Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NN994_RS01480 Genome accession   NZ_CP101646
Coordinates   265078..265977 (+) Length   299 a.a.
NCBI ID   WP_064355637.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain UCCSt95     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 260078..270977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NN994_RS01460 (NN994_01460) trkA 261214..262563 (-) 1350 WP_064355641.1 Trk system potassium transporter TrkA -
  NN994_RS01465 (NN994_01465) - 262852..263361 (+) 510 WP_064355639.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  NN994_RS01470 (NN994_01470) - 263673..264230 (+) 558 WP_002949523.1 ECF transporter S component -
  NN994_RS01475 (NN994_01475) - 264233..264883 (+) 651 WP_011226853.1 phosphatase PAP2 family protein -
  NN994_RS01480 (NN994_01480) comR 265078..265977 (+) 900 WP_064355637.1 helix-turn-helix domain-containing protein Regulator
  NN994_RS01485 (NN994_01485) - 266215..266796 (+) 582 Protein_237 cysteine peptidase family C39 domain-containing protein -
  NN994_RS01490 (NN994_01490) comA 266781..267071 (+) 291 WP_194238295.1 ABC transporter transmembrane domain-containing protein Regulator
  NN994_RS01495 (NN994_01495) comA 267414..267623 (+) 210 WP_002946147.1 hypothetical protein Regulator
  NN994_RS01500 (NN994_01500) - 267678..268246 (+) 569 Protein_240 ATP-binding cassette domain-containing protein -
  NN994_RS01505 (NN994_01505) - 268354..268671 (+) 318 WP_011225454.1 DUF805 domain-containing protein -
  NN994_RS01510 (NN994_01510) - 268634..268918 (-) 285 WP_014727318.1 hypothetical protein -
  NN994_RS01515 (NN994_01515) - 269158..270054 (-) 897 WP_224102957.1 urease cluster protein -
  NN994_RS01520 (NN994_01520) - 270459..270974 (+) 516 WP_002949547.1 AmiS/UreI family transporter -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35323.71 Da        Isoelectric Point: 5.0061

>NTDB_id=711197 NN994_RS01480 WP_064355637.1 265078..265977(+) (comR) [Streptococcus thermophilus strain UCCSt95]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDFMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=711197 NN994_RS01480 WP_064355637.1 265078..265977(+) (comR) [Streptococcus thermophilus strain UCCSt95]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTTATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(75-292)

Helix-turn-helix (HTH_3)

(11-66)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus thermophilus LMG 18311

99.331

100

0.993
  comR Streptococcus thermophilus LMD-9

98.662

100

0.987
  comR Streptococcus salivarius strain HSISS4

94.649

100

0.946
  comR Streptococcus salivarius SK126

93.98

100

0.94
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

41.806

100

0.418