Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PML77_RS11990 Genome accession   NZ_CP116528
Coordinates   2460305..2461546 (-) Length   413 a.a.
NCBI ID   WP_002337397.1    Uniprot ID   A0A3F3M3F5
Organism   Enterococcus faecium strain K188-5     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2455305..2466546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PML77_RS11975 (PML77_11975) proC 2456295..2457101 (+) 807 WP_002296027.1 pyrroline-5-carboxylate reductase -
  PML77_RS11980 (PML77_11980) rny 2457180..2458736 (-) 1557 WP_002287336.1 ribonuclease Y -
  PML77_RS11985 (PML77_11985) recA 2459147..2460196 (-) 1050 WP_002307721.1 recombinase RecA Machinery gene
  PML77_RS11990 (PML77_11990) cinA 2460305..2461546 (-) 1242 WP_002337397.1 competence/damage-inducible protein A Machinery gene
  PML77_RS11995 (PML77_11995) pgsA 2461786..2462364 (-) 579 WP_231428653.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PML77_RS12000 (PML77_12000) - 2462573..2463496 (-) 924 WP_002287423.1 RodZ domain-containing protein -
  PML77_RS12005 (PML77_12005) yfmH 2463987..2465273 (-) 1287 WP_002287425.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  PML77_RS12010 (PML77_12010) yfmF 2465266..2466534 (-) 1269 WP_002287428.1 EF-P 5-aminopentanol modification-associated protein YfmF -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45429.79 Da        Isoelectric Point: 4.6507

>NTDB_id=777936 PML77_RS11990 WP_002337397.1 2460305..2461546(-) (cinA) [Enterococcus faecium strain K188-5]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGIPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTNDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=777936 PML77_RS11990 WP_002337397.1 2460305..2461546(-) (cinA) [Enterococcus faecium strain K188-5]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATTATCGAAGGCGGGATTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGAGACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGATGTTCAAGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATGATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGCGCCTTCCAAGCCGCATTGGGCGATATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTGGTTTCGGAAAAATATCACTTTGCCAGAGATCGTGCTGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3F3M3F5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.19

100

0.521
  cinA Streptococcus pneumoniae TIGR4

51.19

100

0.521
  cinA Streptococcus mutans UA159

51.566

100

0.518
  cinA Streptococcus pneumoniae D39

50.952

100

0.518
  cinA Streptococcus pneumoniae R6

50.952

100

0.518
  cinA Streptococcus pneumoniae Rx1

50.952

100

0.518
  cinA Streptococcus mitis NCTC 12261

50.952

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

47.573

99.758

0.475
  cinA Streptococcus suis isolate S10

41.787

100

0.419