Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PML91_RS12230 Genome accession   NZ_CP116569
Coordinates   2570694..2571938 (-) Length   414 a.a.
NCBI ID   WP_002424926.1    Uniprot ID   -
Organism   Enterococcus faecalis strain K198-1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2565694..2576938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PML91_RS12205 (PML91_12205) - 2566008..2567471 (-) 1464 WP_002407853.1 glycoside hydrolase family 1 protein -
  PML91_RS12210 (PML91_12210) - 2567453..2567794 (-) 342 WP_002359005.1 PTS lactose/cellobiose transporter subunit IIA -
  PML91_RS12215 (PML91_12215) - 2567814..2569064 (-) 1251 WP_081115783.1 PTS sugar transporter subunit IIC -
  PML91_RS12220 (PML91_12220) - 2569069..2569374 (-) 306 WP_010821936.1 hypothetical protein -
  PML91_RS12225 (PML91_12225) recA 2569534..2570580 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  PML91_RS12230 (PML91_12230) cinA 2570694..2571938 (-) 1245 WP_002424926.1 competence/damage-inducible protein A Machinery gene
  PML91_RS12235 (PML91_12235) - 2572130..2573329 (+) 1200 WP_073438193.1 hypothetical protein -
  PML91_RS12240 (PML91_12240) - 2573409..2574038 (-) 630 WP_002365397.1 NAD(P)-dependent oxidoreductase -
  PML91_RS12245 (PML91_12245) - 2574097..2574522 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  PML91_RS12250 (PML91_12250) - 2574611..2574994 (-) 384 WP_002365398.1 YccF domain-containing protein -
  PML91_RS12255 (PML91_12255) - 2575158..2575949 (+) 792 WP_002354848.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45183.25 Da        Isoelectric Point: 4.6698

>NTDB_id=778450 PML91_RS12230 WP_002424926.1 2570694..2571938(-) (cinA) [Enterococcus faecalis strain K198-1]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDSIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=778450 PML91_RS12230 WP_002424926.1 2570694..2571938(-) (cinA) [Enterococcus faecalis strain K198-1]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTACACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGGACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTT
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCGAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCCCAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGCGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACTCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.632

100

0.531
  cinA Streptococcus mitis SK321

51.773

100

0.529
  cinA Streptococcus mitis NCTC 12261

51.537

100

0.527
  cinA Streptococcus pneumoniae TIGR4

50.827

100

0.519
  cinA Streptococcus pneumoniae D39

50.591

100

0.517
  cinA Streptococcus pneumoniae R6

50.355

100

0.514
  cinA Streptococcus pneumoniae Rx1

50.355

100

0.514
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.282

99.275

0.44