Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   N2A95_RS00480 Genome accession   NZ_CP104190
Coordinates   86785..88056 (+) Length   423 a.a.
NCBI ID   WP_003108931.1    Uniprot ID   -
Organism   Streptococcus parauberis strain HFTC0064     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 69366..97480 86785..88056 within 0


Gene organization within MGE regions


Location: 69366..97480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N2A95_RS00360 (N2A95_00360) - 69366..69980 (-) 615 WP_003107889.1 CadD family cadmium resistance transporter -
  N2A95_RS00365 (N2A95_00365) - 70640..71551 (+) 912 WP_003108896.1 hypothetical protein -
  N2A95_RS00370 (N2A95_00370) - 71747..72409 (+) 663 WP_003108897.1 hypothetical protein -
  N2A95_RS00375 (N2A95_00375) - 72570..73004 (-) 435 WP_003108899.1 DUF1492 domain-containing protein -
  N2A95_RS00380 (N2A95_00380) - 73010..73429 (-) 420 WP_003108900.1 DUF1492 domain-containing protein -
  N2A95_RS00385 (N2A95_00385) - 73443..73865 (-) 423 WP_003108901.1 hypothetical protein -
  N2A95_RS00390 (N2A95_00390) - 74040..74273 (-) 234 WP_003108902.1 hypothetical protein -
  N2A95_RS00395 (N2A95_00395) - 74288..74638 (-) 351 WP_003108903.1 hypothetical protein -
  N2A95_RS00400 (N2A95_00400) - 74640..75215 (-) 576 WP_003108905.1 hypothetical protein -
  N2A95_RS00405 (N2A95_00405) - 75369..75560 (-) 192 WP_146264510.1 hypothetical protein -
  N2A95_RS00410 (N2A95_00410) - 75569..75760 (-) 192 WP_003108907.1 hypothetical protein -
  N2A95_RS00415 (N2A95_00415) - 75750..76064 (-) 315 WP_003108909.1 hypothetical protein -
  N2A95_RS00420 (N2A95_00420) - 76347..77906 (-) 1560 WP_003108911.1 hypothetical protein -
  N2A95_RS00425 (N2A95_00425) - 78049..78573 (-) 525 WP_003108914.1 hypothetical protein -
  N2A95_RS00430 (N2A95_00430) - 78577..78849 (-) 273 WP_003108915.1 AlpA family transcriptional regulator -
  N2A95_RS00435 (N2A95_00435) - 78862..79095 (-) 234 WP_003108917.1 hypothetical protein -
  N2A95_RS00440 (N2A95_00440) - 79083..79307 (-) 225 WP_003108919.1 hypothetical protein -
  N2A95_RS00445 (N2A95_00445) - 79567..79773 (-) 207 WP_003108921.1 helix-turn-helix transcriptional regulator -
  N2A95_RS11160 - 79891..80724 (+) 834 WP_003108923.1 helix-turn-helix domain-containing protein -
  N2A95_RS00455 (N2A95_00455) - 80794..81939 (+) 1146 WP_003108925.1 site-specific integrase -
  N2A95_RS00460 (N2A95_00460) mutL 82036..84012 (+) 1977 WP_003108928.1 DNA mismatch repair endonuclease MutL -
  N2A95_RS00465 (N2A95_00465) - 84023..85246 (+) 1224 WP_003103803.1 MFS transporter -
  N2A95_RS00470 (N2A95_00470) ruvA 85248..85841 (+) 594 WP_003108930.1 Holliday junction branch migration protein RuvA -
  N2A95_RS00475 (N2A95_00475) - 85845..86396 (+) 552 WP_096633379.1 DNA-3-methyladenine glycosylase I -
  N2A95_RS00480 (N2A95_00480) cinA 86785..88056 (+) 1272 WP_003108931.1 competence/damage-inducible protein A Machinery gene
  N2A95_RS00485 (N2A95_00485) recA 88136..89275 (+) 1140 WP_003102546.1 recombinase RecA Machinery gene
  N2A95_RS00490 (N2A95_00490) spx 89629..90027 (+) 399 WP_003104943.1 transcriptional regulator Spx -
  N2A95_RS00495 (N2A95_00495) - 90141..90410 (+) 270 WP_003104158.1 IreB family regulatory phosphoprotein -
  N2A95_RS00500 (N2A95_00500) ruvX 90407..90826 (+) 420 WP_003105581.1 Holliday junction resolvase RuvX -
  N2A95_RS00505 (N2A95_00505) - 90837..91154 (+) 318 WP_003104776.1 DUF1292 domain-containing protein -
  N2A95_RS00510 (N2A95_00510) - 91303..92862 (+) 1560 WP_003108934.1 hypothetical protein -
  N2A95_RS00515 (N2A95_00515) nrdD 92962..95151 (+) 2190 WP_003102395.1 anaerobic ribonucleoside-triphosphate reductase -
  N2A95_RS00520 (N2A95_00520) - 95241..95390 (+) 150 WP_003108936.1 hypothetical protein -
  N2A95_RS00525 (N2A95_00525) - 95414..96376 (+) 963 WP_003108938.1 Gfo/Idh/MocA family protein -
  N2A95_RS00530 (N2A95_00530) - 96357..96851 (+) 495 WP_003108940.1 GNAT family N-acetyltransferase -
  N2A95_RS00535 (N2A95_00535) nrdG 96866..97480 (+) 615 WP_003104313.1 anaerobic ribonucleoside-triphosphate reductase activating protein -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46135.82 Da        Isoelectric Point: 4.8894

>NTDB_id=727914 N2A95_RS00480 WP_003108931.1 86785..88056(+) (cinA) [Streptococcus parauberis strain HFTC0064]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAEIGVDVYYHTAVGDNEIRLLNILEVASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGLSLVFDREASQKLDQFFSSRSESSRTPNNERQAQLIEGSKPIQNITGLAVGGLIEKAGVTYVVLPGPPSEMKPM
VNQYLLPLLLNEETKLYSRVLRFFGIGESQLVTILADLIANQLDPTIASYAKIGEVTLRLSTKSDSQELAYQKLDQLESQ
IKAISTIDGQLLGDLLYGYGEDNSLARETFQLLKKADKTITAAESLTAGLFQSKIADFPGSSSIFNGGFVTYSIEEKAKM
LEIPFADLQRKGVVSDYTAKQMANQARLLTESDIGVSLTGVAGPDFLEGQQAGTVFIGISTKEKVESYKVLIGGRSRSDV
RYIACLHAFNLVRKTLLNTQNLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=727914 N2A95_RS00480 WP_003108931.1 86785..88056(+) (cinA) [Streptococcus parauberis strain HFTC0064]
ATGAAAGCTGAATTAATTGCAGTCGGAACAGAAATCTTGACCGGTCAAATAGTTAATACGAACGCACAGTTTTTATCAGA
AAAAATGGCAGAGATTGGAGTTGATGTCTATTATCATACAGCAGTAGGCGATAATGAAATCAGATTATTAAATATCCTTG
AAGTTGCAAGTAAACGTAGTGATTTAGTGATATTATGTGGCGGTTTGGGACCTACTGAGGATGATTTGACTAAACAAACG
CTAGCTAAGTTTTTAGGTCTGTCATTGGTCTTTGACAGAGAAGCTAGTCAAAAACTGGACCAATTTTTTTCCTCTCGGTC
TGAGAGTTCTAGAACTCCAAATAATGAGAGGCAAGCACAGTTGATTGAAGGGTCCAAACCTATTCAAAACATTACAGGTC
TAGCTGTTGGTGGTTTAATCGAAAAAGCTGGTGTAACTTATGTCGTCTTACCTGGACCGCCTAGTGAAATGAAACCAATG
GTTAATCAGTATCTACTACCACTGTTGCTGAATGAGGAAACTAAACTCTACTCTCGTGTTTTACGTTTTTTTGGAATTGG
AGAAAGCCAATTAGTTACTATTTTAGCTGATCTTATTGCAAATCAATTAGACCCAACAATTGCTTCCTATGCCAAAATCG
GCGAGGTAACATTGCGCTTGTCAACTAAGTCTGATTCTCAAGAGCTAGCTTATCAAAAATTGGATCAATTAGAAAGTCAG
ATTAAGGCCATTTCAACTATAGATGGACAATTATTAGGAGACTTATTATATGGATATGGTGAGGATAATAGCCTGGCGCG
TGAGACTTTCCAGTTGTTAAAAAAAGCAGATAAGACAATTACAGCTGCAGAAAGTTTAACAGCAGGGCTATTCCAATCTA
AAATTGCTGATTTTCCAGGGTCATCCAGTATTTTTAACGGTGGATTTGTTACCTATAGTATCGAAGAAAAGGCAAAAATG
TTAGAGATTCCATTTGCTGATTTACAACGAAAAGGTGTTGTTAGTGATTATACTGCTAAACAAATGGCTAATCAAGCACG
ACTCTTAACTGAAAGTGATATTGGTGTTAGCTTAACTGGCGTTGCTGGTCCGGATTTCTTGGAAGGACAACAAGCAGGAA
CAGTTTTTATTGGTATTTCGACAAAAGAAAAAGTAGAATCATATAAGGTACTAATTGGCGGCAGGAGTCGCTCAGATGTC
AGATATATAGCTTGCTTACATGCCTTCAACCTAGTCCGAAAAACTTTATTAAATACCCAAAATTTGTTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-244)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

70.813

98.818

0.7
  cinA Streptococcus mutans UA159

69.74

100

0.697
  cinA Streptococcus mitis NCTC 12261

70.574

98.818

0.697
  cinA Streptococcus pneumoniae TIGR4

69.617

98.818

0.688
  cinA Streptococcus pneumoniae Rx1

69.378

98.818

0.686
  cinA Streptococcus pneumoniae R6

69.378

98.818

0.686
  cinA Streptococcus pneumoniae D39

69.139

98.818

0.683
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

46.172

98.818

0.456