Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   OGM83_RS12745 Genome accession   NZ_CP109611
Coordinates   2620210..2621454 (-) Length   414 a.a.
NCBI ID   WP_333781551.1    Uniprot ID   -
Organism   Enterococcus faecalis strain AFL-109F     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2615210..2626454
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OGM83_RS12725 (OGM83_12725) - 2615680..2616066 (-) 387 WP_002359008.1 YlbF family regulator -
  OGM83_RS12730 (OGM83_12730) - 2616140..2616937 (-) 798 WP_271232305.1 TIGR00282 family metallophosphoesterase -
  OGM83_RS12735 (OGM83_12735) rny 2617097..2618653 (-) 1557 WP_002354863.1 ribonuclease Y -
  OGM83_RS12740 (OGM83_12740) recA 2619050..2620096 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  OGM83_RS12745 (OGM83_12745) cinA 2620210..2621454 (-) 1245 WP_333781551.1 competence/damage-inducible protein A Machinery gene
  OGM83_RS12750 (OGM83_12750) - 2621646..2622851 (+) 1206 WP_002360981.1 hypothetical protein -
  OGM83_RS12755 (OGM83_12755) - 2622931..2623560 (-) 630 WP_175404156.1 NAD(P)-dependent oxidoreductase -
  OGM83_RS12760 (OGM83_12760) - 2623619..2624044 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  OGM83_RS12765 (OGM83_12765) - 2624133..2624516 (-) 384 WP_002358999.1 YccF domain-containing protein -
  OGM83_RS12770 (OGM83_12770) - 2624680..2625471 (+) 792 WP_271232307.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45283.43 Da        Isoelectric Point: 4.6698

>NTDB_id=748515 OGM83_RS12745 WP_333781551.1 2620210..2621454(-) (cinA) [Enterococcus faecalis strain AFL-109F]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDSFPQEEQLISRVLRFYGIGESQLVTEIQSLIVHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNRQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKACQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=748515 OGM83_RS12745 WP_333781551.1 2620210..2621454(-) (cinA) [Enterococcus faecalis strain AFL-109F]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAATTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAGCATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGACCACCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATTCGTTTCCACAAGAAGAGCAATTGATTTCAAGAGTCTTGCGTTTTTATGG
GATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGTGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACAGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CTGGCGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGTGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGGGGGTTAGATCTTTTACGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.675

100

0.522
  cinA Streptococcus mitis SK321

51.064

100

0.522
  cinA Streptococcus mitis NCTC 12261

50.827

100

0.519
  cinA Streptococcus pneumoniae TIGR4

50.118

100

0.512
  cinA Streptococcus pneumoniae D39

49.882

100

0.51
  cinA Streptococcus pneumoniae Rx1

49.645

100

0.507
  cinA Streptococcus pneumoniae R6

49.645

100

0.507
  cinA Bacillus subtilis subsp. subtilis str. 168

48.276

98.068

0.473
  cinA Streptococcus suis isolate S10

44.31

99.758

0.442