Detailed information NTG0784618

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: IL310_RS02870
• Genome accession: NZ_CP117409
• Coordinates: 174639..175712 (+)
• Length: 357 a.a.
• NCBI ID: WP_201248649.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain LB7
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 169639..180712

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IL310_RS02865 (IL310_02870)	comGA	173807..174745 (+)	939	WP_058206479.1	competence type IV pilus ATPase ComGA	Machinery gene
IL310_RS02870 (IL310_02875)	comGB	174639..175712 (+)	1074	WP_201248649.1	competence type IV pilus assembly protein ComGB	Machinery gene
IL310_RS02875 (IL310_02880)	comGC	175726..176109 (+)	384	WP_012898622.1	competence type IV pilus major pilin ComGC	Machinery gene
IL310_RS02880 (IL310_02885)	comGD	176069..176500 (+)	432	WP_012898621.1	competence type IV pilus minor pilin ComGD	Machinery gene
IL310_RS02885 (IL310_02890)	comGE	176472..176768 (+)	297	WP_033900709.1	competence type IV pilus minor pilin ComGE	Machinery gene
IL310_RS02890 (IL310_02895)	comGF	176731..177177 (+)	447	WP_201248646.1	competence type IV pilus minor pilin ComGF	Machinery gene
IL310_RS02895 (IL310_02900)	comGG	177216..177500 (+)	285	WP_025017139.1	competence type IV pilus minor pilin ComGG	Machinery gene
IL310_RS02900 (IL310_02905)	-	177582..178019 (+)	438	WP_201248645.1	zinc-dependent MarR family transcriptional regulator	-
IL310_RS02905 (IL310_02910)	-	178016..178858 (+)	843	WP_015427160.1	metal ABC transporter substrate-binding protein	-
IL310_RS02910 (IL310_02915)	-	179035..179772 (+)	738	WP_201248644.1	metal ABC transporter ATP-binding protein	-
IL310_RS02915 (IL310_02920)	-	179765..180574 (+)	810	WP_014570791.1	metal ABC transporter permease	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 40354.56 Da
• Isoelectric Point: 10.3000

>NTDB_id=784618 IL310_RS02870 WP_201248649.1 174639..175712(+) (comGB) [Lactococcus lactis strain LB7]
MSLGHQKIGIKKLISYLQMDISHLLKPKGKKLRLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLA
SGQVLSELLESLSFSKNVVTQLALVEVHGNLSGTMQLVELHLKKQLKVKNKLVEVATYPILLLIFLIGIIWGLKNYLLPQ
LNSGSNFATLLINHLPLVFFSFGAFIFLLTALSVTLFKRKSAIMNFTFLVKLPLVHSFIRLYLTAYFAREWGNLIAQGVE
LRQIINLMKKQKSRIFSEVGKNLDLELNAGRSFEQAVSKLALFLPELSLMIEYGAIKDKLGLELSLYADECWEQFFTKID
RLMQLIQPLVFIFVALMIILLYAAMLLPIYSNMGSGI

Nucleotide

• Length: 1074 bp

>NTDB_id=784618 IL310_RS02870 WP_201248649.1 174639..175712(+) (comGB) [Lactococcus lactis strain LB7]
TTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTACTTACAAATGGATATCTCACACCTACTGAAGCC
AAAAGGGAAAAAATTAAGACTGATTAAACAAGCCAAACTTATCCAACTGATGGGAAATCTTTTGAATAGTGGATTTAATT
TAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTACATTAAAAATGAAAGAAGGTCTCGCT
TCTGGTCAAGTTTTATCAGAGCTTTTAGAAAGTCTTTCATTTTCTAAAAATGTGGTGACACAACTTGCTTTGGTAGAAGT
GCATGGTAACTTGTCAGGGACGATGCAATTGGTTGAACTTCATCTAAAAAAACAGCTTAAAGTTAAAAATAAATTAGTGG
AAGTTGCTACTTATCCAATATTGTTATTAATTTTTCTGATTGGAATTATATGGGGCTTAAAAAATTATTTACTACCACAA
CTCAATAGTGGCAGTAACTTTGCTACTCTATTGATTAATCATTTACCCTTAGTATTTTTTTCGTTTGGAGCTTTTATATT
TTTACTGACAGCTTTGTCAGTAACTCTTTTTAAACGAAAATCAGCAATAATGAATTTTACATTTCTTGTTAAATTACCTC
TGGTTCATTCTTTTATCCGTTTATATTTAACAGCTTACTTTGCAAGAGAATGGGGAAATCTAATTGCTCAAGGTGTTGAA
TTACGTCAAATTATTAACTTGATGAAAAAACAAAAAAGTCGAATTTTTTCAGAAGTTGGCAAGAATCTTGATTTAGAATT
GAATGCTGGTCGGTCTTTTGAACAAGCTGTCAGTAAACTTGCGCTTTTTTTACCCGAGCTCTCGTTAATGATTGAATATG
GAGCTATTAAAGATAAATTAGGCTTAGAGCTTTCGCTTTATGCGGATGAATGTTGGGAACAATTTTTTACAAAGATAGAT
CGTTTAATGCAATTAATCCAACCTCTTGTTTTTATTTTCGTAGCATTGATGATTATTTTGCTATATGCAGCCATGTTACT
CCCCATCTATTCAAATATGGGTTCGGGAATATAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (41-159)

• Type II secretion system (T2SS), protein F (T2SSF) (227-348)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Lactococcus lactis subsp. cremoris KW2	83.578	95.518	0.798
comYB	Streptococcus gordonii str. Challis substr. CH1	53.079	95.518	0.507
comYB	Streptococcus mutans UA140	52.786	95.518	0.504
comYB	Streptococcus mutans UA159	52.493	95.518	0.501
comGB/cglB	Streptococcus mitis SK321	51.045	93.838	0.479
comGB/cglB	Streptococcus pneumoniae Rx1	50.746	93.838	0.476
comGB/cglB	Streptococcus pneumoniae D39	50.746	93.838	0.476
comGB/cglB	Streptococcus pneumoniae R6	50.746	93.838	0.476
comGB/cglB	Streptococcus pneumoniae TIGR4	50.746	93.838	0.476
comGB/cglB	Streptococcus mitis NCTC 12261	50.149	93.838	0.471