Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   EL277_RS12645 Genome accession   NZ_AP018936
Coordinates   514796..515707 (-) Length   303 a.a.
NCBI ID   WP_001827226.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NU83127     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 509796..520707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL277_RS02665 (SPNU_0500) - 510139..510468 (-) 330 WP_000132572.1 hypothetical protein -
  EL277_RS02670 (SPNU_0501) - 510745..511083 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  EL277_RS02675 (SPNU_0502) comE/blpR 511088..511825 (+) 738 WP_001219119.1 response regulator transcription factor Regulator
  EL277_RS02680 (SPNU_0504) - 511839..513168 (+) 1330 Protein_503 sensor histidine kinase -
  EL277_RS02685 (SPNU_0505) blpC 513212..513367 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  EL277_RS02690 (SPNU_0506) - 513424..514785 (-) 1362 WP_001069103.1 bacteriocin secretion accessory protein -
  EL277_RS12645 (SPNU_0507) comA/nlmT 514796..515707 (-) 912 WP_001827226.1 ATP-binding cassette domain-containing protein Regulator
  EL277_RS12650 (SPNU_0508) comA/nlmT 515697..516422 (-) 726 WP_167750760.1 ABC transporter transmembrane domain-containing protein Regulator
  EL277_RS12655 (SPNU_0509) comA/nlmT 516367..516954 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  EL277_RS02705 (SPNU_0510) - 517236..517439 (+) 204 WP_001093262.1 bacteriocin class II family protein -
  EL277_RS02710 (SPNU_0511) - 517757..517960 (+) 204 WP_000411016.1 hypothetical protein -
  EL277_RS02720 - 518963..519767 (+) 805 Protein_511 IS5 family transposase -
  EL277_RS02725 (SPNU_0515) blpM 519917..520171 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  EL277_RS02730 (SPNU_0516) blpN 520187..520390 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 34051.15 Da        Isoelectric Point: 7.2767

>NTDB_id=71843 EL277_RS12645 WP_001827226.1 514796..515707(-) (comA/nlmT) [Streptococcus pneumoniae strain NU83127]
MSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYG
FGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIFNGSI
LENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSGLDVL
TEKKVIDNLMSLTNKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 912 bp        

>NTDB_id=71843 EL277_RS12645 WP_001827226.1 514796..515707(-) (comA/nlmT) [Streptococcus pneumoniae strain NU83127]
ATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATAT
TATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAAT
TTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGT
TTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTC
TGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATA
TTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATT
TTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCG
TCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAAC
GAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTG
ACTGAGAAAAAGGTTATAGATAATCTTATGTCCCTAACTAATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGC
CGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAAGCGC
AAGGATTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(86-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.854

99.67

0.716
  comA Streptococcus mitis NCTC 12261

66.007

100

0.66
  comA Streptococcus gordonii str. Challis substr. CH1

65.461

100

0.657
  comA Streptococcus pneumoniae D39

65.347

100

0.653
  comA Streptococcus pneumoniae R6

65.347

100

0.653
  comA Streptococcus pneumoniae Rx1

65.347

100

0.653
  comA Streptococcus mitis SK321

65.017

100

0.65
  comA Streptococcus pneumoniae TIGR4

65.017

100

0.65

Multiple sequence alignment