Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NIN90_RS12875 Genome accession   NZ_CP100422
Coordinates   2786510..2787736 (+) Length   408 a.a.
NCBI ID   WP_055466515.1    Uniprot ID   A0A0Q2QY84
Organism   Vibrio furnissii strain 104486766     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2781510..2792736
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NIN90_RS12850 fldB 2781893..2782414 (+) 522 WP_055466520.1 flavodoxin FldB -
  NIN90_RS12855 ampD 2782450..2783004 (-) 555 WP_232658178.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  NIN90_RS12860 nadC 2783153..2784040 (+) 888 WP_055466518.1 carboxylating nicotinate-nucleotide diphosphorylase -
  NIN90_RS12865 - 2784287..2784736 (+) 450 WP_055466517.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  NIN90_RS12870 pilB 2784743..2786431 (+) 1689 WP_232658179.1 type IV-A pilus assembly ATPase PilB Machinery gene
  NIN90_RS12875 pilC 2786510..2787736 (+) 1227 WP_055466515.1 type II secretion system F family protein Machinery gene
  NIN90_RS12880 pilD 2787788..2788657 (+) 870 WP_004729087.1 A24 family peptidase Machinery gene
  NIN90_RS12885 coaE 2788660..2789268 (+) 609 WP_014204457.1 dephospho-CoA kinase -
  NIN90_RS12890 zapD 2789301..2790041 (+) 741 WP_004729090.1 cell division protein ZapD -
  NIN90_RS12895 yacG 2790099..2790296 (+) 198 WP_004729092.1 DNA gyrase inhibitor YacG -
  NIN90_RS12900 parC 2790389..2792662 (-) 2274 WP_232658180.1 DNA topoisomerase IV subunit A -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44841.13 Da        Isoelectric Point: 10.5674

>NTDB_id=705080 NIN90_RS12875 WP_055466515.1 2786510..2787736(+) (pilC) [Vibrio furnissii strain 104486766]
MKPNKAAELKNFRWKGINSSGRKVAGHTLAISEIEVRDKLKEQHIQVKKIKKGSISLLTRLTHRVKTRDITLLTRQLSTM
LTTGVPIVQALKLVGDNHRKAEMKSILAQVTKGVEAGTPMSKAMRTASPHFDALYVDLIATGEQSGNLAEVFERLATYRE
KSEQLRAKVIKALIYPAMVMLVALGVSYLMLTMVIPEFESMFKGFGAELPWFTQQILKLSHGVQAYSLWGLLATSAGLLA
LKTARNKSLVFRLKTSRLSLRFPVIGAVLAKAAIAKFSRTLATSFSAGIPILASLKTTAKTAGNVHFETAIQEVHRHTAA
GMPMYIAMRNTDAFPEMVLQMVMIGEESGKLDDMLNKVATIYEFEVDNTVDNLGKILEPLIIVFLGVVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=705080 NIN90_RS12875 WP_055466515.1 2786510..2787736(+) (pilC) [Vibrio furnissii strain 104486766]
ATGAAACCAAATAAAGCTGCCGAATTGAAAAACTTCCGCTGGAAAGGCATCAACAGCTCCGGACGAAAAGTTGCCGGACA
CACCTTGGCCATCAGTGAAATCGAAGTGCGAGACAAGCTCAAAGAGCAGCACATTCAGGTGAAGAAGATCAAAAAAGGCA
GCATTTCACTGCTGACTCGCCTCACCCACCGTGTCAAGACTCGCGACATCACCCTGCTTACACGCCAGCTTTCCACTATG
CTGACTACAGGTGTGCCCATCGTTCAAGCGTTGAAACTGGTTGGCGACAATCACCGCAAAGCAGAAATGAAATCGATTCT
GGCCCAAGTCACCAAAGGGGTAGAAGCTGGCACCCCAATGTCCAAAGCGATGCGCACCGCCAGCCCACATTTTGATGCGC
TGTACGTTGACCTCATAGCCACCGGCGAGCAATCCGGGAATTTGGCCGAAGTGTTTGAGCGCCTTGCCACCTATCGAGAA
AAAAGCGAACAACTGCGCGCCAAAGTGATCAAGGCGCTGATCTATCCGGCAATGGTGATGTTGGTCGCGTTGGGCGTCTC
TTATCTGATGCTGACCATGGTCATTCCCGAGTTTGAAAGCATGTTCAAAGGCTTTGGCGCAGAGCTCCCTTGGTTTACCC
AGCAAATTCTAAAACTCTCCCACGGCGTGCAAGCCTATAGCCTATGGGGTTTACTGGCGACCAGCGCTGGCCTATTGGCG
CTCAAAACCGCGCGCAACAAATCATTGGTCTTTCGATTGAAAACCAGCCGCCTTAGCTTGCGATTTCCTGTTATCGGCGC
GGTCTTGGCCAAGGCTGCCATTGCCAAATTCAGCCGTACATTGGCCACAAGTTTTAGCGCCGGTATACCGATTCTGGCCA
GTTTAAAAACCACCGCCAAAACCGCCGGCAACGTCCATTTTGAAACCGCGATTCAAGAGGTACATCGCCATACCGCGGCA
GGCATGCCGATGTACATCGCCATGCGCAATACCGACGCATTTCCGGAGATGGTGCTGCAAATGGTGATGATTGGCGAAGA
GTCGGGCAAGCTTGACGACATGCTGAACAAAGTCGCGACTATTTATGAGTTTGAAGTCGACAATACCGTGGACAATCTGG
GTAAAATTCTCGAGCCGCTGATCATCGTCTTTCTGGGAGTGGTCGTTGGCGGGCTGGTGGTTGCGATGTACCTCCCCATC
TTTAACTTAATGAGTGTATTGGGTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Q2QY84

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

84.559

100

0.846
  pilC Vibrio campbellii strain DS40M4

73.945

98.775

0.73
  pilC Acinetobacter baumannii D1279779

41.422

100

0.414
  pilC Pseudomonas stutzeri DSM 10701

41.832

99.02

0.414
  pilC Legionella pneumophila strain ERS1305867

42.105

97.794

0.412
  pilC Acinetobacter baylyi ADP1

40.196

100

0.402
  pilG Neisseria gonorrhoeae MS11

39.163

99.51

0.39
  pilG Neisseria meningitidis 44/76-A

38.916

99.51

0.387