Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   NQZ84_RS00395 Genome accession   NZ_CP102094
Coordinates   68776..69957 (+) Length   393 a.a.
NCBI ID   WP_044683390.1    Uniprot ID   A0AAN2RIA6
Organism   Streptococcus suis strain 12RC1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 63776..74957
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ84_RS00370 (NQZ84_00370) mutL 64130..66067 (+) 1938 WP_172058503.1 DNA mismatch repair endonuclease MutL -
  NQZ84_RS00375 (NQZ84_00375) ruvA 66106..66696 (+) 591 WP_011921679.1 Holliday junction branch migration protein RuvA -
  NQZ84_RS00380 (NQZ84_00380) - 66949..67509 (+) 561 WP_044683393.1 DNA-3-methyladenine glycosylase I -
  NQZ84_RS00385 (NQZ84_00385) - 67583..67993 (+) 411 WP_044683392.1 helix-turn-helix transcriptional regulator -
  NQZ84_RS00390 (NQZ84_00390) - 67966..68631 (+) 666 WP_044683391.1 CPBP family intramembrane glutamic endopeptidase -
  NQZ84_RS00395 (NQZ84_00395) cinA 68776..69957 (+) 1182 WP_044683390.1 competence/damage-inducible protein A Machinery gene
  NQZ84_RS00400 (NQZ84_00400) recA 70009..71160 (+) 1152 WP_044668625.1 recombinase RecA Machinery gene
  NQZ84_RS00405 (NQZ84_00405) spx 71396..71794 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  NQZ84_RS00410 (NQZ84_00410) - 71894..72160 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  NQZ84_RS00415 (NQZ84_00415) ruvX 72160..72579 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  NQZ84_RS00420 (NQZ84_00420) - 72591..72911 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  NQZ84_RS00425 (NQZ84_00425) - 73069..73191 (+) 123 WP_257048998.1 hypothetical protein -
  NQZ84_RS00430 (NQZ84_00430) rpsJ 73400..73708 (+) 309 WP_002939332.1 30S ribosomal protein S10 -
  NQZ84_RS00435 (NQZ84_00435) rplC 73921..74547 (+) 627 WP_011921686.1 50S ribosomal protein L3 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42918.76 Da        Isoelectric Point: 4.3708

>NTDB_id=714276 NQZ84_RS00395 WP_044683390.1 68776..69957(+) (cinA) [Streptococcus suis strain 12RC1]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVASQRSDLVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=714276 NQZ84_RS00395 WP_044683390.1 68776..69957(+) (cinA) [Streptococcus suis strain 12RC1]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCAGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
CTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGTCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGTTTTTTTGGCATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

96.947

100

0.969
  cinA Streptococcus pneumoniae R6

56.25

100

0.595
  cinA Streptococcus mitis SK321

56.25

100

0.595
  cinA Streptococcus pneumoniae TIGR4

56.25

100

0.595
  cinA Streptococcus pneumoniae Rx1

56.25

100

0.595
  cinA Streptococcus mutans UA159

56.934

100

0.595
  cinA Streptococcus mitis NCTC 12261

56.01

100

0.593
  cinA Streptococcus pneumoniae D39

56.01

100

0.593
  cinA Bacillus subtilis subsp. subtilis str. 168

41.176

99.491

0.41