Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PE069_RS08775 Genome accession   NZ_CP115992
Coordinates   1831535..1832779 (-) Length   414 a.a.
NCBI ID   WP_333781551.1    Uniprot ID   -
Organism   Enterococcus faecalis strain ESC1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1826535..1837779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PE069_RS08755 (PE069_08755) - 1827005..1827391 (-) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -
  PE069_RS08760 (PE069_08760) - 1827465..1828262 (-) 798 WP_271232305.1 TIGR00282 family metallophosphoesterase -
  PE069_RS08765 (PE069_08765) rny 1828422..1829978 (-) 1557 WP_002354863.1 ribonuclease Y -
  PE069_RS08770 (PE069_08770) recA 1830375..1831421 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  PE069_RS08775 (PE069_08775) cinA 1831535..1832779 (-) 1245 WP_333781551.1 competence/damage-inducible protein A Machinery gene
  PE069_RS08780 (PE069_08780) - 1832971..1834176 (+) 1206 WP_002360981.1 hypothetical protein -
  PE069_RS08785 (PE069_08785) - 1834256..1834885 (-) 630 WP_175404156.1 NAD(P)-dependent oxidoreductase -
  PE069_RS08790 (PE069_08790) - 1834944..1835369 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  PE069_RS08795 (PE069_08795) - 1835458..1835841 (-) 384 WP_002358999.1 YccF domain-containing protein -
  PE069_RS08800 (PE069_08800) - 1836005..1836796 (+) 792 WP_271232307.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45283.43 Da        Isoelectric Point: 4.6698

>NTDB_id=774790 PE069_RS08775 WP_333781551.1 1831535..1832779(-) (cinA) [Enterococcus faecalis strain ESC1]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDSFPQEEQLISRVLRFYGIGESQLVTEIQSLIVHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNRQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKACQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=774790 PE069_RS08775 WP_333781551.1 1831535..1832779(-) (cinA) [Enterococcus faecalis strain ESC1]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAATTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAGCATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGACCACCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATTCGTTTCCACAAGAAGAGCAATTGATTTCAAGAGTCTTGCGTTTTTATGG
GATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGTGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACAGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CTGGCGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGTGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGGGGGTTAGATCTTTTACGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.675

100

0.522
  cinA Streptococcus mitis SK321

51.064

100

0.522
  cinA Streptococcus mitis NCTC 12261

50.827

100

0.519
  cinA Streptococcus pneumoniae TIGR4

50.118

100

0.512
  cinA Streptococcus pneumoniae D39

49.882

100

0.51
  cinA Streptococcus pneumoniae Rx1

49.645

100

0.507
  cinA Streptococcus pneumoniae R6

49.645

100

0.507
  cinA Bacillus subtilis subsp. subtilis str. 168

48.276

98.068

0.473
  cinA Streptococcus suis isolate S10

44.31

99.758

0.442