Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGD   Type   Machinery gene
Locus tag   PUW62_RS01005 Genome accession   NZ_CP118046
Coordinates   190472..190870 (+) Length   132 a.a.
NCBI ID   WP_022525973.1    Uniprot ID   -
Organism   Streptococcus anginosus strain VSI52     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 185472..195870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW62_RS00975 (PUW62_00975) - 185897..186256 (+) 360 WP_003070793.1 MerR family transcriptional regulator -
  PUW62_RS00980 (PUW62_00980) glnA 186294..187640 (+) 1347 WP_024053132.1 type I glutamate--ammonia ligase -
  PUW62_RS00985 (PUW62_00985) - 187828..188193 (+) 366 WP_024053131.1 DUF1033 family protein -
  PUW62_RS00990 (PUW62_00990) comGA 188263..189204 (+) 942 WP_024053130.1 competence type IV pilus ATPase ComGA Machinery gene
  PUW62_RS00995 (PUW62_00995) comGB 189146..190168 (+) 1023 WP_024053129.1 competence type IV pilus assembly protein ComGB Machinery gene
  PUW62_RS01000 (PUW62_01000) comGC 190165..190482 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  PUW62_RS01005 (PUW62_01005) comGD 190472..190870 (+) 399 WP_022525973.1 competence type IV pilus minor pilin ComGD Machinery gene
  PUW62_RS01010 (PUW62_01010) comGE/cglE 190842..191135 (+) 294 WP_024053127.1 competence type IV pilus minor pilin ComGE Machinery gene
  PUW62_RS01015 (PUW62_01015) comGF/cglF 191119..191556 (+) 438 WP_024053126.1 competence type IV pilus minor pilin ComGF Machinery gene
  PUW62_RS01020 (PUW62_01020) comGG/cglG 191537..191863 (+) 327 WP_022525970.1 competence type IV pilus minor pilin ComGG Machinery gene
  PUW62_RS01025 (PUW62_01025) comGH 191935..192888 (+) 954 WP_024053125.1 class I SAM-dependent methyltransferase Machinery gene
  PUW62_RS01030 (PUW62_01030) - 192935..194134 (+) 1200 WP_024053124.1 acetate kinase -

Sequence


Protein


Download         Length: 132 a.a.        Molecular weight: 15109.25 Da        Isoelectric Point: 9.7570

>NTDB_id=720632 PUW62_RS01005 WP_022525973.1 190472..190870(+) (comGD) [Streptococcus anginosus strain VSI52]
MQIKGFTLLESLLTLFITSFLLLAVSGSVRSSFEQVEEQIFFLEFEHFYRESQKLSSSAQSQLDMNFSRERISNGYNHLV
VPRSIQAPEDLTLHFDKAGGNSSLGKIVFQTKKQTITYQLYLGNGKFKKTTR

Nucleotide


Download         Length: 399 bp        

>NTDB_id=720632 PUW62_RS01005 WP_022525973.1 190472..190870(+) (comGD) [Streptococcus anginosus strain VSI52]
TTGCAGATTAAGGGATTTACGCTTTTGGAAAGTTTGCTGACATTATTTATAACGAGTTTCTTATTGCTTGCGGTGTCGGG
CTCTGTTCGTTCTTCTTTTGAACAGGTGGAAGAGCAGATTTTCTTTCTGGAGTTTGAGCATTTTTATCGGGAAAGTCAGA
AGTTGAGTAGCTCAGCTCAAAGTCAGCTGGACATGAATTTTTCTCGTGAGAGGATTTCAAATGGTTACAACCATTTGGTA
GTTCCTCGCTCGATTCAAGCGCCAGAAGATTTGACGCTTCATTTTGATAAGGCTGGTGGCAATTCATCGCTCGGAAAGAT
TGTCTTTCAGACGAAAAAGCAGACAATTACGTATCAATTATATCTAGGAAATGGGAAATTTAAGAAAACAACACGTTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus gordonii str. Challis substr. CH1

63.359

99.242

0.629

  comGD/cglD Streptococcus mitis NCTC 12261

57.364

97.727

0.561

  comGD/cglD Streptococcus mitis SK321

57.48

96.212

0.553

  comGD/cglD Streptococcus pneumoniae Rx1

57.48

96.212

0.553

  comGD/cglD Streptococcus pneumoniae D39

57.48

96.212

0.553

  comGD/cglD Streptococcus pneumoniae R6

57.48

96.212

0.553

  comGD/cglD Streptococcus pneumoniae TIGR4

56.693

96.212

0.545

  comGD Streptococcus mutans UA140

53.077

98.485

0.523

  comGD Streptococcus mutans UA159

53.077

98.485

0.523