Detailed information NTG0720437

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: NW959_RS12840
• Genome accession: NZ_CP102957
• Coordinates: 2616588..2617475 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 18-H-62
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2611588..2622475

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW959_RS12810 (NW959_12810)	-	2611616..2611699 (+)	84	WP_031797553.1	hypothetical protein	-
NW959_RS12815 (NW959_12815)	-	2611807..2612304 (-)	498	WP_001065267.1	glutathione peroxidase	-
NW959_RS12820 (NW959_12820)	-	2612314..2612574 (-)	261	WP_001791974.1	hypothetical protein	-
NW959_RS12825 (NW959_12825)	-	2612956..2613069 (-)	114	WP_072384844.1	hypothetical protein	-
NW959_RS12830 (NW959_12830)	-	2613728..2615728 (-)	2001	WP_258411888.1	ABC transporter permease	-
NW959_RS12835 (NW959_12835)	-	2615725..2616480 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
NW959_RS12840 (NW959_12840)	braS	2616588..2617475 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
NW959_RS12845 (NW959_12845)	braR	2617486..2618151 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
NW959_RS12850 (NW959_12850)	-	2618177..2618377 (-)	201	WP_000604727.1	hypothetical protein	-
NW959_RS12855 (NW959_12855)	-	2618575..2619999 (+)	1425	WP_000953743.1	alkaline phosphatase	-
NW959_RS13300	-	2620059..2620160 (-)	102	WP_000731976.1	SE2200 family small protein	-
NW959_RS12865 (NW959_12865)	-	2620282..2620737 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
NW959_RS12870 (NW959_12870)	-	2620982..2621743 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=720437 NW959_RS12840 WP_000143419.1 2616588..2617475(-) (braS) [Staphylococcus aureus strain 18-H-62]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=720437 NW959_RS12840 WP_000143419.1 2616588..2617475(-) (braS) [Staphylococcus aureus strain 18-H-62]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997