Detailed information NTG0737545

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: ODS73_RS04910
• Genome accession: NZ_CP107038
• Coordinates: 942907..943557 (+)
• Length: 216 a.a.
• NCBI ID: WP_284060646.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain BM6001
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 937907..948557

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ODS73_RS04880 (ODS73_04875)	-	938443..938658 (+)	216	WP_001232081.1	YozE family protein	-
ODS73_RS04885 (ODS73_04880)	-	938744..939712 (+)	969	WP_000658198.1	PhoH family protein	-
ODS73_RS04890 (ODS73_04885)	-	939905..940405 (+)	501	WP_000566986.1	GNAT family N-acetyltransferase	-
ODS73_RS04895 (ODS73_04890)	-	940408..940734 (+)	327	Protein_966	TfoX/Sxy family protein	-
ODS73_RS12200 (ODS73_04895)	ald	941035..942146 (-)	1112	Protein_967	alanine dehydrogenase	-
ODS73_RS04905 (ODS73_04900)	-	942323..942892 (+)	570	WP_000443774.1	GNAT family N-acetyltransferase	-
ODS73_RS04910 (ODS73_04905)	comEA/celA/cilE	942907..943557 (+)	651	WP_284060646.1	ComEA family DNA-binding protein	Machinery gene
ODS73_RS04915 (ODS73_04910)	comEC/celB	943541..945781 (+)	2241	WP_050087497.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ODS73_RS12075	-	945930..946147 (+)	218	Protein_971	hypothetical protein	-
ODS73_RS04920 (ODS73_04915)	-	946180..946767 (+)	588	WP_000939881.1	ATP-binding cassette domain-containing protein	-
ODS73_RS04925 (ODS73_04920)	-	946771..947955 (+)	1185	WP_016398520.1	hypothetical protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23298.72 Da
• Isoelectric Point: 6.0575

>NTDB_id=737545 ODS73_RS04910 WP_284060646.1 942907..943557(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain BM6001]
MFRLFFLPLEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=737545 ODS73_RS04910 WP_284060646.1 942907..943557(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain BM6001]
ATTTTTCGACTGTTTTTTCTTCCTCTAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	99.034	95.833	0.949
comEA/celA/cilE	Streptococcus pneumoniae D39	99.034	95.833	0.949
comEA/celA/cilE	Streptococcus pneumoniae R6	99.034	95.833	0.949
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.101	95.833	0.931
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.652	95.833	0.917
comEA/celA/cilE	Streptococcus mitis SK321	91.304	95.833	0.875
comEA	Lactococcus lactis subsp. cremoris KW2	43.119	100	0.435
comEA	Bacillus subtilis subsp. subtilis str. 168	38.318	99.074	0.38
comEA	Latilactobacillus sakei subsp. sakei 23K	34.322	100	0.375
comEA	Streptococcus thermophilus LMD-9	50	74.074	0.37