Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL263_RS09530 Genome accession   NZ_AP018938
Coordinates   1775389..1776645 (-) Length   418 a.a.
NCBI ID   WP_000642707.1    Uniprot ID   A0A0B7L5W3
Organism   Streptococcus pneumoniae strain ATCC 49619     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1770389..1781645
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL263_RS09500 (SPAT_1802) - 1770435..1770641 (-) 207 WP_000366091.1 hypothetical protein -
  EL263_RS09505 - 1770628..1770801 (-) 174 WP_000289349.1 helix-turn-helix domain-containing protein -
  EL263_RS09510 (SPAT_1803) lytA 1771160..1772116 (-) 957 WP_000405235.1 N-acetylmuramoyl-L-alanine amidase LytA -
  EL263_RS09515 (SPAT_1804) - 1772492..1773862 (-) 1371 WP_050221171.1 MATE family efflux transporter -
  EL263_RS09525 (SPAT_1805) recA 1774168..1775334 (-) 1167 WP_054387479.1 recombinase RecA Machinery gene
  EL263_RS09530 (SPAT_1806) cinA 1775389..1776645 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  EL263_RS09535 (SPAT_1807) brpA 1776729..1777745 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  EL263_RS09540 (SPAT_1808) - 1777753..1778271 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  EL263_RS09545 (SPAT_1809) tsaE 1778261..1778704 (-) 444 WP_000288230.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EL263_RS09550 (SPAT_1810) comM 1778790..1779410 (-) 621 WP_050203505.1 hypothetical protein Regulator
  EL263_RS09560 (SPAT_1811) - 1779793..1780656 (-) 864 WP_001844931.1 helix-turn-helix domain-containing protein -
  EL263_RS09565 (SPAT_1812) - 1780845..1781015 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45061.46 Da        Isoelectric Point: 4.6027

>NTDB_id=71965 EL263_RS09530 WP_000642707.1 1775389..1776645(-) (cinA) [Streptococcus pneumoniae strain ATCC 49619]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=71965 EL263_RS09530 WP_000642707.1 1775389..1776645(-) (cinA) [Streptococcus pneumoniae strain ATCC 49619]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7L5W3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.761

100

0.998
  cinA Streptococcus pneumoniae Rx1

99.522

100

0.995
  cinA Streptococcus pneumoniae R6

99.522

100

0.995
  cinA Streptococcus pneumoniae D39

99.282

100

0.993
  cinA Streptococcus mitis SK321

93.78

100

0.938
  cinA Streptococcus mitis NCTC 12261

93.541

100

0.935
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455

Multiple sequence alignment