGATTGAGATGTTAATCGTATTATTAATTATAAGTAT
TTTACTTATAATTATAATCCCTAACATAAGCAAGCAGTCTGAAACCGTGAAAAGTACTGGTTGTCAGGCACAAGTTAAAA
TGGTTGCTGGCCAAGTAGAAGCATATACATTAAAACACGATGCTAAGCCAAATTCAATTAATGATTTAGTAAGTGATGGG
TTCATAAAAGAGAATCAATTGACTTGTAAATCTGGTCAGAACATTGTTTTAAATAACGGAGAAGTAGTAGCTCAATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus MW2

66.337

96.19

0.638

  comGC Staphylococcus aureus N315

66.337

96.19

0.638

  comGC Bacillus subtilis subsp. subtilis str. 168

46.237

88.571

0.41

  comGC/cglC Streptococcus mitis NCTC 12261

40.952

100

0.41

  comGC/cglC Streptococcus mitis SK321

43.299

92.381

0.4

  comGC/cglC Streptococcus pneumoniae R6

44.828

82.857

0.371

  comGC/cglC Streptococcus pneumoniae TIGR4

44.828

82.857

0.371

  comGC/cglC Streptococcus pneumoniae Rx1

44.828

82.857

0.371

  comGC/cglC Streptococcus pneumoniae D39

44.828

82.857

0.371

  comYC Streptococcus mutans UA159

50.649

73.333

0.371

  comYC Streptococcus mutans UA140

50.649

73.333

0.371

  comGC Lactococcus lactis subsp. cremoris KW2

46.341

78.095

0.362