Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   NX820_RS11585 Genome accession   NZ_CP103391
Coordinates   2316299..2317549 (-) Length   416 a.a.
NCBI ID   WP_011667974.1    Uniprot ID   M5AZ98
Organism   Levilactobacillus brevis strain PL102     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2311299..2322549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX820_RS11565 (NX820_11565) rny 2311503..2313062 (-) 1560 WP_011667971.1 ribonuclease Y -
  NX820_RS11570 (NX820_11570) - 2313390..2313542 (+) 153 WP_172757682.1 hypothetical protein -
  NX820_RS11575 (NX820_11575) - 2313694..2314956 (+) 1263 WP_035465312.1 ISL3 family transposase -
  NX820_RS11580 (NX820_11580) recA 2315072..2316205 (-) 1134 WP_043023201.1 recombinase RecA Machinery gene
  NX820_RS11585 (NX820_11585) cinA 2316299..2317549 (-) 1251 WP_011667974.1 competence/damage-inducible protein A Machinery gene
  NX820_RS11590 (NX820_11590) pgsA 2317605..2318192 (-) 588 WP_172757648.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NX820_RS11595 (NX820_11595) - 2318254..2319159 (-) 906 WP_011668110.1 helix-turn-helix domain-containing protein -
  NX820_RS11600 (NX820_11600) yfmH 2319273..2320562 (-) 1290 WP_011668111.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  NX820_RS11605 (NX820_11605) yfmF 2320540..2321835 (-) 1296 WP_011668112.1 EF-P 5-aminopentanol modification-associated protein YfmF -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 44778.88 Da        Isoelectric Point: 5.2849

>NTDB_id=722466 NX820_RS11585 WP_011667974.1 2316299..2317549(-) (cinA) [Levilactobacillus brevis strain PL102]
MQAEIIAVGTEILLGQIVDTNSAFIARELAEAGIEVYYHSLVGDNATRLTAVVEQARSRSDLVIISGGLGPTKDDLTKQT
VAHLLGVKLVEDALAMAKIRRRFAINGREMTPNNRLQALYPAGSQPLANRTGLAVGAFYQDPDGADIMLLPGPPSETEPM
FREQALPLLKQTYPRSEYLSSRVLRFFGIGESQLVTQLSDLIDQQTNPTIAPYAKVNEVTLRLTAQAPDEMQGQRLLDDL
TATIKARVGDYLYGYGDDNSLAAVVVQTLIDRQLTITAAESLTAGQFQSTLGSVPGVSAVFPGGFVTYAASAKHDLLGVS
QATIDQDGVVSAATAKEMASRSRERLDTDFSLSFTGVAGPDALEGQPAGTVWLGLAQRGQQPQAKLLHLTGTRSAIRERS
VLTGLDWLRRTLQKVK

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=722466 NX820_RS11585 WP_011667974.1 2316299..2317549(-) (cinA) [Levilactobacillus brevis strain PL102]
GTGCAAGCAGAAATTATTGCGGTTGGTACAGAGATTTTACTCGGGCAAATTGTGGATACGAACTCTGCCTTCATTGCGCG
CGAACTGGCGGAAGCTGGGATTGAGGTGTATTACCATTCTCTAGTAGGTGATAACGCAACCCGGTTAACGGCTGTTGTTG
AACAAGCCCGTTCGCGGAGCGATTTAGTGATTATTAGTGGGGGATTAGGACCGACCAAAGATGATTTGACAAAACAAACG
GTCGCTCACTTGTTAGGCGTAAAGTTGGTTGAAGATGCGTTGGCAATGGCTAAGATTCGTCGCCGGTTTGCTATCAATGG
CCGTGAGATGACGCCTAATAATCGCCTACAAGCTTTATATCCAGCAGGCAGTCAACCCTTAGCAAATCGGACGGGGTTAG
CTGTGGGAGCTTTTTATCAAGATCCTGATGGTGCGGACATCATGCTATTACCGGGACCACCAAGTGAGACTGAACCCATG
TTTCGTGAGCAAGCCTTACCCCTGCTGAAGCAAACATATCCACGAAGTGAGTACTTGTCTTCACGGGTACTTCGGTTCTT
TGGCATCGGCGAAAGTCAATTGGTCACTCAACTGAGTGATCTGATTGACCAGCAGACTAATCCGACCATCGCTCCTTATG
CTAAAGTTAATGAAGTAACGTTACGTTTAACCGCACAGGCCCCGGATGAGATGCAAGGGCAACGCCTCTTAGATGACTTA
ACGGCGACGATTAAGGCCCGCGTAGGGGATTATCTTTATGGTTATGGTGATGATAATTCATTGGCGGCAGTGGTGGTTCA
GACACTAATTGACCGTCAATTGACCATTACGGCTGCTGAGAGCTTAACGGCCGGTCAATTTCAAAGTACCTTGGGAAGTG
TTCCCGGTGTTTCGGCGGTTTTCCCTGGTGGTTTTGTCACCTATGCGGCCAGTGCCAAGCATGACTTATTGGGAGTCTCG
CAGGCCACGATTGATCAAGATGGTGTGGTTAGTGCGGCCACAGCTAAGGAAATGGCATCACGTTCTCGAGAACGGCTGGA
TACTGATTTTTCGTTGAGCTTCACAGGAGTTGCTGGCCCGGACGCCTTGGAAGGCCAACCGGCTGGAACAGTCTGGTTAG
GTTTAGCGCAACGGGGACAACAACCACAGGCAAAACTGTTACATTTGACGGGTACGCGATCGGCAATTCGGGAACGGAGT
GTCTTGACCGGGTTGGACTGGTTGCGACGAACATTGCAAAAAGTAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)

Competence-damaged protein (CinA)

(259-412)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB M5AZ98

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.566

99.76

0.514
  cinA Streptococcus mitis NCTC 12261

49.644

100

0.502
  cinA Streptococcus mitis SK321

49.762

100

0.502
  cinA Streptococcus pneumoniae TIGR4

48.694

100

0.493
  cinA Streptococcus pneumoniae Rx1

48.694

100

0.493
  cinA Streptococcus pneumoniae R6

48.694

100

0.493
  cinA Streptococcus pneumoniae D39

48.456

100

0.49
  cinA Bacillus subtilis subsp. subtilis str. 168

47.7

99.279

0.474
  cinA Streptococcus suis isolate S10

44.471

100

0.445