Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   MGCS35922_RS00795 Genome accession   NZ_CP118097
Coordinates   128666..128992 (+) Length   108 a.a.
NCBI ID   WP_084916953.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 94056..127697 128666..128992 flank 969


Gene organization within MGE regions


Location: 94056..128992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGCS35922_RS00650 (MGCS35922_00266) - 94056..95189 (-) 1134 WP_001007677.1 site-specific integrase -
  MGCS35922_RS00655 (MGCS35922_00268) - 95194..95388 (-) 195 WP_000562208.1 DUF3173 family protein -
  MGCS35922_RS00660 (MGCS35922_00270) - 95457..96803 (-) 1347 WP_084916941.1 Rep family protein -
  MGCS35922_RS00665 (MGCS35922_00272) - 97154..97513 (-) 360 WP_025194534.1 hypothetical protein -
  MGCS35922_RS00670 (MGCS35922_00274) - 97528..97866 (-) 339 WP_000092752.1 hypothetical protein -
  MGCS35922_RS00675 (MGCS35922_00276) - 98116..98571 (+) 456 WP_000021848.1 helix-turn-helix domain-containing protein -
  MGCS35922_RS00680 (MGCS35922_00278) - 98869..99998 (+) 1130 Protein_85 IS3 family transposase -
  MGCS35922_RS00685 (MGCS35922_00280) - 100086..100418 (-) 333 WP_000181338.1 hypothetical protein -
  MGCS35922_RS00690 (MGCS35922_00282) - 100429..100836 (-) 408 WP_000351058.1 helix-turn-helix transcriptional regulator -
  MGCS35922_RS00695 - 101092..101406 (+) 315 Protein_88 transposase -
  MGCS35922_RS00700 (MGCS35922_00286) - 101826..102362 (+) 537 WP_041788713.1 NUDIX domain-containing protein -
  MGCS35922_RS00705 (MGCS35922_00288) - 102497..103396 (+) 900 WP_003058398.1 prenyltransferase -
  MGCS35922_RS00710 (MGCS35922_00290) - 103411..104619 (+) 1209 WP_065358554.1 NAD(P)/FAD-dependent oxidoreductase -
  MGCS35922_RS00715 (MGCS35922_00292) - 104729..106156 (+) 1428 WP_084916943.1 cytochrome ubiquinol oxidase subunit I -
  MGCS35922_RS00720 (MGCS35922_00294) cydB 106157..107176 (+) 1020 WP_084916945.1 cytochrome d ubiquinol oxidase subunit II -
  MGCS35922_RS00725 (MGCS35922_00296) cydD 107176..108891 (+) 1716 WP_003055281.1 thiol reductant ABC exporter subunit CydD -
  MGCS35922_RS00730 (MGCS35922_00298) cydC 108888..110636 (+) 1749 WP_065355135.1 thiol reductant ABC exporter subunit CydC -
  MGCS35922_RS00735 (MGCS35922_00300) - 110701..111681 (-) 981 WP_084916947.1 polyprenyl synthetase family protein -
  MGCS35922_RS00740 (MGCS35922_00302) ispE 111937..112788 (+) 852 WP_003061506.1 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase -
  MGCS35922_RS00745 (MGCS35922_00304) - 112857..113300 (+) 444 WP_012766439.1 zinc-dependent MarR family transcriptional regulator -
  MGCS35922_RS00750 (MGCS35922_00306) - 113304..114023 (+) 720 WP_022554112.1 metal ABC transporter ATP-binding protein -
  MGCS35922_RS00755 (MGCS35922_00308) - 114016..114828 (+) 813 WP_003055293.1 metal ABC transporter permease -
  MGCS35922_RS00760 (MGCS35922_00310) tyrS 114877..116133 (-) 1257 WP_084916949.1 tyrosine--tRNA ligase -
  MGCS35922_RS00765 (MGCS35922_00312) pbp1b 116240..118540 (+) 2301 WP_003059682.1 penicillin-binding protein PBP1B -
  MGCS35922_RS00770 (MGCS35922_00316) rpoB 118804..122370 (+) 3567 WP_049519675.1 DNA-directed RNA polymerase subunit beta -
  MGCS35922_RS00775 (MGCS35922_00318) rpoC 122466..126107 (+) 3642 WP_037589802.1 DNA-directed RNA polymerase subunit beta' -
  MGCS35922_RS00780 (MGCS35922_00320) - 126310..126675 (+) 366 WP_003055257.1 DUF1033 family protein -
  MGCS35922_RS00785 (MGCS35922_00322) comGA/cglA 126756..127697 (+) 942 WP_014611930.1 competence type IV pilus ATPase ComGA Machinery gene
  MGCS35922_RS00790 (MGCS35922_00324) comYB 127633..128664 (+) 1032 WP_084916952.1 competence type IV pilus assembly protein ComGB Machinery gene
  MGCS35922_RS00795 (MGCS35922_00326) comYC 128666..128992 (+) 327 WP_084916953.1 competence type IV pilus major pilin ComGC Machinery gene

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12439.42 Da        Isoelectric Point: 9.2972

>NTDB_id=790079 MGCS35922_RS00795 WP_084916953.1 128666..128992(+) (comYC) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
MKNQWKPLRQYQLQAFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLQQLKD
DGSITDKQVKAYTDYYGKHRDETQKLQP

Nucleotide


Download         Length: 327 bp        

>NTDB_id=790079 MGCS35922_RS00795 WP_084916953.1 128666..128992(+) (comYC) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
ATGAAAAACCAATGGAAACCATTACGGCAATACCAACTACAAGCTTTCACACTTCTAGAAATGTTACTGGTGATTTTAGT
CATCAGTGTCTTAATGCTCTTATTTGTACCTAATTTAAGCAAACAAAAAGATAGGGTTACCGAAACAGGAAATGCTGCTG
TTGTCAAATTAGTGGAGAATCAAGCAGAGTTGTACGAATTATCGCAAGGATCAAAACCAAGTTTACAACAGTTGAAAGAC
GATGGCAGTATTACAGATAAACAGGTAAAAGCTTACACAGACTATTATGGAAAACACAGAGATGAAACTCAAAAACTACA
ACCTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

58.095

97.222

0.565
  comGC/cglC Streptococcus mitis SK321

52.83

98.148

0.519
  comGC/cglC Streptococcus pneumoniae D39

51.887

98.148

0.509
  comGC/cglC Streptococcus pneumoniae R6

51.887

98.148

0.509
  comGC/cglC Streptococcus pneumoniae Rx1

51.887

98.148

0.509
  comGC/cglC Streptococcus pneumoniae TIGR4

51.402

99.074

0.509
  comGC Lactococcus lactis subsp. cremoris KW2

53.398

95.37

0.509
  comGC/cglC Streptococcus mitis NCTC 12261

55.102

90.741

0.5
  comYC Streptococcus mutans UA140

52.475

93.519

0.491
  comYC Streptococcus mutans UA159

52.475

93.519

0.491
  comYC Streptococcus suis isolate S10

50.562

82.407

0.417