Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   MGCS36083_RS10525 Genome accession   NZ_CP117285
Coordinates   2128945..2130216 (-) Length   423 a.a.
NCBI ID   WP_003058772.1    Uniprot ID   A0A9X8T4Y6
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2123945..2135216
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGCS36083_RS10495 (MGCS36083_04262) - 2124001..2125563 (-) 1563 WP_084916280.1 DUF2079 domain-containing protein -
  MGCS36083_RS10500 (MGCS36083_04266) - 2125899..2126204 (-) 306 WP_003058733.1 DUF1292 domain-containing protein -
  MGCS36083_RS10505 (MGCS36083_04268) ruvX 2126215..2126634 (-) 420 WP_003053103.1 Holliday junction resolvase RuvX -
  MGCS36083_RS10510 (MGCS36083_04270) - 2126631..2126900 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  MGCS36083_RS10515 (MGCS36083_04274) spx 2127012..2127410 (-) 399 WP_003053105.1 transcriptional regulator Spx -
  MGCS36083_RS10520 (MGCS36083_04278) recA 2127704..2128840 (-) 1137 WP_003058758.1 recombinase RecA Machinery gene
  MGCS36083_RS10525 (MGCS36083_04280) cinA 2128945..2130216 (-) 1272 WP_003058772.1 competence/damage-inducible protein A Machinery gene
  MGCS36083_RS10530 (MGCS36083_04282) - 2130340..2130693 (-) 354 WP_003058738.1 VOC family protein -
  MGCS36083_RS10535 (MGCS36083_04284) - 2130696..2131268 (-) 573 WP_003058799.1 DNA-3-methyladenine glycosylase I -
  MGCS36083_RS10540 (MGCS36083_04286) ruvA 2131278..2131871 (-) 594 WP_003058778.1 Holliday junction branch migration protein RuvA -
  MGCS36083_RS10545 (MGCS36083_04288) - 2131873..2133093 (-) 1221 WP_084916281.1 MDR family MFS transporter -
  MGCS36083_RS10550 (MGCS36083_04290) mutL 2133104..2135086 (-) 1983 WP_012767642.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46007.41 Da        Isoelectric Point: 4.7637

>NTDB_id=783235 MGCS36083_RS10525 WP_003058772.1 2128945..2130216(-) (cinA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083]
MKAELITVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLVFEEQASQKLDAFYASRKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNEVTYVVLPGPPSELKPM
VNEELLPFLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAENQTLADTKLDPLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFSGASQVFNGGFVTYSMEEKARM
LGIPLEDLISHGVVSAYTAEKMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=783235 MGCS36083_RS10525 WP_003058772.1 2128945..2130216(-) (cinA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083]
ATGAAAGCTGAACTGATTACAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGATAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGTGGTCTTGGCCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATATCTTAATAGAGATTTGGTCTTTGAAGAACAAGCTAGTCAAAAATTGGACGCTTTTTATGCTAGTCGTAA
AGAGTCGTCTCGAACGGCAAATAATGCTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TTGCAGTGGGTGGCTTAATCACTGTTAATGAGGTGACTTATGTTGTTTTACCCGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTTTTTTGTCCACACAATCTCGCAAACTTTATTCGAGAGTTTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGATCCTACTATTGCACCTTATGCCAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAATCAAACATTAGCAGATACGAAATTAGATCCACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGGGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACTGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTTCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAGAATG
CTAGGCATTCCTTTAGAGGATTTGATATCGCATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.577

100

0.726
  cinA Streptococcus mitis SK321

70.983

98.582

0.7
  cinA Streptococcus mitis NCTC 12261

70.024

98.582

0.69
  cinA Streptococcus pneumoniae TIGR4

69.784

98.582

0.688
  cinA Streptococcus pneumoniae Rx1

69.784

98.582

0.688
  cinA Streptococcus pneumoniae R6

69.784

98.582

0.688
  cinA Streptococcus pneumoniae D39

69.544

98.582

0.686
  cinA Streptococcus suis isolate S10

52.644

98.345

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

98.818

0.449