Detailed information NTG0075325

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: UKS_RS01015
• Genome accession: NZ_AP021887
• Coordinates: 198139..198600 (+)
• Length: 153 a.a.
• NCBI ID: WP_049496903.1
• Uniprot ID: -
• Organism: Streptococcus sp. 116-D4
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 193139..203600

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UKS_RS00980 (UKS_01760)	-	193632..194690 (+)	1059	WP_000649461.1	zinc-dependent alcohol dehydrogenase family protein	-
UKS_RS00985 (UKS_01770)	-	194842..195207 (+)	366	WP_156011419.1	DUF1033 family protein	-
UKS_RS00990 (UKS_01780)	comGA/cglA/cilD	195284..196225 (+)	942	WP_156011420.1	competence type IV pilus ATPase ComGA	Machinery gene
UKS_RS00995 (UKS_01790)	comGB/cglB	196173..197189 (+)	1017	WP_156013011.1	competence type IV pilus assembly protein ComGB	Machinery gene
UKS_RS01000 (UKS_01800)	comGC/cglC	197191..197514 (+)	324	WP_049496909.1	comG operon protein ComGC	Machinery gene
UKS_RS01005 (UKS_01810)	comGD/cglD	197477..197911 (+)	435	WP_049496906.1	competence type IV pilus minor pilin ComGD	Machinery gene
UKS_RS01010 (UKS_01820)	comGE/cglE	197874..198176 (+)	303	WP_153197443.1	competence type IV pilus minor pilin ComGE	Machinery gene
UKS_RS01015 (UKS_01830)	comGF/cglF	198139..198600 (+)	462	WP_049496903.1	competence type IV pilus minor pilin ComGF	Machinery gene
UKS_RS01020 (UKS_01840)	comGG/cglG	198578..198991 (+)	414	WP_156011421.1	competence type IV pilus minor pilin ComGG	Machinery gene
UKS_RS01025 (UKS_01850)	-	199024..199611 (+)	588	WP_156011422.1	class I SAM-dependent methyltransferase	-
UKS_RS01030 (UKS_01860)	comYH	199673..200626 (+)	954	WP_156011423.1	class I SAM-dependent methyltransferase	Machinery gene
UKS_RS01035 (UKS_01870)	-	200676..201866 (+)	1191	WP_156011424.1	acetate kinase	-
UKS_RS01040 (UKS_01880)	rnpA	202015..202386 (+)	372	WP_117306632.1	ribonuclease P protein component	-
UKS_RS01045 (UKS_01890)	-	202361..203185 (+)	825	WP_232049747.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17893.50 Da
• Isoelectric Point: 8.8053

>NTDB_id=75325 UKS_RS01015 WP_049496903.1 198139..198600(+) (comGF/cglF) [Streptococcus sp. 116-D4]
MVQNSCWQSKSHKVKAFTLLESLIALIVISGSLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYLKQDGKEIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEENQLIRFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=75325 UKS_RS01015 WP_049496903.1 198139..198600(+) (comGF/cglF) [Streptococcus sp. 116-D4]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTAAAGGCTTTCACTTTGTTGGAATCCCTGATTGCCCTTAT
TGTCATCAGTGGAAGCTTACTCCTCTTTCAAGCCATGAGTCAGCTCCTTATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAAGAGTGGCTCTTGTTTGTAGATCAGCTGGAGGCAGAATTAGATCGTTCGCAATTCGAAAAAGTGGAAGGTAAT
CGCCTCTATCTGAAGCAGGATGGCAAGGAAATTGCGATAGGTAAGTCCAAGTCAGATGATTTTCGGAAAACCGATGCCAG
TGGACGAGGCTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGAGAATCAGCTAATTCGTTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATTTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae Rx1	92.157	100	0.922
comGF/cglF	Streptococcus pneumoniae D39	92.157	100	0.922
comGF/cglF	Streptococcus pneumoniae R6	92.157	100	0.922
comGF/cglF	Streptococcus pneumoniae TIGR4	92.157	100	0.922
comGF	Lactococcus lactis subsp. cremoris KW2	41.429	91.503	0.379