Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   NLY76_RS00375 Genome accession   NZ_CP100430
Coordinates   64825..66006 (+) Length   393 a.a.
NCBI ID   WP_044684331.1    Uniprot ID   A0AB33UHH6
Organism   Streptococcus suis strain LSS42     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 59825..71006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY76_RS00360 (NLY76_00360) mutL 61218..63155 (+) 1938 WP_044684329.1 DNA mismatch repair endonuclease MutL -
  NLY76_RS00365 (NLY76_00365) ruvA 63194..63784 (+) 591 WP_044684330.1 Holliday junction branch migration protein RuvA -
  NLY76_RS00370 (NLY76_00370) - 64219..64788 (+) 570 WP_012774893.1 DNA-3-methyladenine glycosylase I -
  NLY76_RS00375 (NLY76_00375) cinA 64825..66006 (+) 1182 WP_044684331.1 competence/damage-inducible protein A Machinery gene
  NLY76_RS00380 (NLY76_00380) recA 66058..67209 (+) 1152 WP_024416946.1 recombinase RecA Machinery gene
  NLY76_RS00385 (NLY76_00385) spx 67445..67843 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  NLY76_RS00390 (NLY76_00390) - 67943..68209 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  NLY76_RS00395 (NLY76_00395) ruvX 68209..68628 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  NLY76_RS00400 (NLY76_00400) - 68640..68960 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  NLY76_RS00405 (NLY76_00405) - 69217..69795 (+) 579 WP_044669569.1 nucleotidyltransferase family protein -
  NLY76_RS00410 (NLY76_00410) rpsJ 70455..70763 (+) 309 WP_014735259.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 43031.92 Da        Isoelectric Point: 4.3708

>NTDB_id=705183 NLY76_RS00375 WP_044684331.1 64825..66006(+) (cinA) [Streptococcus suis strain LSS42]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVARQRSDLVFLCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVVGQLGIESGWLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=705183 NLY76_RS00375 WP_044684331.1 64825..66006(+) (cinA) [Streptococcus suis strain LSS42]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCCGTACTGG
AAGTAGCCCGTCAGCGGAGCGACTTGGTCTTTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
CTGGCAACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGACC
AGGTCGTGTTCGCACACCTAATAATGAGCGTCAAGCACAGATTGTAGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTAGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGCATTGG
TGAAAGCCAGTTAGTGACTGTTTTGGCGGACTTAATCGACAAGCAGACAGATCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCGTCGGTCAGCTAGGGATAGAATCGGGCTGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATACCTCACTTTGGCTACGCCCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-392)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

97.455

100

0.975
  cinA Streptococcus mutans UA159

56.448

100

0.59
  cinA Streptococcus pneumoniae R6

55.529

100

0.588
  cinA Streptococcus mitis SK321

55.529

100

0.588
  cinA Streptococcus pneumoniae TIGR4

55.529

100

0.588
  cinA Streptococcus pneumoniae Rx1

55.529

100

0.588
  cinA Streptococcus mitis NCTC 12261

55.288

100

0.585
  cinA Streptococcus pneumoniae D39

55.288

100

0.585
  cinA Bacillus subtilis subsp. subtilis str. 168

41.91

95.929

0.402