Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PSC79_RS12645 Genome accession   NZ_CP117511
Coordinates   2627844..2629088 (-) Length   414 a.a.
NCBI ID   WP_010824271.1    Uniprot ID   -
Organism   Enterococcus faecalis strain CQNBZ21-135     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2622844..2634088
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PSC79_RS12625 (PSC79_12655) - 2623314..2623700 (-) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -
  PSC79_RS12630 (PSC79_12660) - 2623774..2624571 (-) 798 WP_085345048.1 TIGR00282 family metallophosphoesterase -
  PSC79_RS12635 (PSC79_12665) rny 2624731..2626287 (-) 1557 WP_002354863.1 ribonuclease Y -
  PSC79_RS12640 (PSC79_12670) recA 2626684..2627730 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  PSC79_RS12645 (PSC79_12675) cinA 2627844..2629088 (-) 1245 WP_010824271.1 competence/damage-inducible protein A Machinery gene
  PSC79_RS12650 (PSC79_12680) - 2629280..2630479 (+) 1200 WP_002370127.1 hypothetical protein -
  PSC79_RS12655 (PSC79_12685) - 2630559..2631188 (-) 630 WP_002354854.1 NAD(P)-dependent oxidoreductase -
  PSC79_RS12660 (PSC79_12690) - 2631247..2631672 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  PSC79_RS12665 (PSC79_12695) - 2631761..2632144 (-) 384 WP_002354850.1 YccF domain-containing protein -
  PSC79_RS12670 (PSC79_12700) - 2632308..2633099 (+) 792 WP_002354848.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45177.29 Da        Isoelectric Point: 4.6698

>NTDB_id=786159 PSC79_RS12645 WP_010824271.1 2627844..2629088(-) (cinA) [Enterococcus faecalis strain CQNBZ21-135]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGATSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKILAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=786159 PSC79_RS12645 WP_010824271.1 2627844..2629088(-) (cinA) [Enterococcus faecalis strain CQNBZ21-135]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGGGCAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGGGAATCCCAGCTGGTGACTGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCCGGAGAAGAATTATTAACAGCGACGGAA
GAAAAGATTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTTACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACTGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGGGGGTTAGATCTTTTACGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.632

100

0.531
  cinA Streptococcus mitis SK321

51.773

100

0.529
  cinA Streptococcus mitis NCTC 12261

51.537

100

0.527
  cinA Streptococcus pneumoniae TIGR4

50.827

100

0.519
  cinA Streptococcus pneumoniae D39

50.591

100

0.517
  cinA Streptococcus pneumoniae R6

50.355

100

0.514
  cinA Streptococcus pneumoniae Rx1

50.355

100

0.514
  cinA Bacillus subtilis subsp. subtilis str. 168

48.768

98.068

0.478
  cinA Streptococcus suis isolate S10

44.282

99.275

0.44