Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   OS912_RS10795 Genome accession   NZ_CP113266
Coordinates   2115369..2117609 (+) Length   746 a.a.
NCBI ID   WP_050227511.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2110369..2122609
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS10760 (OS912_10765) pyrH 2110459..2111196 (+) 738 WP_000002997.1 UMP kinase -
  OS912_RS10765 (OS912_10770) frr 2111205..2111762 (+) 558 WP_000024409.1 ribosome recycling factor -
  OS912_RS10770 (OS912_10775) cvfB 2111822..2112676 (+) 855 WP_044791153.1 RNA-binding virulence regulatory protein CvfB -
  OS912_RS10775 (OS912_10780) - 2112685..2112900 (+) 216 WP_001232085.1 YozE family protein -
  OS912_RS10780 (OS912_10785) - 2112986..2113990 (+) 1005 WP_050096410.1 PhoH family protein -
  OS912_RS10785 (OS912_10790) - 2114098..2114667 (+) 570 WP_050227512.1 GNAT family N-acetyltransferase -
  OS912_RS10790 (OS912_10795) comEA/celA/cilE 2114735..2115385 (+) 651 WP_001866227.1 helix-hairpin-helix domain-containing protein Machinery gene
  OS912_RS10795 (OS912_10800) comEC/celB 2115369..2117609 (+) 2241 WP_050227511.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  OS912_RS10800 (OS912_10805) - 2117788..2117976 (+) 189 WP_001809102.1 hypothetical protein -
  OS912_RS10805 (OS912_10810) - 2118008..2118595 (+) 588 WP_000933542.1 ATP-binding cassette domain-containing protein -
  OS912_RS10810 (OS912_10815) - 2118599..2119780 (+) 1182 WP_000655951.1 membrane protein -
  OS912_RS10815 (OS912_10820) infC 2120087..2120617 (+) 531 WP_000848180.1 translation initiation factor IF-3 -
  OS912_RS10820 (OS912_10825) rpmI 2120650..2120850 (+) 201 WP_001125943.1 50S ribosomal protein L35 -
  OS912_RS10825 (OS912_10830) rplT 2120902..2121261 (+) 360 WP_000124836.1 50S ribosomal protein L20 -
  OS912_RS10830 (OS912_10835) - 2121319..2121699 (+) 381 WP_000157154.1 VOC family protein -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 84687.38 Da        Isoelectric Point: 9.5773

>NTDB_id=761452 OS912_RS10795 WP_050227511.1 2115369..2117609(+) (comEC/celB) [Streptococcus pneumoniae strain BC1]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCLFIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQN
LVDSVERVRILPDTIKVNGDSLSFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=761452 OS912_RS10795 WP_050227511.1 2115369..2117609(+) (comEC/celB) [Streptococcus pneumoniae strain BC1]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTGTTACTATGGCTTTACTACGCCATTTT
CTCAGTATCCTATTTTGCTTTGTTGGGTTTTGTTTTTCTGCTAGTCTGCCTCTTTATCCAATTTCCTTGGAAATCAGCAG
GTAAAGTTCTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAACTTGGCAACAGAGTCAAGTGAGTCAAAAT
TTGGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGACACTATTAAGGTCAACGGTGACAGTCTGTCCTTTCGTGGTAA
GTCTGATGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACTGACC
TTCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTGACTACCAAGGCTAT
CTGAAGACTCAGGGAATTTACCAGACACTCAATATTAAAAGAATCCAGTCACTCCAAAAGGTTGGTAGTTGGGATATAGG
TGAAAACCTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGATGCACTTCCCAGACCCTATGCGCAATTACATGA
CAGGACTTTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTAACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCAAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGGGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

Competence protein (Competence)

(216-458)

Domain of unknown function (DUF4131) (DUF4131)

(30-176)

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-693)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus pneumoniae Rx1

97.185

100

0.972
  comEC/celB Streptococcus pneumoniae D39

97.185

100

0.972
  comEC/celB Streptococcus pneumoniae R6

97.185

100

0.972
  comEC/celB Streptococcus pneumoniae TIGR4

96.783

100

0.968
  comEC/celB Streptococcus mitis SK321

91.555

100

0.916
  comEC/celB Streptococcus mitis NCTC 12261

91.409

99.866

0.913
  comEC Lactococcus lactis subsp. cremoris KW2

44.399

99.33

0.441