Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   PHA78_RS03630 Genome accession   NZ_CP116604
Coordinates   741953..744190 (+) Length   745 a.a.
NCBI ID   WP_099807220.1    Uniprot ID   -
Organism   Streptococcus sp. HN38     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 736953..749190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA78_RS03605 - 737019..737948 (-) 930 WP_029178642.1 ABC transporter substrate-binding protein -
  PHA78_RS03610 - 737961..738746 (-) 786 WP_272158462.1 ABC transporter ATP-binding protein -
  PHA78_RS03615 - 738898..740343 (-) 1446 WP_272158463.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  PHA78_RS03620 - 740491..741237 (+) 747 WP_014735985.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  PHA78_RS03625 comEA/celA/cilE 741307..741969 (+) 663 WP_099807221.1 helix-hairpin-helix domain-containing protein Machinery gene
  PHA78_RS03630 comEC/celB 741953..744190 (+) 2238 WP_099807220.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 84156.01 Da        Isoelectric Point: 7.0412

>NTDB_id=778761 PHA78_RS03630 WP_099807220.1 741953..744190(+) (comEC/celB) [Streptococcus sp. HN38]
MSRLSKLPCQPIHLAVLAVAAYFAVHSFSLLTMGLLSFLLVVFGFRQGKAVFLKTLPLLALCSLFFGCQKVQWERADQSA
PEQVTTVQIIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQAYFQKLTDLVQLEVEAEISLPAGQRNFNGFDYQAYL
KTQGIYRTVKLTAIKKISPVQSWNVFDWLSSLRRQALVYVKTNFPAPMSHYMTGLLFGELDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWMLLRLGLTKETVDKLQLPFSIVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPLVKITWVNGFFVFMEKIIVWVADLGFRPWILGKPSELVLLLLLVSLFMLYDFHRRKKWLLGLGLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRIDFAAKEEWQERSRQTNAERTLIPYLHSRGMDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIIVSPGSLTEPDFVATLKEINVPVHVVEVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
KTNFLFTGDLEQGELDLLKTYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQATLERFDNRNIQ
VYRTDQQGAIRFRGWREWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=778761 PHA78_RS03630 WP_099807220.1 741953..744190(+) (comEC/celB) [Streptococcus sp. HN38]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCATTCACCTGGCTGTCTTAGCGGTGGCGGCCTACTTTGCAGTCCACTC
TTTCTCCCTGTTGACAATGGGCCTGTTGAGTTTCTTACTAGTTGTCTTTGGGTTTCGGCAAGGTAAGGCAGTTTTTCTCA
AAACGCTGCCGCTTCTAGCCCTGTGTAGTTTGTTTTTCGGATGCCAGAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAGCAAGTGACGACTGTGCAGATTATTCCAGATACGATTGAAGTAAACGGGGACAGCTTGTCTTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTACAAATTAGCTAGTCAGGAGGAGCAGGCTTATTTTCAAAAGTTGACAGATTTGG
TCCAGCTAGAAGTGGAAGCAGAGATTAGCCTGCCAGCTGGTCAGCGGAATTTCAACGGTTTTGATTATCAGGCCTATCTG
AAAACCCAGGGCATCTATCGGACTGTCAAGCTAACGGCGATAAAAAAGATTTCCCCAGTCCAGTCTTGGAATGTCTTTGA
CTGGCTATCAAGCTTGCGGAGGCAAGCCCTGGTCTATGTCAAAACCAATTTTCCAGCTCCTATGAGTCACTACATGACAG
GGCTCTTGTTTGGGGAGTTGGATAGTGAGTTTGACCAGATGAGTGACCTCTATTCTAGTCTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGACAAGTTTCGCTGGATGTTGTTGCGTCTGGGCTTGACCAAGGAAAC
GGTGGATAAATTGCAGCTTCCCTTTTCCATTGTTTATGCTGGTTTGACAGGTTTTTCTGTGTCTGTGGTGCGGTCCTTGG
TCCAAAAAATTTTAGGCAATCTGGGCTTGCGGAAGCTGGATAACTTTGCGGTGACAGTCTTTGTCTGTCTGTTGATACTG
CCCCGATTTCTGCTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTTTTTTACTGACAGTCTTTGATTTTGAAGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCTTTGTCTATCCTCTTGACCTTTGTCTTTTCCTTTGTCTTTGATGTCCTGCTTTTGCCAGGATTGTCGGTC
ATTTTTCTTCTATCGCCCTTGGTTAAGATTACTTGGGTCAACGGATTTTTCGTCTTTATGGAAAAAATCATTGTCTGGGT
GGCTGATTTGGGTTTTCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTTTTGCTCTTGCTGGTCAGCCTATTCA
TGCTCTACGATTTTCACAGGAGGAAGAAATGGCTCTTAGGACTAGGGCTGGTCCTCGCTCTGCTATTTTTCATTACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTAGGCGGACGAATCGATTTCGCGGCCAAGGAAGAGTGGCAGGAGCGGTCTCGGCAGACAAATGCAG
AGCGGACCTTGATTCCCTATCTGCACAGTCGAGGTATGGATAGGATTGATAGTCTAGTGCTGACCCACACAGACACAGAT
CATGTGGGCGATGTGCTGGAAGTGGCCAAGCAGGTCCAGATTGGTCGGATTATCGTGTCGCCGGGAAGTCTGACTGAGCC
TGACTTTGTAGCAACTCTGAAAGAAATCAATGTACCTGTTCATGTGGTGGAGGTGGGCGACCGATTGCCGATTTTTGACT
CTTACCTGGAAGTCCTTTATCCAGATGGGACAGGAGACGGTGGGAATAATGATTCCATCGTTCTTTATGGCCGCTTGCTG
AAAACTAATTTTCTTTTTACTGGGGACTTGGAGCAGGGGGAGTTGGACTTGCTTAAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAGGCTGGGCACCATGGCTCAAAAGGTTCTTCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCTC
TGGTATCAGCAGGAGAAAACAATCGTTACAAACACCCCCACCAAGCAACCTTGGAACGATTTGACAATCGGAATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGGAATGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Competence protein (Competence)

(215-461)

Domain of unknown function (DUF4131) (DUF4131)

(28-175)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.398

99.195

0.54
  comEC/celB Streptococcus mitis NCTC 12261

53.406

98.523

0.526
  comEC/celB Streptococcus pneumoniae TIGR4

52.517

98.658

0.518
  comEC/celB Streptococcus pneumoniae Rx1

52.381

98.658

0.517
  comEC/celB Streptococcus pneumoniae D39

52.381

98.658

0.517
  comEC/celB Streptococcus pneumoniae R6

52.381

98.658

0.517
  comEC Lactococcus lactis subsp. cremoris KW2

48.8

100

0.491