Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   UKS_RS01030 Genome accession   NZ_AP021887
Coordinates   199673..200626 (+) Length   317 a.a.
NCBI ID   WP_156011423.1    Uniprot ID   A0A6H3SIK1
Organism   Streptococcus sp. 116-D4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 194673..205626
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UKS_RS00985 (UKS_01770) - 194842..195207 (+) 366 WP_156011419.1 DUF1033 family protein -
  UKS_RS00990 (UKS_01780) comGA/cglA/cilD 195284..196225 (+) 942 WP_156011420.1 competence type IV pilus ATPase ComGA Machinery gene
  UKS_RS00995 (UKS_01790) comGB/cglB 196173..197189 (+) 1017 WP_156013011.1 competence type IV pilus assembly protein ComGB Machinery gene
  UKS_RS01000 (UKS_01800) comGC/cglC 197191..197514 (+) 324 WP_049496909.1 comG operon protein ComGC Machinery gene
  UKS_RS01005 (UKS_01810) comGD/cglD 197477..197911 (+) 435 WP_049496906.1 competence type IV pilus minor pilin ComGD Machinery gene
  UKS_RS01010 (UKS_01820) comGE/cglE 197874..198176 (+) 303 WP_153197443.1 competence type IV pilus minor pilin ComGE Machinery gene
  UKS_RS01015 (UKS_01830) comGF/cglF 198139..198600 (+) 462 WP_049496903.1 competence type IV pilus minor pilin ComGF Machinery gene
  UKS_RS01020 (UKS_01840) comGG/cglG 198578..198991 (+) 414 WP_156011421.1 competence type IV pilus minor pilin ComGG Machinery gene
  UKS_RS01025 (UKS_01850) - 199024..199611 (+) 588 WP_156011422.1 class I SAM-dependent methyltransferase -
  UKS_RS01030 (UKS_01860) comYH 199673..200626 (+) 954 WP_156011423.1 class I SAM-dependent methyltransferase Machinery gene
  UKS_RS01035 (UKS_01870) - 200676..201866 (+) 1191 WP_156011424.1 acetate kinase -
  UKS_RS01040 (UKS_01880) rnpA 202015..202386 (+) 372 WP_117306632.1 ribonuclease P protein component -
  UKS_RS01045 (UKS_01890) - 202361..203185 (+) 825 WP_232049747.1 membrane protein insertase YidC -
  UKS_RS01050 (UKS_01900) jag 203203..204189 (+) 987 WP_156011426.1 RNA-binding cell elongation regulator Jag/EloR -
  UKS_RS01055 (UKS_01910) - 204240..204863 (+) 624 WP_156011427.1 ribonuclease P -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35745.92 Da        Isoelectric Point: 4.2706

>NTDB_id=75327 UKS_RS01030 WP_156011423.1 199673..200626(+) (comYH) [Streptococcus sp. 116-D4]
MDFEKIEQAYTYLLENVQVIQSDLTTNFYDALVEQNSIYLDGETELKQVKENNQALKRLALRREEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDTIASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKGWLKEEASLIAMISLPENLFASANQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=75327 UKS_RS01030 WP_156011423.1 199673..200626(+) (comYH) [Streptococcus sp. 116-D4]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATTCAAAGTGACTTGACGACCAA
CTTTTATGACGCCCTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAGACGGAGCTAAAACAGGTCAAAGAGAACAATC
AAGCCCTTAAGCGTTTAGCACTTCGCAGAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAGACA
GAGCCCCTACAGGCCAATCACCAGTTTACGCCAGATGCTATTGCTTTACTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAAGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCACTTGATAAAA
AGGTGGATTATTTGGGAATGGAAGTGGATGATTTGCTGATTGATTTGGCAGCTAGTATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAGATGCTCAAAGAAAGCGATGTGGTCATCAGCGACTTGCCTGTTGG
CTATTATCCTGATGATACCATTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCGCATCACTTGCTCA
TGGAACAAGGACTTAAGTATCTCAAGTCAGATGGATACGCTATTTTTCTCGCTCCTAGTGATTTGTTGACCAGTCCTCAG
AGTGATTTGTTGAAAGGGTGGTTGAAAGAGGAAGCGAGTCTGATTGCCATGATTAGTTTACCTGAAAATCTCTTTGCCAG
TGCTAACCAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCGAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6H3SIK1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.952

98.738

0.543
  comYH Streptococcus mutans UA159

54.633

98.738

0.539

Multiple sequence alignment