Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PW252_RS00345 Genome accession   NZ_CP118735
Coordinates   60399..61580 (+) Length   393 a.a.
NCBI ID   WP_248051106.1    Uniprot ID   A0AA96VJV5
Organism   Streptococcus iners strain 29887     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 55399..66580
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS00320 (PW252_00320) mutL 55838..57775 (+) 1938 WP_248051111.1 DNA mismatch repair endonuclease MutL -
  PW252_RS00325 (PW252_00325) - 57849..58214 (+) 366 WP_222338894.1 helix-turn-helix domain-containing protein -
  PW252_RS00330 (PW252_00330) - 58229..58876 (+) 648 WP_248051110.1 CPBP family intramembrane glutamic endopeptidase -
  PW252_RS00335 (PW252_00335) ruvA 58955..59545 (+) 591 WP_248051109.1 Holliday junction branch migration protein RuvA -
  PW252_RS00340 (PW252_00340) - 59772..60329 (+) 558 WP_248051108.1 DNA-3-methyladenine glycosylase I -
  PW252_RS00345 (PW252_00345) cinA 60399..61580 (+) 1182 WP_248051106.1 competence/damage-inducible protein A Machinery gene
  PW252_RS00350 (PW252_00350) recA 61632..62783 (+) 1152 WP_105125513.1 recombinase RecA Machinery gene
  PW252_RS00355 (PW252_00355) spx 62943..63341 (+) 399 WP_029177692.1 transcriptional regulator Spx -
  PW252_RS00360 (PW252_00360) - 63447..63713 (+) 267 WP_029177693.1 IreB family regulatory phosphoprotein -
  PW252_RS00365 (PW252_00365) ruvX 63713..64132 (+) 420 WP_032499507.1 Holliday junction resolvase RuvX -
  PW252_RS00370 (PW252_00370) - 64144..64461 (+) 318 WP_004195480.1 DUF1292 domain-containing protein -
  PW252_RS00375 (PW252_00375) - 64848..65396 (+) 549 WP_136628856.1 nucleotidyltransferase family protein -
  PW252_RS00380 (PW252_00380) comX/sigX 65482..65955 (+) 474 WP_248051104.1 sigma-70 family RNA polymerase sigma factor Regulator
  PW252_RS00385 (PW252_00385) rpsJ 66220..66528 (+) 309 WP_002939332.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42878.82 Da        Isoelectric Point: 4.6513

>NTDB_id=794710 PW252_RS00345 WP_248051106.1 60399..61580(+) (cinA) [Streptococcus iners strain 29887]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLELASKRSEIVILCGGLGPTEDDLTKQT
LAAFLGRKLVFDEKAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGLIEQAGVTYVVLPGPPSELRAM
FTESLQPLLNQSSQQLYSRVLRFFGIGESQLVTILADLIDKQTDPTLAPYAKVGEVTLRLSTKANSQEEADFRLNQLEED
ILQRDKLREYFYAYGEKNSLVQTVAERLVEKNKSIAIVEQGTGGLLQSEVSLALAGQPYFSGGKVIGQLGTKSGRCSEEA
DGIREELQADLGLAVSVLIKPESTEDNVLVKVYLALADTSGISQKEVDLGGYSWQHIRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=794710 PW252_RS00345 WP_248051106.1 60399..61580(+) (cinA) [Streptococcus iners strain 29887]
ATGAAAGCAGAACTAATTGCCGTCGGGACGGAGATTTTAACAGGACAAATCGTTAATACCAATGCCCAGTTCCTTTCGGA
GAAATGCGCAGAGCTGGGAATTGATGTTTACTTCCACACAGCTGTTGGAGATAATGAACAGAGGCTTTTATCTGTACTGG
AGTTAGCCAGCAAGCGTAGTGAGATAGTTATTCTCTGTGGAGGACTGGGGCCAACAGAAGATGACTTGACTAAGCAGACC
TTGGCAGCCTTCTTAGGTAGAAAATTGGTCTTTGATGAAAAAGCCATGGCAAAATTAGACCGCTTTTTTGCCAGCCGACC
AGGTCGTGTCCGCACGCCCAACAATGAGCGCCAAGCACAAATCGTTGAGGGAAGTCAGGCTTTGCAAAATCCAGCTGGTT
TGGCAGTAGGAGGCTTGATTGAGCAAGCTGGAGTGACCTATGTTGTCTTACCTGGTCCTCCAAGTGAACTTAGAGCCATG
TTTACAGAAAGTTTACAACCTTTGCTTAACCAGTCAAGTCAGCAACTCTATTCTCGTGTTCTACGCTTTTTTGGTATTGG
CGAAAGTCAGTTGGTGACGATTTTAGCTGATTTGATTGACAAACAAACTGACCCAACTCTTGCCCCCTATGCCAAGGTTG
GTGAAGTGACCTTGCGCTTGTCCACCAAGGCAAACAGTCAAGAAGAAGCAGATTTCCGTCTGAATCAGTTGGAAGAAGAC
ATCTTACAACGTGATAAACTGAGAGAATATTTCTATGCTTACGGTGAGAAAAATAGTCTAGTACAGACAGTAGCAGAGCG
ATTGGTGGAAAAGAATAAAAGCATAGCTATCGTCGAACAGGGAACAGGCGGACTTTTACAGTCAGAAGTCAGCTTGGCTT
TGGCTGGGCAACCTTATTTTAGCGGTGGAAAAGTCATCGGTCAGTTAGGTACAAAATCGGGCAGGTGCTCAGAAGAAGCT
GATGGCATTCGTGAGGAGCTACAGGCTGATTTGGGACTGGCTGTGTCGGTACTTATCAAGCCTGAGTCGACAGAGGATAA
CGTTCTTGTAAAGGTATATCTAGCCTTGGCTGACACCTCTGGCATTTCCCAAAAAGAGGTTGACTTGGGTGGCTACTCCT
GGCAACACATCCGCCAATTAGCTTGCTTGCAAGCCTTAGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(308-393)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

87.023

100

0.87
  cinA Streptococcus mitis SK321

56.731

100

0.601
  cinA Streptococcus pneumoniae TIGR4

56.49

100

0.598
  cinA Streptococcus mitis NCTC 12261

56.49

100

0.598
  cinA Streptococcus pneumoniae Rx1

56.49

100

0.598
  cinA Streptococcus pneumoniae R6

56.49

100

0.598
  cinA Streptococcus pneumoniae D39

56.25

100

0.595
  cinA Streptococcus mutans UA159

55.961

100

0.585
  cinA Bacillus subtilis subsp. subtilis str. 168

41.91

95.929

0.402