Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   PHA78_RS03625 Genome accession   NZ_CP116604
Coordinates   741307..741969 (+) Length   220 a.a.
NCBI ID   WP_099807221.1    Uniprot ID   -
Organism   Streptococcus sp. HN38     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 736307..746969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA78_RS03605 - 737019..737948 (-) 930 WP_029178642.1 ABC transporter substrate-binding protein -
  PHA78_RS03610 - 737961..738746 (-) 786 WP_272158462.1 ABC transporter ATP-binding protein -
  PHA78_RS03615 - 738898..740343 (-) 1446 WP_272158463.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  PHA78_RS03620 - 740491..741237 (+) 747 WP_014735985.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  PHA78_RS03625 comEA/celA/cilE 741307..741969 (+) 663 WP_099807221.1 helix-hairpin-helix domain-containing protein Machinery gene
  PHA78_RS03630 comEC/celB 741953..744190 (+) 2238 WP_099807220.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23431.03 Da        Isoelectric Point: 3.9754

>NTDB_id=778760 PHA78_RS03625 WP_099807221.1 741307..741969(+) (comEA/celA/cilE) [Streptococcus sp. HN38]
MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQLEQTSSSSELVEETSTEESEEPSQLVVDVK
GAVTEPGIYYLDAGSRVNDAVDAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSQEEKSTSLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=778760 PHA78_RS03625 WP_099807221.1 741307..741969(+) (comEA/celA/cilE) [Streptococcus sp. HN38]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCCGCAGTGGCTGGCTTGCT
AATGGCGACATTTTTAATCTTCAGTCAACCAGCCAAGTCTGACCAGACGGGTCTGACTGATTTTCCCCAGCTAGAGCAAA
CTTCTAGCAGCTCTGAGTTGGTCGAGGAAACCAGTACAGAAGAAAGCGAAGAGCCGAGCCAGCTGGTCGTCGATGTCAAA
GGAGCGGTGACGGAACCTGGCATTTACTACCTTGATGCAGGAAGTCGGGTCAATGATGCAGTTGATGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAAGCGGTGGTCTATGTGGCCAGCAAGG
ATGAAAATATCTCGGTGGTTGCCAGCACGACTGCCAGCTCTGCTATGTCCCAAGAAGAAAAAAGCACCAGTCTGGTCAAT
CTGAATACGGCGACTGAGGCTGACCTGCAGACCATTTCAGGTATTGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCCAATGGCGGCTTCAAGTCGGTGGACGACCTCAACAATGTATCGGGCATCGGCGACAAGACCATGGAAAGTATCC
GACCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(157-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

49.315

99.545

0.491
  comEA/celA/cilE Streptococcus pneumoniae Rx1

49.315

99.545

0.491
  comEA/celA/cilE Streptococcus pneumoniae D39

49.315

99.545

0.491
  comEA/celA/cilE Streptococcus pneumoniae R6

49.315

99.545

0.491
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

49.083

99.091

0.486
  comEA/celA/cilE Streptococcus mitis SK321

47.297

100

0.477
  comEA Streptococcus thermophilus LMD-9

58.025

73.636

0.427
  comEA Lactococcus lactis subsp. cremoris KW2

38.249

98.636

0.377