Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FNL60_RS09945 Genome accession   NZ_AP019720
Coordinates   1943353..1944609 (-) Length   418 a.a.
NCBI ID   WP_002280016.1    Uniprot ID   -
Organism   Streptococcus mutans strain NBRC 13955     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1938353..1949609
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNL60_RS09900 (SM3g_18280) - 1938545..1938844 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  FNL60_RS09905 (SM3g_18290) ruvX 1938925..1939344 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  FNL60_RS09910 (SM3g_18300) - 1939341..1939610 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  FNL60_RS09915 (SM3g_18310) brsR 1939778..1940212 (+) 435 WP_002280017.1 bacteriocin genes transcriptional regulator BrsR Regulator
  FNL60_RS09920 (SM3g_18320) brsM 1940225..1940671 (+) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  FNL60_RS09925 - 1940662..1940862 (-) 201 Protein_1852 hypothetical protein -
  FNL60_RS09930 (SM3g_18330) - 1941003..1941428 (-) 426 WP_002271571.1 hypothetical protein -
  FNL60_RS09935 (SM3g_18340) spx 1941679..1942077 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  FNL60_RS09940 (SM3g_18350) recA 1942162..1943313 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  FNL60_RS09945 (SM3g_18360) cinA 1943353..1944609 (-) 1257 WP_002280016.1 competence/damage-inducible protein A Machinery gene
  FNL60_RS09950 (SM3g_18370) - 1944758..1945318 (-) 561 WP_002266114.1 DNA-3-methyladenine glycosylase I -
  FNL60_RS09955 (SM3g_18380) ruvA 1945400..1945993 (-) 594 WP_002266975.1 Holliday junction branch migration protein RuvA -
  FNL60_RS09960 (SM3g_18390) mutL 1946175..1948130 (-) 1956 WP_002280015.1 DNA mismatch repair endonuclease MutL -
  FNL60_RS09965 - 1948356..1948634 (+) 279 Protein_1860 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45717.57 Da        Isoelectric Point: 6.7668

>NTDB_id=73560 FNL60_RS09945 WP_002280016.1 1943353..1944609(-) (cinA) [Streptococcus mutans strain NBRC 13955]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSKKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IVTIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAISLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=73560 FNL60_RS09945 WP_002280016.1 1943353..1944609(-) (cinA) [Streptococcus mutans strain NBRC 13955]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATTGTACTTTGCGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACACCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGCT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTAAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTGTAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTATTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Competence-damaged protein (CinA)

(259-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.522

100

0.995
  cinA Streptococcus mitis SK321

72.488

100

0.725
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.813

100

0.708
  cinA Streptococcus pneumoniae Rx1

70.574

100

0.706
  cinA Streptococcus pneumoniae R6

70.574

100

0.706
  cinA Streptococcus pneumoniae D39

70.335

100

0.703
  cinA Streptococcus suis isolate S10

55.474

98.325

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

46.005

98.804

0.455

Multiple sequence alignment