Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PML79_RS12680 Genome accession   NZ_CP116566
Coordinates   2616917..2618161 (-) Length   414 a.a.
NCBI ID   WP_010710870.1    Uniprot ID   -
Organism   Enterococcus faecalis strain K191-1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2611917..2623161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PML79_RS12660 (PML79_12660) - 2612387..2612773 (-) 387 WP_025188759.1 RicAFT regulatory complex protein RicA family protein -
  PML79_RS12665 (PML79_12665) - 2612847..2613644 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  PML79_RS12670 (PML79_12670) rny 2613804..2615360 (-) 1557 WP_002354863.1 ribonuclease Y -
  PML79_RS12675 (PML79_12675) recA 2615757..2616803 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  PML79_RS12680 (PML79_12680) cinA 2616917..2618161 (-) 1245 WP_010710870.1 competence/damage-inducible protein A Machinery gene
  PML79_RS12685 (PML79_12685) - 2618353..2619558 (+) 1206 WP_002367468.1 hypothetical protein -
  PML79_RS12690 (PML79_12690) - 2619637..2620266 (-) 630 WP_161975128.1 NAD(P)-dependent oxidoreductase -
  PML79_RS12695 (PML79_12695) - 2620422..2620898 (-) 477 WP_002408372.1 Rrf2 family transcriptional regulator -
  PML79_RS12700 (PML79_12700) - 2620987..2621370 (-) 384 WP_002358999.1 YccF domain-containing protein -
  PML79_RS12705 (PML79_12705) - 2621534..2622325 (+) 792 WP_010713701.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45193.29 Da        Isoelectric Point: 4.6698

>NTDB_id=778414 PML79_RS12680 WP_010710870.1 2616917..2618161(-) (cinA) [Enterococcus faecalis strain K191-1]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=778414 PML79_RS12680 WP_010710870.1 2616917..2618161(-) (cinA) [Enterococcus faecalis strain K191-1]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCTTATGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGGACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.537

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.3

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.591

100

0.517
  cinA Streptococcus pneumoniae D39

50.355

100

0.514
  cinA Streptococcus pneumoniae R6

50.118

100

0.512
  cinA Streptococcus pneumoniae Rx1

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437