Detailed information NTG0760332

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: OTU45_RS04975
• Genome accession: NZ_CP113114
• Coordinates: 990229..990879 (+)
• Length: 216 a.a.
• NCBI ID: WP_001866227.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NP1
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 985229..995879

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OTU45_RS04945 (OTU45_04945)	-	985713..985928 (+)	216	WP_001232082.1	YozE family protein	-
OTU45_RS04950 (OTU45_04950)	-	986014..986982 (+)	969	WP_000658183.1	PhoH family protein	-
OTU45_RS04955 (OTU45_04955)	-	987175..987675 (+)	501	WP_050118047.1	GNAT family N-acetyltransferase	-
OTU45_RS04960 (OTU45_04960)	-	987678..988003 (+)	326	Protein_980	TfoX/Sxy family protein	-
OTU45_RS04965 (OTU45_04965)	ald	988304..989415 (-)	1112	Protein_981	alanine dehydrogenase	-
OTU45_RS04970 (OTU45_04970)	-	989592..990161 (+)	570	WP_000443739.1	GNAT family N-acetyltransferase	-
OTU45_RS04975 (OTU45_04975)	comEA/celA/cilE	990229..990879 (+)	651	WP_001866227.1	helix-hairpin-helix domain-containing protein	Machinery gene
OTU45_RS04980 (OTU45_04980)	comEC/celB	990863..993103 (+)	2241	WP_050118046.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
OTU45_RS04985 (OTU45_04985)	-	993245..993469 (+)	225	WP_050118045.1	hypothetical protein	-
OTU45_RS04990 (OTU45_04990)	-	993501..994088 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
OTU45_RS04995 (OTU45_04995)	-	994092..995273 (+)	1182	WP_050118044.1	hypothetical protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23095.34 Da
• Isoelectric Point: 6.0661

>NTDB_id=760332 OTU45_RS04975 WP_001866227.1 990229..990879(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain NP1]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=760332 OTU45_RS04975 WP_001866227.1 990229..990879(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain NP1]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGACT
CATCGACCGGAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATTGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGCCAAGACCATAGAAAAACTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae Rx1	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae D39	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae R6	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	93.056	100	0.931
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Latilactobacillus sakei subsp. sakei 23K	34.335	100	0.37
comEA	Bacillus subtilis subsp. subtilis str. 168	41.053	87.963	0.361