Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   UKS_RS01010 Genome accession   NZ_AP021887
Coordinates   197874..198176 (+) Length   100 a.a.
NCBI ID   WP_153197443.1    Uniprot ID   -
Organism   Streptococcus sp. 116-D4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 192874..203176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UKS_RS00980 (UKS_01760) - 193632..194690 (+) 1059 WP_000649461.1 zinc-dependent alcohol dehydrogenase family protein -
  UKS_RS00985 (UKS_01770) - 194842..195207 (+) 366 WP_156011419.1 DUF1033 family protein -
  UKS_RS00990 (UKS_01780) comGA/cglA/cilD 195284..196225 (+) 942 WP_156011420.1 competence type IV pilus ATPase ComGA Machinery gene
  UKS_RS00995 (UKS_01790) comGB/cglB 196173..197189 (+) 1017 WP_156013011.1 competence type IV pilus assembly protein ComGB Machinery gene
  UKS_RS01000 (UKS_01800) comGC/cglC 197191..197514 (+) 324 WP_049496909.1 comG operon protein ComGC Machinery gene
  UKS_RS01005 (UKS_01810) comGD/cglD 197477..197911 (+) 435 WP_049496906.1 competence type IV pilus minor pilin ComGD Machinery gene
  UKS_RS01010 (UKS_01820) comGE/cglE 197874..198176 (+) 303 WP_153197443.1 competence type IV pilus minor pilin ComGE Machinery gene
  UKS_RS01015 (UKS_01830) comGF/cglF 198139..198600 (+) 462 WP_049496903.1 competence type IV pilus minor pilin ComGF Machinery gene
  UKS_RS01020 (UKS_01840) comGG/cglG 198578..198991 (+) 414 WP_156011421.1 competence type IV pilus minor pilin ComGG Machinery gene
  UKS_RS01025 (UKS_01850) - 199024..199611 (+) 588 WP_156011422.1 class I SAM-dependent methyltransferase -
  UKS_RS01030 (UKS_01860) comYH 199673..200626 (+) 954 WP_156011423.1 class I SAM-dependent methyltransferase Machinery gene
  UKS_RS01035 (UKS_01870) - 200676..201866 (+) 1191 WP_156011424.1 acetate kinase -
  UKS_RS01040 (UKS_01880) rnpA 202015..202386 (+) 372 WP_117306632.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11149.18 Da        Isoelectric Point: 10.0522

>NTDB_id=75324 UKS_RS01010 WP_153197443.1 197874..198176(+) (comGE/cglE) [Streptococcus sp. 116-D4]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVKINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=75324 UKS_RS01010 WP_153197443.1 197874..198176(+) (comGE/cglE) [Streptococcus sp. 116-D4]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTTGCTCTAGCCATCTT
TGCCAGCATAGCAACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAAGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGCGTGTAGCTAAGATGGCTCTGCAGACAGGTCAAAATCAGGTAAAGATCAACGGAGTTGAGATTCAGGTGTTTTCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis SK321

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment