Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   NOV99_RS01990 Genome accession   NZ_CP101844
Coordinates   392164..392826 (+) Length   220 a.a.
NCBI ID   WP_002935348.1    Uniprot ID   A0AB37G4C2
Organism   Streptococcus suis strain 2018WUSS151     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 387164..397826
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NOV99_RS01970 (NOV99_01970) - 387880..388809 (-) 930 WP_002937175.1 ABC transporter substrate-binding protein -
  NOV99_RS01975 (NOV99_01975) - 388822..389607 (-) 786 WP_014636900.1 ABC transporter ATP-binding protein -
  NOV99_RS01980 (NOV99_01980) - 389759..391204 (-) 1446 WP_024390938.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  NOV99_RS01985 (NOV99_01985) - 391351..392097 (+) 747 WP_014636901.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  NOV99_RS01990 (NOV99_01990) comEA/celA/cilE 392164..392826 (+) 663 WP_002935348.1 helix-hairpin-helix domain-containing protein Machinery gene
  NOV99_RS01995 (NOV99_01995) comEC/celB 392810..395047 (+) 2238 WP_240020621.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  NOV99_RS02005 (NOV99_02005) - 395371..396027 (+) 657 WP_002935353.1 CBS domain-containing protein -
  NOV99_RS02010 (NOV99_02010) - 396121..396948 (+) 828 WP_002935354.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23297.93 Da        Isoelectric Point: 4.0751

>NTDB_id=712301 NOV99_RS01990 WP_002935348.1 392164..392826(+) (comEA/celA/cilE) [Streptococcus suis strain 2018WUSS151]
MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQTAQTSSSSDLVEETSTEASEEPSQLVVDVK
GAVVKPGLYTLEADARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSSEEKSTSQVN
LNTATEADLQTISGIGAKRATDIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=712301 NOV99_RS01990 WP_002935348.1 392164..392826(+) (comEA/celA/cilE) [Streptococcus suis strain 2018WUSS151]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCCGCAGTGGCTGGCTTGCT
AATGGCGACGTTCTTAATATTCAGCCAACCAGCCAAGTCTGATCAGACAGGCCTGACAGATTTTCCGCAGACCGCACAAA
CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGCAAGTGAAGAGCCCAGCCAGCTGGTTGTTGATGTCAAA
GGAGCGGTAGTAAAACCAGGACTCTACACTTTAGAAGCTGATGCGCGTGTTAATGATGCAGTTGAGGCGGCTGGTGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAAGCGGTGGTCTATGTGGCCAGCAAGG
ACGAAAACATCTCGGTGGTGGCTAGCACGACTGCTAGCTCTGCTATGTCCTCAGAAGAAAAAAGCACAAGTCAGGTCAAT
CTGAATACGGCGACCGAGGCTGACTTGCAGACCATTTCTGGTATTGGTGCCAAGCGAGCGACGGACATTATCGCCTATCG
TGAGGCCAACGGTGGCTTCAAGTCGGTGGATGACCTCAACAATGTGTCGGGCATCGGCGACAAGACTATGGAAAGCATCC
GGCCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-130)

Helix-hairpin-helix motif (HHH_3)

(156-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.848

98.636

0.482
  comEA/celA/cilE Streptococcus pneumoniae Rx1

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus pneumoniae D39

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus pneumoniae R6

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus mitis NCTC 12261

47.248

99.091

0.468
  comEA/celA/cilE Streptococcus mitis SK321

46.154

100

0.464
  comEA Streptococcus thermophilus LMD-9

59.494

71.818

0.427
  comEA Lactococcus lactis subsp. cremoris KW2

37.168

100

0.382
  comEA Bacillus subtilis subsp. subtilis str. 168

37.915

95.909

0.364