Detailed information NTG0071937

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: EL263_RS04725
• Genome accession: NZ_AP018938
• Coordinates: 882981..883631 (+)
• Length: 216 a.a.
• NCBI ID: WP_114880828.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain ATCC 49619
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 877981..888631

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL263_RS04680 (SPAT_0878)	-	878465..878680 (+)	216	WP_001232082.1	YozE family protein	-
EL263_RS04685 (SPAT_0879)	-	878766..879734 (+)	969	WP_000658183.1	PhoH family protein	-
EL263_RS04695 (SPAT_0880)	-	879927..880427 (+)	501	WP_000566982.1	GNAT family N-acetyltransferase	-
EL263_RS04700	-	880430..880755 (+)	326	Protein_888	TfoX/Sxy family protein	-
EL263_RS11780	ald	881056..882167 (-)	1112	Protein_889	alanine dehydrogenase	-
EL263_RS04720 (SPAT_0884)	-	882344..882913 (+)	570	WP_114880827.1	GNAT family N-acetyltransferase	-
EL263_RS04725 (SPAT_0885)	comEA/celA/cilE	882981..883631 (+)	651	WP_114880828.1	helix-hairpin-helix domain-containing protein	Machinery gene
EL263_RS04730 (SPAT_0886)	comEC/celB	883615..885855 (+)	2241	WP_044727637.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL263_RS04735	-	886034..886222 (+)	189	WP_001809102.1	hypothetical protein	-
EL263_RS04740 (SPAT_0887)	-	886254..886841 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
EL263_RS04745 (SPAT_0889)	-	886845..888025 (+)	1181	Protein_895	hypothetical protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23274.65 Da
• Isoelectric Point: 6.0746

>NTDB_id=71937 EL263_RS04725 WP_114880828.1 882981..883631(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain ATCC 49619]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNVQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
SLEELKQVKRLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=71937 EL263_RS04725 WP_114880828.1 882981..883631(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain ATCC 49619]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATGTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGAGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae D39	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae R6	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis NCTC 12261	94.907	100	0.949
comEA/celA/cilE	Streptococcus mitis SK321	90.278	100	0.903
comEA	Lactococcus lactis subsp. cremoris KW2	43.172	100	0.454
comEA	Streptococcus thermophilus LMD-9	39.738	100	0.421
comEA	Bacillus subtilis subsp. subtilis str. 168	41.053	87.963	0.361