Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   PO908_RS05520 Genome accession   NZ_CP117042
Coordinates   1052395..1053237 (-) Length   280 a.a.
NCBI ID   WP_057489665.1    Uniprot ID   A0AAP6BNZ5
Organism   Streptococcus anginosus strain CGMH_KH1     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1047395..1058237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PO908_RS05505 (PO908_05485) trmFO 1048147..1049481 (-) 1335 WP_021001695.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  PO908_RS05510 (PO908_05490) - 1049655..1050152 (-) 498 WP_021001696.1 hypothetical protein -
  PO908_RS05515 (PO908_05495) topA 1050216..1052309 (-) 2094 WP_145747934.1 type I DNA topoisomerase -
  PO908_RS05520 (PO908_05500) dprA/cilB/dalA 1052395..1053237 (-) 843 WP_057489665.1 DNA-processing protein DprA Machinery gene
  PO908_RS05525 (PO908_05505) - 1053321..1053878 (-) 558 WP_057489666.1 sugar O-acetyltransferase -
  PO908_RS05530 (PO908_05510) - 1053868..1054695 (-) 828 WP_021001700.1 PRD domain-containing protein -
  PO908_RS05535 (PO908_05515) - 1054692..1055474 (-) 783 WP_003024460.1 ribonuclease HII -
  PO908_RS05540 (PO908_05520) ylqF 1055461..1056312 (-) 852 WP_003024457.1 ribosome biogenesis GTPase YlqF -
  PO908_RS05545 (PO908_05525) - 1056432..1057349 (-) 918 WP_003024454.1 MBL fold metallo-hydrolase -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31115.60 Da        Isoelectric Point: 5.2196

>NTDB_id=782256 PO908_RS05520 WP_057489665.1 1052395..1053237(-) (dprA/cilB/dalA) [Streptococcus anginosus strain CGMH_KH1]
MDNFDIYKLKEAGLTNQQVINVLSYAEIQEKELSVKDMAVVSECRNPALFIEKYLQLDDDLLRQEFEKFSSFSILDDVYP
WDLSEIYNPPVLLFYKGNLDLLKLPKVAVVGSRNSSRVGSQSVQKIIKELNNELVIVSGLARGIDTSAHMAALQNGGRTI
AVIGTGLDVFYPRANKKLQSYLGEHHLVLSEYGSEAEPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGRSDGCHHLIQEGAKCVTSGADVLSEFQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=782256 PO908_RS05520 WP_057489665.1 1052395..1053237(-) (dprA/cilB/dalA) [Streptococcus anginosus strain CGMH_KH1]
ATGGATAATTTTGATATTTATAAATTAAAAGAAGCTGGCTTGACTAATCAGCAGGTCATCAATGTTCTCTCGTATGCTGA
GATACAAGAAAAAGAATTATCGGTAAAAGATATGGCAGTTGTTTCGGAATGCCGCAATCCTGCTCTTTTCATTGAAAAAT
ATCTGCAGCTAGATGATGATTTATTACGTCAAGAATTTGAAAAGTTCTCATCCTTTTCTATCTTGGATGATGTGTATCCT
TGGGATTTGAGCGAAATTTACAATCCGCCCGTTCTTCTTTTTTATAAAGGTAATTTGGATTTGCTAAAATTACCTAAAGT
AGCTGTTGTAGGAAGTCGGAATAGTAGCCGAGTAGGCAGTCAATCCGTTCAAAAGATTATTAAAGAGCTAAACAATGAAT
TGGTTATCGTGAGTGGTTTAGCACGCGGAATTGATACCTCGGCTCACATGGCAGCATTGCAAAATGGTGGTCGAACAATT
GCAGTTATCGGAACGGGTCTAGACGTTTTTTATCCAAGGGCGAATAAAAAACTCCAATCGTATTTGGGAGAACATCATCT
AGTACTTAGTGAATATGGTTCTGAAGCAGAGCCATTAAAATTTCATTTTCCAGAGCGTAATCGGATTATAGCAGGATTGT
GCAGAGGGGTTATTGTTGCTGAAGCCAAAATGCGCTCAGGCAGTTTAATTACTTGTGAGCGCGCGATGGAAGAAGGACGA
GATGTGTTTGCTATTCCAGGGTCAATTTTAGACGGCAGAAGTGATGGCTGTCATCATTTGATTCAAGAGGGTGCAAAGTG
TGTCACATCAGGCGCTGACGTACTTTCTGAATTCCAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(71-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

76.429

100

0.764
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae D39

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae R6

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

76.071

100

0.761
  dprA/cilB/dalA Streptococcus mitis SK321

75.714

100

0.757
  dprA Streptococcus mutans UA159

65

100

0.65
  dprA Lactococcus lactis subsp. cremoris KW2

57.857

100

0.579
  dprA Staphylococcus aureus N315

37.943

100

0.382
  dprA Legionella pneumophila strain ERS1305867

44.398

86.071

0.382
  dprA Staphylococcus aureus MW2

37.722

100

0.379
  dprA Bacillus subtilis subsp. subtilis str. 168

44.934

81.071

0.364