Detailed information NTG0761451

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: OS912_RS10790
• Genome accession: NZ_CP113266
• Coordinates: 2114735..2115385 (+)
• Length: 216 a.a.
• NCBI ID: WP_001866227.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain BC1
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2109735..2120385

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OS912_RS10760 (OS912_10765)	pyrH	2110459..2111196 (+)	738	WP_000002997.1	UMP kinase	-
OS912_RS10765 (OS912_10770)	frr	2111205..2111762 (+)	558	WP_000024409.1	ribosome recycling factor	-
OS912_RS10770 (OS912_10775)	cvfB	2111822..2112676 (+)	855	WP_044791153.1	RNA-binding virulence regulatory protein CvfB	-
OS912_RS10775 (OS912_10780)	-	2112685..2112900 (+)	216	WP_001232085.1	YozE family protein	-
OS912_RS10780 (OS912_10785)	-	2112986..2113990 (+)	1005	WP_050096410.1	PhoH family protein	-
OS912_RS10785 (OS912_10790)	-	2114098..2114667 (+)	570	WP_050227512.1	GNAT family N-acetyltransferase	-
OS912_RS10790 (OS912_10795)	comEA/celA/cilE	2114735..2115385 (+)	651	WP_001866227.1	helix-hairpin-helix domain-containing protein	Machinery gene
OS912_RS10795 (OS912_10800)	comEC/celB	2115369..2117609 (+)	2241	WP_050227511.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
OS912_RS10800 (OS912_10805)	-	2117788..2117976 (+)	189	WP_001809102.1	hypothetical protein	-
OS912_RS10805 (OS912_10810)	-	2118008..2118595 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
OS912_RS10810 (OS912_10815)	-	2118599..2119780 (+)	1182	WP_000655951.1	membrane protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23095.34 Da
• Isoelectric Point: 6.0661

>NTDB_id=761451 OS912_RS10790 WP_001866227.1 2114735..2115385(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain BC1]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=761451 OS912_RS10790 WP_001866227.1 2114735..2115385(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain BC1]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGACT
CATCGACCGGAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATTGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGCCAAGACCATAGAAAAACTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae Rx1	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae D39	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae R6	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	93.056	100	0.931
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Latilactobacillus sakei subsp. sakei 23K	34.335	100	0.37
comEA	Bacillus subtilis subsp. subtilis str. 168	41.053	87.963	0.361