Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   OLM03_RS12745 Genome accession   NZ_CP110039
Coordinates   2600009..2601253 (-) Length   414 a.a.
NCBI ID   WP_002372760.1    Uniprot ID   -
Organism   Enterococcus faecalis strain BE47     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2595009..2606253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OLM03_RS12725 (OLM03_12725) - 2595479..2595865 (-) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -
  OLM03_RS12730 (OLM03_12730) - 2595939..2596736 (-) 798 WP_016630768.1 TIGR00282 family metallophosphoesterase -
  OLM03_RS12735 (OLM03_12735) rny 2596896..2598452 (-) 1557 WP_264547451.1 ribonuclease Y -
  OLM03_RS12740 (OLM03_12740) recA 2598849..2599895 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  OLM03_RS12745 (OLM03_12745) cinA 2600009..2601253 (-) 1245 WP_002372760.1 competence/damage-inducible protein A Machinery gene
  OLM03_RS12750 (OLM03_12750) - 2601445..2602650 (+) 1206 WP_016630766.1 hypothetical protein -
  OLM03_RS12755 (OLM03_12755) - 2602729..2603358 (-) 630 WP_002354854.1 NAD(P)-dependent oxidoreductase -
  OLM03_RS12760 (OLM03_12760) - 2603417..2603842 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  OLM03_RS12765 (OLM03_12765) - 2603931..2604314 (-) 384 WP_002358999.1 YccF domain-containing protein -
  OLM03_RS12770 (OLM03_12770) - 2604478..2605269 (+) 792 WP_202256356.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45173.26 Da        Isoelectric Point: 4.6629

>NTDB_id=751650 OLM03_RS12745 WP_002372760.1 2600009..2601253(-) (cinA) [Enterococcus faecalis strain BE47]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLINAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIASYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFQFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=751650 OLM03_RS12745 WP_002372760.1 2600009..2601253(-) (cinA) [Enterococcus faecalis strain BE47]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCTATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTT
CAACAAGCGGCACGACCTTTATTGATTAATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCACATCAAACGAATCCAACCATTGCGTCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCCGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTTACGGCTGCTGAGAGCCTCACTGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCAATTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.153

100

0.527
  cinA Streptococcus mitis SK321

51.3

100

0.524
  cinA Streptococcus mitis NCTC 12261

51.064

100

0.522
  cinA Streptococcus pneumoniae TIGR4

50.355

100

0.514
  cinA Streptococcus pneumoniae D39

50.118

100

0.512
  cinA Streptococcus pneumoniae Rx1

49.882

100

0.51
  cinA Streptococcus pneumoniae R6

49.882

100

0.51
  cinA Bacillus subtilis subsp. subtilis str. 168

48.03

98.068

0.471
  cinA Streptococcus suis isolate S10

43.796

99.275

0.435