Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   NP948_RS13405 Genome accession   NZ_CP102070
Coordinates   2726641..2727885 (-) Length   414 a.a.
NCBI ID   WP_010710870.1    Uniprot ID   -
Organism   Enterococcus faecalis strain JF3A-4253     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2721641..2732885
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NP948_RS13380 - 2721955..2723418 (-) 1464 WP_002407853.1 glycoside hydrolase family 1 protein -
  NP948_RS13385 - 2723400..2723741 (-) 342 WP_104806899.1 PTS lactose/cellobiose transporter subunit IIA -
  NP948_RS13390 - 2723761..2725011 (-) 1251 WP_016627527.1 PTS sugar transporter subunit IIC -
  NP948_RS13395 - 2725016..2725321 (-) 306 WP_010821936.1 hypothetical protein -
  NP948_RS13400 recA 2725481..2726527 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  NP948_RS13405 cinA 2726641..2727885 (-) 1245 WP_010710870.1 competence/damage-inducible protein A Machinery gene
  NP948_RS13410 - 2728077..2729282 (+) 1206 WP_016627528.1 hypothetical protein -
  NP948_RS13415 - 2729361..2729990 (-) 630 WP_016614229.1 NAD(P)-dependent oxidoreductase -
  NP948_RS13420 - 2730049..2730474 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  NP948_RS13425 - 2730563..2730946 (-) 384 WP_002354850.1 YccF domain-containing protein -
  NP948_RS13430 - 2731110..2731901 (+) 792 WP_002367471.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45193.29 Da        Isoelectric Point: 4.6698

>NTDB_id=714139 NP948_RS13405 WP_010710870.1 2726641..2727885(-) (cinA) [Enterococcus faecalis strain JF3A-4253]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=714139 NP948_RS13405 WP_010710870.1 2726641..2727885(-) (cinA) [Enterococcus faecalis strain JF3A-4253]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAATTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCGAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCCCAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGCGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.537

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.3

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.591

100

0.517
  cinA Streptococcus pneumoniae D39

50.355

100

0.514
  cinA Streptococcus pneumoniae R6

50.118

100

0.512
  cinA Streptococcus pneumoniae Rx1

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437