Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PML82_RS11900 Genome accession   NZ_CP116514
Coordinates   2444222..2445463 (-) Length   413 a.a.
NCBI ID   WP_002325519.1    Uniprot ID   A0A9X3XUY5
Organism   Enterococcus faecium strain K195-6b     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2439222..2450463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PML82_RS11885 (PML82_11885) proC 2440212..2441018 (+) 807 WP_272019577.1 pyrroline-5-carboxylate reductase -
  PML82_RS11890 (PML82_11890) rny 2441097..2442653 (-) 1557 WP_002287336.1 ribonuclease Y -
  PML82_RS11895 (PML82_11895) recA 2443064..2444113 (-) 1050 WP_002287328.1 recombinase RecA Machinery gene
  PML82_RS11900 (PML82_11900) cinA 2444222..2445463 (-) 1242 WP_002325519.1 competence/damage-inducible protein A Machinery gene
  PML82_RS11905 (PML82_11905) pgsA 2445703..2446281 (-) 579 WP_002298210.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PML82_RS11910 (PML82_11910) - 2446490..2447413 (-) 924 WP_002287423.1 RodZ domain-containing protein -
  PML82_RS11915 (PML82_11915) yfmH 2448149..2449435 (-) 1287 WP_002287425.1 EF-P 5-aminopentanol modification-associated protein YfmH -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45385.74 Da        Isoelectric Point: 4.6473

>NTDB_id=777788 PML82_RS11900 WP_002325519.1 2444222..2445463(-) (cinA) [Enterococcus faecium strain K195-6b]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIDTQINPTIAPYAKPNEVTLRLTVKTNDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRFNAVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=777788 PML82_RS11900 WP_002325519.1 2444222..2445463(-) (cinA) [Enterococcus faecium strain K195-6b]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATTATCGAAGGCGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTAAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGATACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGATGTTCAGGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATGATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGCGCCTTCCAAGCCGCATTAGGCGACATTG
CTGGTGTGTCTGAAGTATTTCCAGGCGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTGGTTTCGGAAAAATATCACTTTGCCAGAGATCGTGCTGCTATCAGATTTAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.429

100

0.523
  cinA Streptococcus pneumoniae TIGR4

51.19

100

0.521
  cinA Streptococcus pneumoniae R6

50.952

100

0.518
  cinA Streptococcus pneumoniae Rx1

50.952

100

0.518
  cinA Streptococcus mitis NCTC 12261

50.952

100

0.518
  cinA Streptococcus pneumoniae D39

50.952

100

0.518
  cinA Streptococcus mutans UA159

51.325

100

0.516
  cinA Bacillus subtilis subsp. subtilis str. 168

47.816

99.758

0.477
  cinA Streptococcus suis isolate S10

42.029

100

0.421